Báo cáo y học: " The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage" potx
Báo cáo khoa học: The Y42H mutation in medium-chain acyl-CoA dehydrogenase, which is prevalent in babies identified by MS/MS-based newborn screening, is temperature sensitiv pptx
... 2004 The MCAD Y42H mutation is temperature sensitive (Eur. J. Biochem. 271) 4063 The Y42H mutation in medium-chain acyl-CoA dehydrogenase, which is prevalent in babies identified by MS/MS-based newborn screening, ... observed,indicating that the temperature- induced change in the foldof the structure is indistinguishable between the threeproteins at this protein concentration. Furthermore, this temperature- induced ... overcome by increasing the amount ofchaperonins or by lowering the culture temperature when the recombinant protein is expressed in Escherichia coli[21,22]. Similarly, many of the other disease-causing...
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Báo cáo y học: "The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease" pot
... expression of Crabp2 is generally linked to activa-tion of the retinoid pathway either directly, because expression of Crabp2 is regulated by retinoic acid, or indirectly, because increased CRABP2 ... http://arthritis-research.com/content/11/1/R14Page 1 of 9(page number not for citation purposes)Vol 11 No 1Research articleThe retinoic acid binding protein CRABP2 is increased in murine models of degenerative ... OA joint four weeks post-surgery [30]. Crabp2 is regulated by retinoic acid and is often induced upon activation of this path-way [33]. We were interested in confirming these findings anddetermining...
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Báo cáo y học: "Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosu" pptx
... logistic regression model. This finding is in line with a previous study on major infections in SLE patients in the Hopkins Lupus Cohort [32].Renal insufficiency is a possible risk factor for infections. ... study functional MBL in SLE patients at risk for infection. Functional activity of the MBL pathway in serum not only is determined by mutations in the gene encoding MBL, but also is influenced by ... hydroxychloroquine use and the occurrence of major infections. This finding might be explained by the predominantuse of hydroxychloroquine in the treatment of patients with mild lupus disease activity and...
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Báo cáo y học: "The devil’s in the details" pdf
... from the government to actually fund that agency or program. In the absence of an appropriation, agencies must fi nd the money they need to satisfy an authorization by taking it away from other ... from the individual research grant pool would turn that cliff into an abyss. ere are various alternatives for ‘fi nding’ the money that the community should urge the NIH Director to look into. ... received the unqualifi ed support of the biological science community, chiefl y because they saw it as taking money and attention away from important fundamental research and channeling it into...
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Báo cáo y học: " The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage" potx
... hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage? AIDSResearch and Therapy 2011 8:7.Wiesmann et al. AIDS Research and Therapy 2011, 8:7http://www.aidsrestherapy.com/content/8/1/7Page ... 8:7http://www.aidsrestherapy.com/content/8/1/7Page 3 of 9 SHOR T REPOR T Open Access The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and ... gene mutation L76V showincreased susceptibility for Atazanavir and SaquinavirAt first, the impact of L76V on ATV- and SQV-resistance characteristics was assessed before and afterestablishment...
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Báo cáo y học: " The natural history of West Nile virus infection presenting with West Nile virus meningoencephalitis in a man with a prolonged illness: a case report" doc
... CAS E REP O R T Open Access The natural history of West Nile virus infection presenting with West Nile virus meningoencephalitis in a man with a prolonged illness: a case reportShraddha Mainali1, ... this article as: Mainali et al.: The natural history of West Nile virus infection presenting with West Nile virus meningoencephalitis in a man with a prolo nged illness: a case report. Journal of ... identified in the United States of America, where it appeared during an outbreak of natu-rally acquired meningitis and encephalitis in the NewYork City area [3].WNV infection typically peaksinlateJulythroughearly...
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Báo cáo y học: "The patient perspective in research on major depression Pim Cuijpers" pps
... medication, treatment and coping with the daily problems of having depression. Commentary: The patient perspective in research on major depression In the past decades, thousands of studies have examinedthe ... or not. Research from the patients’ perspective is also necessary to meet thecurrently unmet informat ion needs of patients, including information about the nature and causes of depression, stigma, ... N TAR Y Open AccessThe patient perspective in research on major depression Pim CuijpersAbstractAlthough thousands of studies have examined the genetics, epidemiology, etiology, biology, treatment...
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Báo cáo y học: " The working alliance in a randomized controlled trial comparing online with face-to-face cognitive-behavioral therapy for depression" pptx
... evidence for a comparably strong working alliance in online settings as in face-to-face therapy. Cook and Doyle [18], for example, reported results for an online sample to be comparable with normative ... factors in the online setting. In face-to face therapy, the quality of the working alliance explains variance in treatment outcome. However, little is yet known about the impact of the working ... article as it appeared upon acceptance. Fully formattedPDF and full text (HTML) versions will be made available soon. The working alliance in a randomized controlled trial comparing online with face-to-face...
