Báo cáo y học: "Ischemic stroke destabilizes circadian rhythms" potx

... ischemic stroke on circadian rhythm regulation, which is strongly linked to sleep and mood, may thus potentially influence long- term recovery in stroke patients. In humans, the daily expression ... consistently affected in this model of stroke. These results suggest that stroke may unmask interactions between the parietal/CPu locomotor rhythm generating system and other SCN-driven r...

Ngày tải lên: 10/08/2014, 09:20

... author Abstract Every physiological function in the human body exhibits some form of circadian rhythmicity. Under pathological conditions, however, circadian rhythmicity may be dusrupted. Patients ... showed statistically significant circadian rhythmicity (Figure 4b, Table 1). Discussion Circadian rhythmicity is a highly conserved biological function that is found in every living org...

Ngày tải lên: 10/08/2014, 09:20

... yours — you keep the copyright Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp BioMedcentral Journal of Circadian Rhythms 2006, 4:10 http://www.jcircadianrhythms.com/content/4/1/10 Page ... and powerful anal- ysis. • Data should be collected regularly during each oscilla- tory period (increasing frequency spectrum) and for many successive cycles (increasin...

Ngày tải lên: 10/08/2014, 09:20

... rhythm was delayed from 3.7 ± 1.3 h in wild-type mice to 5.5 ± 0.7 h in the Clock mutants. The acrophase of the lymphocyte rhythm was also signifi- cantly delayed from 4.9 ± 1.1 h in wild-type ... Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113–8657, Japan, 4 Department of Hygiene and Public Health, School of Human Sciences, Waseda University, 2-579-15 Mikajima, Tokoroz...

Ngày tải lên: 10/08/2014, 09:20

... of dendritic cell physiology may be selectively influenced by the circadian system. This implies caution in the moni- toring of these immunoregulatory effects which may sub- stantially fluctuate during ... murine circadian rhythmicity. This is the first study implicating galectin-1 in the mammalian circadian system. Background Circadian systems represent an endogenous mechanism adapt...

Ngày tải lên: 10/08/2014, 09:20

... Surgery, Sutcuimam University, School of Medicine, Kahramanmaras¸, Turkey, 2 Dept. Of Pathology, Sutcuimam University, School of Medicine, Kahramanmaras¸, Turkey and 3 Dept. Of Biochemistry, ... the severity of the I/R injury by inhibiting neutrophil adhesion in postcapillary venules and by decreasing microvascular constriction [20]. In our study, axonal changes at 7 th day were evaluated....

Ngày tải lên: 10/08/2014, 09:22

... nerve palsy usually manifests as Bell’spalsy, which is commonly described as an acute peripheral facial palsy of unknown cause [1]. Bell’s palsy typically presents with a sudden onset (usually over ... bilaterally. MRI of the head was initially read as negative for acute stroke. Bell’s palsy appeared less likely because of the acuity of his presentation, encephalopathy-like imaging, and hype...

Ngày tải lên: 10/08/2014, 23:21

... activity, depending on the sensibility of the receptors and the availability of dopamine (DA). The D 2 receptors are present both presy- naptically (as autoinhibitory targets) and postsynaptically (as ... delusional disorder [6]. Psychiatric disorders sharing the 'psychotic' feature have been traditionally effectively treated using typical antipsy- chotics (AT). More recently clini...

Ngày tải lên: 08/08/2014, 23:21

... Isotretinoin therapy and depression: evidence for an association. Ir J Psych Med 1998, 15:58-60. 24. Barak Y, Wohl W, Greenberg Y, Bar Dayan Y, Friedman T, Shoval G, Knobler HY: Affective psychosis following ... the dentate gyrus in schiz- ophrenia. Psychiatry Res 2005, 133:13-21. 60. Dunlop BW, Nemeroff CB: The role of dopamine in the patho- physiology of depression. Arch Gen Psychiatry 2...

Ngày tải lên: 08/08/2014, 23:21

... Design and synthesis of a series of (2R)-N(4)- hydroxy-2-(3-hydroxybenzyl)-N(1)-[(1S,2R)-2-hydroxy-2,3- dihydro-1H-inden-1-yl]butanediamide derivatives as potent, selective, and orally bioavailable ... Liao Y, Ishikura F, Yoshinaka T, Ohmoto H, Node K, Yoshino K, Ishiguro H, Asanuma H, Sanada S, Matsumura Y, Takeda H, Beppu S, Tada M, Hori M, Higashiyama S: Cardiac hypertrophy is inhibited...

Ngày tải lên: 09/08/2014, 01:21