A–Z of Haematology - part 4 ppt
A–Z of Haematology - part 4 ppt
... ex- pression in about a third of cases of acute leukaemia and chronic granulocytic leuk- aemia, particularly in blast crisis DDAVP 1-deamino-6-D-arginine vaso- pressin, desmopressin acetate D-dimer ... KIP2 INK4 family p16 INK4A CDKN2A at 9p21 p16(INK4A), CDK4 inhibitor, CDKN2 p15 INK4B CDKN2B at 9p21 p15(INK4B), CDK4B inhibitor p18 INK4C CDKN2C at 1p32 p18(INK4C) p19 INK4D CDKN2D at 19p1...
Ngày tải lên: 10/08/2014, 08:20
A–Z of Haematology - part 1 pptx
... Transferase FUT1 ABO H h A B O -2 -L-fucosyltransferase nil -3 -N-acetyl-D- galactosaminyltransferase nil -3 -D galactosyltransferase Figure 3 ABO antigens. The formation of ABO antigens: (a) formation of H antigen ... transformation of myelopro- liferative disorders, forming AML 1- EAP, AML1-EVI1 and AML-MDS1 • part of ETV6 to form a fusion gene, ETV6-AML1 (TEL-AML1),...
Ngày tải lên: 10/08/2014, 08:20
A–Z of Haematology - part 7 ppt
... central part of a bone composed of an anastomosing network of trabecular or cancellous bone (ii) the central part of the kidney (iii) the central part of a lymph node (iv) the central part of the ... at 11q23 • MLL-FBP17 in ins(11;9)(q23;q 34) inv(11)(q13q23) • MLL-CALM in inv(q 14, 2q23.1) • MLL-GPNH in t(11; 14) (q23;q 24) • MLL-AF17 in t(11;17)(q23;q21) • MLL-RARA in...
Ngày tải lên: 10/08/2014, 08:21
A–Z of Haematology - part 2 docx
... chromosome num- ber that is not 46 nor a multiple nor half of 46 aneuploidy presence of a clone of cells with a number of chromosomes which is not 46 nor a multiple nor half of 46 aneurysm a ... of severe asthma and anti-CD4 monoclonal antibodies have also been used in psoriasis CD4 is expressed on blast cells of many cases of T-lineage acute lympho- blastic leukaemia a...
Ngày tải lên: 10/08/2014, 08:20
A–Z of Haematology - part 3 pdf
... chain; the β chain of VLAs (very late activation antigens) including VLA-1 (CD49a/CD29), VLA-2 (CD49b/CD29), VLA-3 (CD49c/CD29) and VLA -4 (CD49d/CD29); VLA-2 is platelet glyco- protein IaIIa, a ... expressed on hairy cells 42 CD 24 HAE-C 01/13/2005 05:10PM Page 42 of cases of lymphoplasmacytoid lym- phoma and a quarter of cases of hairy cell leukaemia; the lack of expressio...
Ngày tải lên: 10/08/2014, 08:20
A–Z of Haematology - part 5 potx
... 113 Glucose ATP ADP Hexokinase Glucose-6-phosphate Fructose-6-phosphate Fructose-1,6-diphosphate Glyceraldehyde- 3-phosphate 1,3-biphosphoglycerate 3-phosphoglycerate 2-phosphoglycerate Phosphoenolpyruvate Pyruvate Lactate Dihydroxyacetone phosphate Haemoglobin Methaemoglobin ATP ADP Glucosephosphate ... is mutated in about 10% of cases of multiple myeloma and in about 10% of cases of...
Ngày tải lên: 10/08/2014, 08:20
A–Z of Haematology - part 6 pps
... hemizygosity HAE-H 01/13/2005 05:12PM Page 1 24 SCF HSC SCF FTL3L IL7 CLP T B NK LDC IL2 IL7 IL6 SCF IL2 SCF FLT3L IL3 IL4 IL6 GM-CSF SCF IL3 IL6 GM-CSF CMP IL3 GM-CSF G-CSF M-CSF IL3, GM-CSF, G-CSF IL3 GM-CSF M-CSF GFU- GM GFU- G GFU- M MDC IL3 IL5 SCF IL3 IL4 SCF IL3 IL4 SCF IL3,SCF, GM-CSF IL11,EPO IL3, GM-CSF IL11,EPO SCF, IL1, ... GM-CSF, G-CSF IL3 GM-CSF M-CSF GFU- GM GFU- G GFU- M MDC...
Ngày tải lên: 10/08/2014, 08:20
A–Z of Haematology - part 9 potx
... 210 Table 16 Some of the genetic causes of severe combined immunodeficiency. Defect Deficiency of Janus-associated kinase 3 Deficiency of common γ chain of receptors for IL-2, IL -4 , IL-7, IL-9 and IL ... rearrange- ment of the regions of an immunoglo- bulin or T-cell receptor gene (see Fig. 46 , p. 135) red cell an erythrocyte, a non-nucleated cell of the peripheral blood th...
Ngày tải lên: 10/08/2014, 08:21
A–Z of Haematology - part 10 doc
... activation of macrophages and for T-cell mediated cytotoxicity type 2 (Th2) helper T cell a CD4+ helper T cell that secretes interleukin -4 , interleukin-5, interleukin-6, interleukin-9, interleukin-10 ... in blast cells of 88% of cases of acute lym- phoblastic leukaemia and 97% of cases of acute myeloid leukaemia. Wolman’s disease an inherited meta- bolic disorder, a juvenile fo...
Ngày tải lên: 10/08/2014, 08:21
A Principles of Hyperplasticity Part 4 ppt
... Equation (4. 53) ij ij uw V wH (4. 55) u s w T w (4. 56) Equations (4. 54) (4. 56) are sufficient to establish the constitutive behaviour. For convenience of the derivation of incremental ... * g g ij ij ij y yywww wV wF wV (4. 40) 4. 14 Summary 75 The second potential is the specific mechanical dissipation, a function of state and the rate of change of int...
Ngày tải lên: 10/08/2014, 11:21