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Báo cáo y học: "A novel mutation in the ADA gene causing severe combined immunodeficiency in an Arab patient: a case report" ppt
... mutation in the ADA gene causing severe combined immunodeficiency in an Arab patient: a case reportAli Hellani1, Nidal Almassri2and Khaled K Abu-Amero3*Addresses:1PGD Laboratory, Saad ... of adenosine deaminase mutation in an Arab patient with severe combined immunodeficiency due to a novel pathogenic mutation in the adenosine deaminase gene. IntroductionHuman severe combined immunodeficiency ... Specialist Hospital, Al-khobar, 31952 Saudi Arabia,2Pathology and Laboratory Medicine Department,Saad Specialist Hospital, Al-khobar, 31952 Saudi Arabia and3Molecular Genetics Laboratory,...
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Báo cáo y học: " The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis" pps
... fibrosis is increased in CAT2-deficientmice as measured by the whole lung hydroxyproline assay[8]. Interestingly, this baseline fibrosis is not evident his-tologically by trichrome staining, ... would be involved in lung fibrosis.This is based on the following: 1) CAT2 is upregulated in bleomycin -induced pulmonary fibrosis [19] and 2) argi-nase metabolizes arginine to ornithine, which ... 9Conclusions In summary, we have described a pathway (involvingCAT2 and arginine homeostasis) not previously exam-ined in the context of lung inflammation and fibrosis. Wefind that while CAT2 is highly...
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Báo cáo y học: " The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro" doc
... properly cited.Research The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitroJinwoo Ahn1, In- Ja L Byeon1, ... NusA -HuR binds a synthetic RNA template that contains AREs (Fig. 2C), indicatingthat the fusion does not interfere with the RNA binding activity of HuR. Probing the interaction between HIV-1 RT and ... article as: Ahn et al., The RNA binding protein HuR does not inter-act directly with HIV-1 reverse transcriptase and does not affect reverse tran-scription in vitro Retrovirology 2010, 7:40 Ahn...
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Báo cáo y học: "The health related quality of life of people living with HIV/AIDS in sub-Saharan Africa - a literature review and focus group study" pot
... health related quality of life of people living with HIV/AIDS in sub-Saharan Africa - a literature review and focus group study Cost Effectiveness and Resource Allocation 2010, 8:5 Robberstad and ... repro-duction in any medium, provided the original work is properly cited.ResearchThe health related quality of life of people living with HIV/AIDS in sub-Saharan Africa - a literature review and focus ... presented in Figure 1.The remaining 29 research articles contain varioustypes of health related quality of life evidence for people living with HIV/AIDS in sub-Saharan Africa. The major-ity of these...
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Báo cáo y học: " The connection domain in reverse transcriptase facilitates the in vivo annealing of tRNALys3 to HIV-1 genomic RNA" potx
... similarly in vivo is notknown.Alternatively, the RT connection domain may undergointeractions with Gag that may result in placing the tRNALys3 bound to the thumb domain in RT closer to either ... viral packaging. tRNALys3 incorpora-tion into HIV-1 is not affected by deletion of the IN domain in GagPol, nor by further deletion of the RNaseHtRNA Lys3 annealing to viral genomic RNAFigure ... in tRNALys3 annealing onto the viral RNA, independent of its role in the packag-ing of tRNALys3 into the virion. We present data hereinindicating that the RT connection domain, while non-essential...
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Báo cáo y học: "Serum resistin levels in critically ill patients are associated with inflammation, organ dysfunction and metabolism and may predict survival of non-septic patients" potx
... 4Association of serum resistin with severity of disease and survival in critically ill patientsAssociation of serum resistin with severity of disease and survival in critically ill patients. (a) Serum resistin ... sepsis. In critically ill patients, hyperinsulinemia and hyperglycemia are common findings and predictive for an unfavorable outcome[3,21]. The mechanisms of insulin resistance in critically ill patients ... endocrinologic role of resistin in humanglucose metabolism and insulin resistin, unlike the findings in murine models, is still unclear. In our cohort as well as in a priorstudy of septic patients...
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Báo cáo y học: "Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsis" pptx
... H, Gnaiger E, Elmer E: Sepsisinduces platelet mitochondrial uncoupling and a gradual increase in respiratory capacity that is negatively associated with clinical outcome. Crit Care 2010, 14:R214.16. ... Journal Of Physiology 2004,286:R491-497.doi:10.1186/cc9337Cite this article as: Sjövall et al.: Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in ... of 11 RESEARC H Open AccessTemporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsisFredrik Sjövall1,2*, Saori Morota1,...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnbáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngbáo cáo y tế học đường cuối nămNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