Báo cáo y học: " Estimating the impact of expanded access to antiretroviral therapy on maternal, paternal and double orphans in sub-Saharan Africa, 2009-2020" ppt
Báo cáo y học: "Demonstrating the benefit of medical emergency teams (MET) proves more difficult than anticipated"
... larger than anticipated. These factors significantly reduced the power of the study. Based on their findings, the authors estimate that more than 100 hospitals would be needed to show the 30% ... a clear benefit for MET may take longer than the 6-month period of this study. Contamination of control hospitals also may have been an issue. Though they did not receive the study-based educational ... goal of identifying and treating patients early in the course of their illness is preferable to waiting until more serious signs and symptoms have developed. Certainly, at the University of...
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Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf
... 2002 Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase Konstantinos Mavromatis1,*, Iason Tsigos2,*, Maria Tzanodaskalaki2, Michael Kokkinidis1,3and Vassilis ... the active site of the psychrophilic alkaline phosphatase from the AntarcticTable 1. Enzymatic and thermodynamic parameters of the psychrophilic alkaline phosphatase and mutants. Reported values ... role in the cold adaptation of the enzyme.Keywords: alkaline phosphatase; psychrophiles; cold adaptation; structural flexibility; glycine clusters. Cold adapted enzymes, produced by organisms living...
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Tài liệu Báo cáo Y học: Dissecting the effect of trifluoroethanol on ribonuclease A Subtle structural changes detected by nonspecific proteases ppt
... however, an appreciable effect on the tertiaryand secondary structure was found only at higherconcentrations of the solvent [13]. At low concentrations of trifluoroethanol, the propagation of helical ... differences in the changes of the tertiary and secondary structures are reflected in the activity of RNase A, its activity towards cCMP was measured as a function of the concentration of trifluoroethanol ... lL0.1MNaOH.Fig. 1. Activity of proteinase K as a function of the concentration of trifluoroethanol. Activity of proteinase K was determined withN-succinyl-Ala-Ala-Ala-p-nitroanilide as substrate at 25 Casdescribed...
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Báo cáo Y học: Membrane embedded location of Na+ or H+ binding sites on the rotor ring of F1F0 ATP synthases ppt
... intrinsic rotor channels. The common membrane embedded location of the binding site of ATP synthases suggest a commonmechanism for ion transfer across the membrane. Keywords: coupling ion binding ... with cGlu65 of the ATP synthase of I. tartaricus or cAsp61 of the ATP synthase of E. coli and is therefore suitable for fluorescenceinvestigations.Reconstitution of the E. coli ATP synthaseinto ... into1 mL of the assay mixture.Determination of ATP hydrolyzing activity The coupled enzyme assay was used to determine ATP hydrolyzing activity of the different samples [30].Preparation of lipid...
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Báo cáo khoa học: "Evaluating the Impact of Coder Errors on Active Learning" ppt
... thorough evaluation of the impact of annotation noise on AL. We simulatedifferent types of coder errors and assess the effect on the learning process. We propose a method to de-tect inconsistencies ... research on the impact of annota-tion noise in the context of supervised classification.Section 3 describes the experimental setup of oursimulation study and presents results. In Section 4we ... answer these questions we look at one fold of the ALbias data with 10% of noise. In 1,200 AL it-erations the system rejected 116 instances (Table 3). The major part of the rejections was due to the...
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Báo cáo Y học: Probing the role of glutamic acid 139 of Anabaena ferredoxin-NADP+ reductase in the interaction with substrates pptx
... [24]. In the present study, furthercharacterization of E139D, E139K and E139Q FNR formshas been carried out in order to elucidate the role of E139not only in the protein interaction and ET with ... side-chain [22]. Such observation also suggested that in E301A FNR the side-chain of E139 might in uence the properties of the flavin, assuming some of the functionscarried out by E301 in the wild-type ... (0.22 A˚)oftheCa backbone. Only slight differencesare observed in the loop starting at Y1 04 and ending atV113 near the region interacting with the adenine moiety of FAD, but they are not significant...
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Báo cáo Y học: Beyond the ABCs of CKC and SCC Do centromeres orchestrate sister chromatid cohesion or vice versa? potx
... FEBS 2002 MINIREVIEW Beyond the ABCs of CKC and SCC Do centromeres orchestrate sister chromatid cohesion or vice versa? Pamela B. Meluh1 and Alexander V. Strunnikov21Memorial Sloan-Kettering ... Laboratory of Mechanism and Regulation of Mitosis, New York, USA;2Unit of Chromosome Structure and Function, NIH, NICHD, Laboratory of Gene Regulation and Development, Bethesda, MD, USA The ... nature of centromeric chromatin, the dynamics and regulation of sister chromatid cohesion, and the relationship between the two.Keywords: centromere; kinetochore; CENP-A; histone;methylation;...
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báo cáo sinh học:" Assessing the impact of a new health sector pay system upon NHS staff in England" pot
... pre-existing system capable of evaluating all of the jobs covered. The new pay spines are divided into nine pay bands, and staff covered by Agenda for Change were assimilated on toone of these pay bands ... difficult to assess impact andvariations in impact across the NHS. While the pay system implemented in the NHS wasdesigned for the characteristics of that health care organi-zation, there are some ... higher pay andprices – mainly pay increases under Agenda for Changeand for medical staff. The implementation costs for the new pay system have been calculated as a cumulativeadditional cost of...
