Báo cáo y học: " Nef-specific CD45RA+ CD8+ T cells secreting MIP-1β but not IFN-γ are associated with nonprogressive HIV-1 infection" ppsx
Báo cáo y học: " Nef-specific CD45RA+ CD8+ T cells secreting MIP-1β but not IFN-γ are associated with nonprogressive HIV-1 infection" ppsx
... specific CD8+ T cells with respect to the non-structural HIV-1 proteins Nef and Tat. Indeed, these two nonstructural proteins are known to strongly influence HIV-1 replication, pathoge- nicity and the ... PR and ART-treated patients. With this setting, we identified a novel population of CD8+ T cells associated with non- progressive HIV-1 infection. CD45RA+ IFN-...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: " Characteristics of CD8+ T cell subsets in Chinese patients with chronic HIV infection during initial ART" doc
... subsets during early period of ART have not been fully studied. Methods: Twenty-one asymptomatic treatment-naive HIV-infected patients with CD4 T+ cells less than 350 cells/ μl were enrolled in the ... cell subsets during antiretroviral treatment (ART). However, the changes of CD8+ T cell subsets in early period of ART have not been fully studied yet. Here, in our study, we inve...
Ngày tải lên: 10/08/2014, 05:22
Báo cáo y học: "Nature of Regulatory T Cells in the Context of Allergic Disease." ppsx
... allergen with the immune system starts with handling of it by the antigen-presenting cells, mainly dendritic cells (DCs), which process antigenic material and present it on its surface to other cells ... with the allergen within the gastrointestinal tract, where immune tolerance is the natural outcome. Freshly isolated oral LCs expressed significantly higher amounts of major histoc...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritis" ppsx
... CD4 + CD25 + regulatory T cells but are resistant to PGIA It has been shown that CD28–B7 interaction is essential for the homeostasis of the CD4 + CD25 + regulatory T cells that control autoimmune diabetes ... proliferate in response to proteoglycan stimulation in vitro, albeit at a rate lower than that in wild-type T cells, which is consistent with the report by Oliveira-dos...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Role of regulatory T cells in experimental arthritis and implications for clinical use" potx
... CD4 + CD25 + Treg can prevent the induction of autoimmunity but cannot ‘cure’ animals with ongoing autoimmunity. Thus it seems that the thresholds to control induction or progression (therapeutic action) ... accumulation in the inflamed joints, thus excluding the possibility that the lack of therapeutic activity was due to the inability of CD4 + CD25 + Treg to migrate into the inflamed ti...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: " High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis" pot
... is intimately associated with the HLA susceptibility locus. Shared epitope alleles are common in the Caucasian population but they are strongly associated with RA, along with the development of ... according to the susceptibility of thymocytes to death and the capacity of the T- cell receptor (TCR) and downstream pathways to transmit an activation signal. Moreover, the effici...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Apoptotic cell-mediated suppression of streptococcal cell wall-induced arthritis is associated with alteration of macrophage function and local regulatory T-cell increase: a potential cell-based therapy" ppsx
... efficient to induce and sustain SCW inflammation. Indeed, apoptotic cell injection acts in two different ways. First, apoptotic cells together with phagocytes that digest apoptotic cells in a very ... environment has been attributed to apoptotic cells themselves, apoptotic cell uptake by phagocytes as well as a less sensibility of phagocytes capturing apoptotic bodies to activation. T...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Transition of healthy to diseased synovial tissue in rheumatoid arthritis is associated with gain of mesenchymal/fibrotic characteristics" pdf
... 5'-CGTGTTGCCCCTGAAGAGCAT-3' 5'-ACCGCCTGGATAGCCACATACA-3' TLH 5'-TTAAAGGAAAGACACTCCGATCAGAGATGA-3' 5'-AATGTTTCCGGAGTAGGGGAGTCTTTTT-3' β 2 M 5'-TCTTGTACTACACTGAATTCACCCCCACTGA-3' ... mesenchymal pheno- type plays an important role in disease pathology, as it alters not only the phenotype, but also the migratory potential of the cells. Altho...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Anti-cyclic citrullinated peptide antibodies in primary Sjögren syndrome may be associated with non-erosive synovitis" ppt
... evaluated at the time of the anti-CCP analysis. Patients with at least one erosion were excluded from the study. Statistical analysis The data were statistically analysed by means of R software, version ... particularly in patients with the concomi- tant presence of IgM RF. Competing interests The authors declare that they have no competing interests. Authors' contributions FA and PS...
Ngày tải lên: 09/08/2014, 10:23
báo cáo hóa học: " Low ficolin-3 levels in early follow-up serum samples are associated with the severity and unfavorable outcome of acute ischemic stroke" pptx
... by the observation that ficolin-3 has the highest concentration and the greatest complement- activating capacity among the lectin pathway initiators [45]. Complement activation is one of the ... stated otherwise. Results The concentrations of the proteins of the lectin pathway and CRP in the sera of patients with ischemic stroke, as compared to healthy controls and patient controls...
Ngày tải lên: 19/06/2014, 22:20