Báo cáo y học: " Efficacy and hypnotic effects of melatonin in shift-work nurses: double-blind, placebo-controlled crossover trial" ppt

... melatonin in patients with insomnia than in healthy controls, and Haimov et al [31] found lower levels of urinary 6-sulpha- toxymelatonin in elderly patients with insomnia than in healthy elderly ... about melatonin effect on different kinds of insomnia parameters (difficulty falling asleep, difficulty staying asleep, problem waking up too early, and sleep quality) causing...

Ngày tải lên: 10/08/2014, 09:20

... analyzed the possible in vivo effect of Rituximab on the apoptosis of PBMNCs in the patients included in this study. Interestingly, we found an important and significant increase in the percent of ... activated in vitro with phytohe- magglutinin (PHA). The percent of CD4+ lymphocytes synthesizing IL-10 was determined using the appropriate commercial kit (Miltenyi), fol- lo...

Ngày tải lên: 09/08/2014, 08:22

... Namboodiri AM, Singh I: Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. J Clin Invest 1997, 100:2671-2679. 46. ... al. 57 Effects of statins beyond lipid lowering in cardiovascular disease? The increasing body of evidence for the efficacy of statins in protecting against va...

Ngày tải lên: 09/08/2014, 06:22

... therapy by exploring medicinal plants: A casestudy of Uttaranchal State in India. In Indigenous Knowledge: Transforming the Academy, Proceedings of an International Conferences Pennsylvania: Pennsylvania ... impressive array of speci es and genetic diversity make India one of the 12 mega-biodi- versity countries of the world. Forest represents one of the dominant components...

Ngày tải lên: 10/08/2014, 09:22

... (dehydro- genation, hydroxylation, and N-dealkylation), mainly by cytochrome P450 2D6 (CYP2D6) and cytochrome P450 3A4 (CYP3A4) [60]. The parenteral drug is excreted only in traces. There is only ... Pharmacokinetics and tolerability of intra- muscular, oral and intravenous aripiprazole in healthy subjects and in patients with schizophrenia. Clin Pharmacokinet 2008, 47:475-4...

Ngày tải lên: 08/08/2014, 23:21

... are in agreement with previous studies that have determined the function of COMP to be that of maintaining the integrity and properties of the col- lagen II network by bridging collagen II and ... small and the same trends are expected to hold. For instance, a protein expression study using skeletally mature and immature rabbit fibrochondrocytes expanded in primary and sec...

Ngày tải lên: 09/08/2014, 10:21

... treat- ment effects were observed for the final laboratory aMT6s Determining Urinary aMT6s AcrophaseFigure 3 Determining Urinary aMT6s Acrophase. An example of analyzing urinary aMT6s is shown. The yellow ... after arising. This repre- sented the final CES-D score. Assays Urinary concentrations of 6-sulphatoxymelatonin (aMT6s), the primary metabolite of melatonin, were assayed with a...

Ngày tải lên: 10/08/2014, 09:20

... activity due to redox-sensitive cysteine residues[27,28]. Thus, the effect of AS101 in our experimental system may be mediated by in hibition of two steps in the NFB pathway by modifying specific ... enable its anti-inflammatory effects with respect to its ability to reduce pro-inflammatory cytokines and inhibit iNOS expression and NO release in LPS-stimulated RAW264.7 macr...

Ngày tải lên: 11/08/2014, 08:22

... pharmacy data. While clinical disease activity measures remain the gold standard for assessing effectiveness in RA, the many large administrative data sources in the U.S. and internationally are ... written informed consent. VARA contains demographic, clinical and RA-specific information including disease activity scores (DAS), as assessed by physicians using the DAS28 [23] and...

Ngày tải lên: 25/10/2012, 10:45

... cascade of cytokines and chemokines necessary for tissue eosinophilia without involvement of draining lymphoid tissues. We studied the induction of lung allergic in- flammation in mice lacking ... the last intranasal challenge. Briefly, mice were maintained inside a whole-body plethysmograph (Buxco, Troy, NY) capable of meas- uring changes in airflow and trans-thoracic p...

Ngày tải lên: 03/11/2012, 11:24