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Báo cáo y học: "Predicting the future of anti-tumor necrosis factor therapy" potx
... informa-tive sets of genes whose expression changes during therapyEditorialPredicting the future of anti-tumor necrosis factor therapyCornelis L VerweijDivision of Inflammatory Disease Profiling, ... costs for therapy, there isa strong need to make predictions on success before the start of therapy. In the current issue of Arthritis Research & Therapy,Hueber and colleagues become the first ... Essentially, twophases of unresponsiveness might be identified: a primaryphase directly after the start of treatment and a secondaryphase that develops in initial responders during the course of therapy....
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Báo cáo y học: "A feasibility study of immediate versus deferred antiretroviral therapy in children with HIV infectio" ppt
... purposes)AIDS Research and Therapy Open AccessResearchA feasibility study of immediate versus deferred antiretroviral therapy in children with HIV infectionJintanat Ananworanich*1,2, Pope ... Predictive value of quantitative plasma HIV RNA and CD4+ lymphocyte count in HIV- infectedinfants and children. Jama 1998, 279(10):756-761.10. Antiretroviral therapy of HIV infection in infants and ... the HIV- NAT 010 Study Team - Not@valid.com* Corresponding author AbstractObjective: To evaluate the feasibility of a large immediate versus deferred antiretroviral therapy (ART) study in children. Methods:...
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Báo cáo y học: " Estimating the impact of expanded access to antiretroviral therapy on maternal, paternal and double orphans in sub-Saharan Africa, 2009-2020" ppt
... al.: Estimating the impact of expanded access to antiretroviral therapy on maternal, paternal and double orphans in sub-Saharan Africa, 2009-2020. AIDS Research and Therapy 2011 8:13.Submit your ... tion model may have also over-estimated the number of orphans in curred and averted in the sub-Saharan African countries under study.This study only indirectly considered the impact of non-adherence ... contributionsAA conceived the study design, contributed to the demographic modelingmethods, and wrote the first draft of the manuscript. CA and MJ ran the demographic projection software and...
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Báo cáo y học: "Measuring the impact of apnea and obesity on circadian activity patterns using functional linear modeling of actigraphy data" pps
... 9:11http://www.jcircadianrhythms.com/content/9/1/11Page 5 of 10 RESEARCH Open AccessMeasuring the impact of apnea and obesity on circadian activity patterns using functional linear modeling of actigraphy ... ResultsWeapplyFLMtomeasuretheimpactofapneaandBMI on subject circadian activity patterns and test the null hypothesis that circadian activity patterns are the same regardless of apnea and BMI values. The alterna-tive hypothesis is that apnea, ... activity in the afternoon, and another group has areversed pattern with the same magnitude of activity, low activity in the morning and high activity in the afternoon, their average activity may...
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Báo cáo y học: " Disrupting the rhythm of depression using Mobile Cognitive Therapy for recurrent depression: randomized controlled trial design and protocol" ppt
... et al.: Disrupting the rhythm of depression using Mobile Cognitive Therapy for recurrent depression: randomized controlled trial design and protocol. BMC Psychiatry 2011 11:12.Submit your next ... 11:12http://www.biomedcentral.com/1471-244X/11/12Page 9 of 9 STUDY PROT O C O L Open Access Disrupting the rhythm of depression using Mobile Cognitive Therapy for recurrent depression: randomized controlled trial design and protocolClaudi ... participantunderstands all aspects of the trial. If they agree toenter the trial, they complete a copy of the consentform and s end it to the researcher. We remind partici-pants that they can withdraw...
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Báo cáo y học: " Potential therapeutic effects of branched-chain amino acids supplementation on resistance exercise-based muscle damage in humans" pps
... followed by evidences of effects of BCAA supplementation on RE-induced muscle damage in humans. Discussion Cellular responses and biochemical markers of muscle damage The damage of muscle ... Bajotto G, Sato J: Effects of squat exercise and branched-chain amino acid supplementation on plasma free amino acid concentrations in young women. J Nutr Sci Vitaminol (Tokyo) 2009, 55(3):288-291. ... potential intervention [3, 4]. It is known that these amino acids, particularly leucine, have anabolic potential by stimulating the initiation of protein translation [5], possibly suppressing/attenuating...
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Báo cáo y học: "Estimating the number of children exposed to parental psychiatric disorders through a national health survey" doc
... treatment – and who therefore may be at greater risk– would fall through the cracks.Since estimates of the number of children exposed to parental MI in Canada are not available, the aim of ... Psychiatry, University of Toronto, Toronto, ON, Canada and 7Centre for Addiction and Mental Health, Health Systems Research and Consulting Unit, Toronto, ON, CanadaEmail: Diego G Bassani* - bassanid@smh.toronto.on.ca; ... CentralPage 1 of 7(page number not for citation purposes)Child and Adolescent Psychiatry and Mental Health Open AccessResearchEstimating the number of children exposed to parental psychiatric...
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