Báo cáo y học: "Determinants of the daily rhythm of blood fluidity" doc

... analy- sis was performed early because of safety concerns and revealed increased hospital mortality in patients treated by DIS. Because the study primary endpoint might affect mortal- ity, the ... mem- bers of the DSMB and were not involved in the DSMB's data analysis. The study was not terminated because of the finding of increased hospital mortality in patients trea...

Ngày tải lên: 25/10/2012, 10:35

... evaluated, the period of study (only at birth or in early neonatal period or prenatal or the whole infant period are included), the completeness of ascertainment, the diagnostic skill of experts, ... characteristics of the study population, etc. In Hungary the total prevalence of congenital abnormalities was 66.83 per 1000 informative offspring in the 1980s and...

Ngày tải lên: 02/11/2012, 11:12

... several examples of theory being misled by mistaken data. Indeed, early reports of SMGT were compared with the (then contemporary) claims of “cold fusion” in physics [36]. By contrast, the second ... germline gene therapy. 2. Criteria for Assessing Applicability to Human Germline Gene Therapy An ideal gene transfer system in the context of human germline gene therapy would h...

Ngày tải lên: 03/11/2012, 10:01

... indicating that the environ- ment of tryptophan residues is essentially conserved in the mutant enzyme. On the other hand, the absence of major differences in the CD spectra of the wild-type and D153N agmatinases ... we conclude that the lower activity of the mutant may be ascribed to the loss of an acceptor hydrogen bond to a metal-bound hydroxide, as a consequenc...

Ngày tải lên: 21/02/2014, 01:21

... Stereochemistry of the isoprenylation of tryptophan catalyzed by 4-(g,g-dimethylallyl) tryptophan synthase from Claviceps, the first pathway-specific enzyme in ergot alkaloid biosynthesis. J. Am. ... H A -hydrogen of IPP. In both cases, scrambling of the label takes place within the IPP pool and the error is then transcribed into the DMAPP pool by the normal action of t...

Ngày tải lên: 22/02/2014, 07:20

... particle density of the polydisperse sol- utes. For the functional dependence between the density and molar mass of the fractionated emulsion particles, we assumed a spherical monolayer of Myr 2 Gro-PCho surrounding ... diffusion coefficient measured by dynamic light scattering. Because of the size of the emulsion particles, diffusional broadening of the flotation profi...

Ngày tải lên: 08/03/2014, 09:20

... that further medical therapy will still be required to manage their disease but that marsupialization of the eth- moid sinus cavity with surgical widening of the ostia of the secondary sinuses ... tissue contraction. Obviously, another indication for revision surgery is recurrent polyp disease that can- not be managed medically or in the office. Technical State of the Art T...

Ngày tải lên: 08/08/2014, 20:23

... x-rays have a sensitivity of only about 25% for cartilage loss seen on MRI. The x-ray underestimates cartilage loss occurring in the posterior sweep of the femur and often in the upslope of the ... currently ongoing. The effects of patellar braces on patellar malalignment are also unclear, but braces may push the patella into the trochlear groove [67], thereby increasi...

Ngày tải lên: 09/08/2014, 01:22

... consequence of the activation of many cell populations and, ultimately, of the upregulation of proinflammatory cyto- kines [19,20]. By whichever means they themselves become activated, they induce ... 1 Composite indices are the best depicters of disease activity. The degree of disease activity at the start of a disease-modifying therapy is a major determinant of th...

Ngày tải lên: 09/08/2014, 01:22

... notably, this was not at the expense of specificity, which was 94% when CB10 was used. Discussion The most significant finding from our study was that in RA the use in an ELISA of fragments of the ... molecule, particularly CB10, as antigen markedly increased the sen- sitivity of detection of antibodies in serum against NCII from Figure 2 Purification of CB peptides of...

Ngày tải lên: 09/08/2014, 01:23