Báo cáo y học: " The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage" potx

... 2004 The MCAD Y42H mutation is temperature sensitive (Eur. J. Biochem. 271) 4063 The Y42H mutation in medium-chain acyl-CoA dehydrogenase, which is prevalent in babies identified by MS/MS-based newborn screening, ... observed, indicating that the temperature- induced change in the fold of the structure is indistinguishable between the t...

Ngày tải lên: 07/03/2014, 16:20

... expression of Crabp2 is generally linked to activa- tion of the retinoid pathway either directly, because expression of Crabp2 is regulated by retinoic acid, or indirectly, because increased CRABP2 ... http://arthritis-research.com/content/11/1/R14 Page 1 of 9 (page number not for citation purposes) Vol 11 No 1 Research article The retinoic acid binding protein...

Ngày tải lên: 09/08/2014, 01:22

... logistic regression model. This finding is in line with a previous study on major infections in SLE patients in the Hopkins Lupus Cohort [32]. Renal insufficiency is a possible risk factor for infections. ... study functional MBL in SLE patients at risk for infection. Functional activity of the MBL pathway in serum not only is determined by mutations in th...

Ngày tải lên: 09/08/2014, 08:23

... from the government to actually fund that agency or program. In the absence of an appropriation, agencies must fi nd the money they need to satisfy an authorization by taking it away from other ... from the individual research grant pool would turn that cliff into an abyss.  ere are various alternatives for ‘fi nding’ the money that the community should urge the NIH Direct...

Ngày tải lên: 09/08/2014, 20:21

... hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage? AIDS Research and Therapy 2011 8:7. Wiesmann et al. AIDS Research and Therapy 2011, 8:7 http://www.aidsrestherapy.com/content/8/1/7 Page ... 8:7 http://www.aidsrestherapy.com/content/8/1/7 Page 3 of 9 SHOR T REPOR T Open Access The L76V mutation in HIV-1 p...

Ngày tải lên: 10/08/2014, 05:22

... CAS E REP O R T Open Access The natural history of West Nile virus infection presenting with West Nile virus meningoencephalitis in a man with a prolonged illness: a case report Shraddha Mainali 1 , ... this article as: Mainali et al.: The natural history of West Nile virus infection presenting with West Nile virus menin...

Ngày tải lên: 11/08/2014, 00:23

... medication, treatment and coping with the daily problems of having depression. Commentary: The patient perspective in research on major depression In the past decades, thousands of studies have examined the ... or not. Research from the patients’ perspective is also necessary to meet the currently unmet informat ion needs of patients, including information about the natu...

Ngày tải lên: 11/08/2014, 15:22

... evidence for a comparably strong working alliance in online settings as in face-to-face therapy. Cook and Doyle [18], for example, reported results for an online sample to be comparable with normative ... factors in the online setting. In face-to face therapy, the quality of the working alliance explains variance in treatment outcome. However, litt...

Ngày tải lên: 11/08/2014, 16:21

... mutation in the ADA gene causing severe combined immunodeficiency in an Arab patient: a case report Ali Hellani 1 , Nidal Almassri 2 and Khaled K Abu-Amero 3 * Addresses: 1 PGD Laboratory, Saad ... of adenosine deaminase mutation in an Arab patient with severe combined immunodeficiency due to a novel pathogenic mutation in the adenosine de...

Ngày tải lên: 11/08/2014, 17:21

... fibrosis is increased in CAT2-deficient mice as measured by the whole lung hydroxyproline assay [8]. Interestingly, this baseline fibrosis is not evident his- tologically by trichrome staining, ... would be involved in lung fibrosis. This is based on the following: 1) CAT2 is upregulated in bleomycin -induced pulmonary fibrosis [19] and 2) argi- nase metabolizes argi...

Ngày tải lên: 12/08/2014, 11:22

... properly cited. Research The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro Jinwoo Ahn 1 , In- Ja L Byeon 1 , ... NusA -HuR binds a synthetic RNA template that contains AREs (Fig. 2C), indicating that the fusion does not interfere with the RNA bindin...

Ngày tải lên: 12/08/2014, 23:23

... health related quality of life of people living with HIV/AIDS in sub-Saharan Africa - a literature review and focus group study Cost Effectiveness and Resource Allocation 2010, 8:5 Robberstad and ... repro- duction in any medium, provided the original work is properly cited. Research The health related quality of life of people l...

Ngày tải lên: 13/08/2014, 11:22

... similarly in vivo is not known. Alternatively, the RT connection domain may undergo interactions with Gag that may result in placing the tRNA Lys3 bound to the thumb domain in RT closer to either ... viral packaging. tRNA Lys3 incorpora- tion into HIV-1 is not affected by deletion of the IN domain in GagPol, nor by further deletion of the RNaseH tRNA...

Ngày tải lên: 13/08/2014, 13:20

... 4 Association of serum resistin with severity of disease and survival in critically ill patientsAssociation of serum resistin with severity of disease and survival in critically ill patients. (a) Serum resistin ... sepsis. In critically ill patients, hyperinsulinemia and hyperglycemia are common findings and predictive for an unfavorable out...

Ngày tải lên: 13/08/2014, 16:21

... H, Gnaiger E, Elmer E: Sepsis induces platelet mitochondrial uncoupling and a gradual increase in respiratory capacity that is negatively associated with clinical outcome. Crit Care 2010, 14:R214. 16. ... Journal Of Physiology 2004, 286:R491-497. doi:10.1186/cc9337 Cite this article as: Sjövall et al.: Temporal increase of platelet mitochondrial respiration is...

Ngày tải lên: 14/08/2014, 07:21