ANEMIAS AND OTHER RED CELL DISORDERS - PART 1 docx
Chapter 024. Gait and Balance Disorders (Part 1) docx
... stepping.
Chapter 024. Gait and Balance Disorders
(Part 1)
Harrison's Internal Medicine > Chapter 24. Gait and Balance Disorders
Prevalence, Morbidity, and Mortality
Gait and balance ...
Among those 85 and older, the prevalence of gait abnormality approaches
40%. In epidemiologic studies, gait disorders are consistently identified as...
Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 1) pdf
...
cognition; an occipitotemporal network for face and object recognition; a limbic
network for retentive memory; and a prefrontal network for attention and
behavior.
The numbers refer to the ... that intersect in
Lateral (top) and medial (bottom) views of the cerebral hemispheres.
The primary sensory and motor areas constitute 10% of the cerebral cortex.
The rest...
Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 2) pptx
... attention span. Otherwise, the
failure of repetition becomes a reflection of the narrowed attention span rather
Chapter 027. Aphasia, Memory Loss, and
Other Focal Cerebral Disorders
(Part 2)
THE ... right handers and 60% of left handers,
aphasia occurs only after lesions of the left hemisphere. In some individuals no
hemispheric dominance for language can b...
Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 3) pot
... Chapter 027. Aphasia, Memory Loss, and
Other Focal Cerebral Disorders
(Part 3)
The correspondence between individual deficits of language function and
lesion location ... (Broca's
and Wernicke's areas), and "disconnection" syndromes, which arise from lesions
that interrupt the functional connectivity of these centers with each other...
Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 4) doc
... Chapter 027. Aphasia, Memory Loss, and
Other Focal Cerebral Disorders
(Part 4)
Gestures and pantomime do not improve communication. The patient ... middle cerebral artery,
and to the posterior temporal or angular branches in particular, is the most
common etiology (Chap. 3 64). Intracerebral hemorrhage, severe head trauma, or
neoplasm are other ... agita...
Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 5) pot
...
Chapter 027. Aphasia, Memory Loss, and
Other Focal Cerebral Disorders
(Part 5)
Conduction Aphasia
Speech output is fluent but paraphasic, comprehension of spoken language
is intact, and ... from other regions of the brain. Broca's and Wernicke's areas tend to be
spared, but there is damage to the surrounding frontal, parietal, and temporal...
Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 6) doc
...
musculature ("close the eyes," "stand up") is subserved by different pathways and
may be intact in otherwise severely aphasic and apraxic patients. Patients with
lesions of ... of the face and mouth. Limb apraxia
encompasses apraxic deficits in movements of the arms and legs. Ideomotor
apraxia is almost always caused by lesions in the left hemisphere and is...
Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 7) doc
... specific patterns described in Table 27-1. In a patient
Chapter 027. Aphasia, Memory Loss, and
Other Focal Cerebral Disorders
(Part 7)
Gerstmann's Syndrome
The combination of acalculia ... Variations of melodic stress and intonation influence the meaning and
impact of spoken language. For example, the two statements "He is clever." and...
ANEMIAS AND OTHER RED CELL DISORDERS - PART 1 docx
... blood volume and red
cell mass: Re-examination of
51
Cr and
12 5
I methods. Blood Cells Mol Dis 22 :16 9 18 6.
2
Greendyke RM. 19 63. Revised normal values for hemoglobin, hematocrit and erythrocyte
count ... Reference and selected procedures for the quantitative determination of
hemoglobin in blood; approved standard-third edition. NCCLS document H15-A3 (ISBN
1- 5 623 8-4...
ANEMIAS AND OTHER RED CELL DISORDERS - PART 3 ppt
... G6PD-deficient ery-
throcytes: Possible cause of hemolysis and resistance to malaria. Blood 67 :33 1 33 3.
56
Roth EF, Jr, Raventos-Suarez C, Rinaldi A, Nagel RL. 19 83. Glucose-6-phosphate dehy-
drogenase ... Plasmodium falciparum to glucose 6-
phosphate dehydrogenase-deficient host red cells by production of parasite-encoded en-
zyme. Nature 31 3:7 93 795.
CHAPTER 7 IRON DEFICIENCY 1...
ANEMIAS AND OTHER RED CELL DISORDERS - PART 4 pot
... Production
Hepcidin -
Interleukin 6
-
Interleukin 1
TNF-α -
Interferon-γ -
The cytokines listed are the best characterized to date. Others will undoubtedly be uncovered.
TABLE 7-9
KEY DIAGNOSTIC ... stages in red cell development, going from the CFU-E (colony forming unit-
erythroid) to the mature erythrocyte. Erythropoietin promotes growth and maturation both of the...
ANEMIAS AND OTHER RED CELL DISORDERS - PART 6 pps
... aplastic anemia: Risk factors and treatment results. Blood
73 :60 6 61 3.
16
Tsujimura H, Sakai C, Takagi T. 1999. Pure red cell aplasia complicated by angioim-
munoblastic T -cell lymphoma: Humoral factor ... cells/μL reduce the risk of catastrophic
bleeds, such as intracranial hemorrhage.
PURE RED CELL APLASIA
Pure red cell aplasia reflects selective destruction of red...
ANEMIAS AND OTHER RED CELL DISORDERS - PART 7 doc
... sideroblastic anemias demon-
strate impaired heme production.
78 –80
Most commonly, the sideroblastic anemias are
classified as hereditary or acquired conditions (Table 1 2-6 ). The hereditary forms ... the myelodysplastic disorders.
86
Hypothermia is a rare antecedent
of sideroblastic anemia.
87
In contrast to the hereditary conditions, the acquired sider-
oblastic anemias, partic...
ANEMIAS AND OTHER RED CELL DISORDERS - PART 9 ppt
... 20:3341–3346.
20
Bonkovsky, HL. 199 1. Iron and the liver. Am J Med 301:32–43.
21
Link G, Konijn AM, Hershko C. 199 9. Cardioprotective effect of alpha-tocopherol, ascor-
bate, deferoxamine, and deferiprone: Mitochondrial ... dooms the G6PD-deficient erythrocytes.
Heinz bodies also adhere to the red cell membrane where they disrupt architec-
ture, promote oxidation and cross-linking...
ANEMIAS AND OTHER RED CELL DISORDERS - PART 10 docx
... or red cell sensitization.
10
The drug induces red cell autoantibodies in
10 20% of patients after 4 or more months of use. These red cell antibodies are
true autoantibodies directed against red ... malaria,
87–88sideroblastic anemias,
46, 221
acquired sideroblastic anemias vs.
hereditary, 223
categories of, 223
disturbed heme metabolism and, 223
drug- and toxin-induce...