ANEMIAS AND OTHER RED CELL DISORDERS - PART 1 docx

... stepping. Chapter 024. Gait and Balance Disorders (Part 1) Harrison's Internal Medicine > Chapter 24. Gait and Balance Disorders Prevalence, Morbidity, and Mortality Gait and balance ... Among those 85 and older, the prevalence of gait abnormality approaches 40%. In epidemiologic studies, gait disorders are consistently identified as...

Ngày tải lên: 06/07/2014, 13:20

... cognition; an occipitotemporal network for face and object recognition; a limbic network for retentive memory; and a prefrontal network for attention and behavior. The numbers refer to the ... that intersect in Lateral (top) and medial (bottom) views of the cerebral hemispheres. The primary sensory and motor areas constitute 10% of the cerebral cortex. The rest...

Ngày tải lên: 06/07/2014, 13:20

... attention span. Otherwise, the failure of repetition becomes a reflection of the narrowed attention span rather Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 2) THE ... right handers and 60% of left handers, aphasia occurs only after lesions of the left hemisphere. In some individuals no hemispheric dominance for language can b...

Ngày tải lên: 06/07/2014, 13:20

... Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 3) The correspondence between individual deficits of language function and lesion location ... (Broca's and Wernicke's areas), and "disconnection" syndromes, which arise from lesions that interrupt the functional connectivity of these centers with each other...

Ngày tải lên: 06/07/2014, 13:20

... Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 4) Gestures and pantomime do not improve communication. The patient ... middle cerebral artery, and to the posterior temporal or angular branches in particular, is the most common etiology (Chap. 3 64). Intracerebral hemorrhage, severe head trauma, or neoplasm are other ... agita...

Ngày tải lên: 06/07/2014, 13:20

... Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 5) Conduction Aphasia Speech output is fluent but paraphasic, comprehension of spoken language is intact, and ... from other regions of the brain. Broca's and Wernicke's areas tend to be spared, but there is damage to the surrounding frontal, parietal, and temporal...

Ngày tải lên: 06/07/2014, 13:20

... musculature ("close the eyes," "stand up") is subserved by different pathways and may be intact in otherwise severely aphasic and apraxic patients. Patients with lesions of ... of the face and mouth. Limb apraxia encompasses apraxic deficits in movements of the arms and legs. Ideomotor apraxia is almost always caused by lesions in the left hemisphere and is...

Ngày tải lên: 06/07/2014, 13:20

... specific patterns described in Table 27-1. In a patient Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 7) Gerstmann's Syndrome The combination of acalculia ... Variations of melodic stress and intonation influence the meaning and impact of spoken language. For example, the two statements "He is clever." and...

Ngày tải lên: 06/07/2014, 13:20

... blood volume and red cell mass: Re-examination of 51 Cr and 12 5 I methods. Blood Cells Mol Dis 22 :16 9 18 6. 2 Greendyke RM. 19 63. Revised normal values for hemoglobin, hematocrit and erythrocyte count ... Reference and selected procedures for the quantitative determination of hemoglobin in blood; approved standard-third edition. NCCLS document H15-A3 (ISBN 1- 5 623 8-4...

Ngày tải lên: 10/08/2014, 08:20

... G6PD-deficient ery- throcytes: Possible cause of hemolysis and resistance to malaria. Blood 67 :33 1 33 3. 56 Roth EF, Jr, Raventos-Suarez C, Rinaldi A, Nagel RL. 19 83. Glucose-6-phosphate dehy- drogenase ... Plasmodium falciparum to glucose 6- phosphate dehydrogenase-deficient host red cells by production of parasite-encoded en- zyme. Nature 31 3:7 93 795. CHAPTER 7 IRON DEFICIENCY 1...

Ngày tải lên: 10/08/2014, 08:20

... Production Hepcidin - Interleukin 6 - Interleukin 1 TNF-α - Interferon-γ - The cytokines listed are the best characterized to date. Others will undoubtedly be uncovered. TABLE 7-9 KEY DIAGNOSTIC ... stages in red cell development, going from the CFU-E (colony forming unit- erythroid) to the mature erythrocyte. Erythropoietin promotes growth and maturation both of the...

Ngày tải lên: 10/08/2014, 08:20

... aplastic anemia: Risk factors and treatment results. Blood 73 :60 6 61 3. 16 Tsujimura H, Sakai C, Takagi T. 1999. Pure red cell aplasia complicated by angioim- munoblastic T -cell lymphoma: Humoral factor ... cells/μL reduce the risk of catastrophic bleeds, such as intracranial hemorrhage. ᭿ PURE RED CELL APLASIA Pure red cell aplasia reflects selective destruction of red...

Ngày tải lên: 10/08/2014, 08:20

... sideroblastic anemias demon- strate impaired heme production. 78 –80 Most commonly, the sideroblastic anemias are classified as hereditary or acquired conditions (Table 1 2-6 ). The hereditary forms ... the myelodysplastic disorders. 86 Hypothermia is a rare antecedent of sideroblastic anemia. 87 In contrast to the hereditary conditions, the acquired sider- oblastic anemias, partic...

Ngày tải lên: 10/08/2014, 08:20

... 20:3341–3346. 20 Bonkovsky, HL. 199 1. Iron and the liver. Am J Med 301:32–43. 21 Link G, Konijn AM, Hershko C. 199 9. Cardioprotective effect of alpha-tocopherol, ascor- bate, deferoxamine, and deferiprone: Mitochondrial ... dooms the G6PD-deficient erythrocytes. Heinz bodies also adhere to the red cell membrane where they disrupt architec- ture, promote oxidation and cross-linking...

Ngày tải lên: 10/08/2014, 08:20

... or red cell sensitization. 10 The drug induces red cell autoantibodies in 10 20% of patients after 4 or more months of use. These red cell antibodies are true autoantibodies directed against red ... malaria, 87–88sideroblastic anemias, 46, 221 acquired sideroblastic anemias vs. hereditary, 223 categories of, 223 disturbed heme metabolism and, 223 drug- and toxin-induce...

Ngày tải lên: 10/08/2014, 08:20