Báo cáo y học: " Effects of CYP2B6 G516T polymorphisms on plasma efavirenz and nevirapine levels when co-administered with rifampicin in HIV/TB co-infected Thai adults" ppt

... G516T polymorphisms on plasma efavirenz and nevirapine concentrations when co-administered with rifampicin in HIV/TB co-infected Thai adults. Conclusions: CYP2B6- TT genotype had impact on plasma efavirenz ... Uttayamakul et al.: Effects of CYP2B6 G516T polymorphisms on plasma efavirenz and nevirapine levels when co-administered...

Ngày tải lên: 10/08/2014, 05:21

... Recommendations of accu- mulating at least 30 minutes, above one’s usual activity, of moderate-intensity physical activity five to seven days a week by integrating short bouts of activity into the day, ... often substantially hampers day-to-day functioning and is a primary cause of disability [5]. Even with the recent Food and Drug Administration approval of medications to tre...

Ngày tải lên: 12/08/2014, 12:20

... effect. In addition, the induction of injury was performed in anaesthetised healthy pigs. Thus, the physiological response to such things as pain and inflam- mation may have additional effects on ... manifold influence on the coagulation system, inflammatory responses and organ function. Our model of a combination of hydroxyethyl- starch and crystalloid represents the cu...

Ngày tải lên: 13/08/2014, 20:21

... main- tained till the early morning and then decreases again rap- idly to the extremely low concentration typical of the daytime [7,8]. The increase in melatonin concentration might occur in ... night increase in blood melatonin level as a direct effect and possibly delay the circadian system that drives the mela- tonin secretion rhythm and sleep-wake cycle. Effects of light...

Ngày tải lên: 10/08/2014, 09:20

... 8:25 http://www.journal-inflammation.com/content/8/1/25 Page 7 of 7 RESEARCH Open Access Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts Linnéa Asp 1 , Anne-Sofie Johansson 1 , Amandeep ... studies of disease-related abnormalities in the kynurenine pathway of tryptophan degradation. Keywords: human, fibroblast, ky...

Ngày tải lên: 11/08/2014, 03:20

... abnormalities in the kynurenine pathway of tryptophan degradation. Keywords: human, fibroblast, kynurenine pathway, gene expression, cytokine Introduction The kynurenine pathway (KP) is the main route of ... encoding indoleamine 2,3-dioxygenase, kynureninase or 3-hydroxyanthranilic acid oxygenase and decreases in the levels of transcripts encoding tryptophan 2,3-dioxygenase, kyn...

Ngày tải lên: 11/08/2014, 06:23

... mass. One possibility lies in the well-documented ability of dietary omega 3 fatty acids to reduce inflammatory cytokines [40], since inflammatory cytokines have the ability to increase pro- tein ... cortisol concentration using ELISA. Following baseline testing, subjects were randomly assigned in a double blind manner to one of two groups: 4 g/d of Safflower Oil (SO); or 4 g/d of...

Ngày tải lên: 11/08/2014, 23:21

... (GSH)/thiol levels using N-acetyl-L-cysteine, GSH or buthionine sulphoximine (BSO), demonstrated that both the stimulatory and the inhibitory effects of CSC were regulated in part by intracellular GSH levels. Conclusion: ... proliferation. Inhibition of cell proliferation by high concentrations of CSC was associated with activation of the pro-apoptotic MAP kinases p38 and...

Ngày tải lên: 12/08/2014, 18:20

... redox cycling and consequently quinone dependent production of reactive oxygen species. In rat and mouse, a wide range of chemicals including polyaromatic hydrocarbons, azo dyes and quinones induces ... cycling com- pounds on glutathione content and activity of glutathione- related enzymes in rainbow trout liver. Comp Biochem Physiol C 2002, 133:435-442. 24. Zhang YS, Ande...

Ngày tải lên: 13/08/2014, 13:20

... acupuncture largely depends on the choice and number of acupoints. Recent clinical investigations on musculoskeletal pain, such as myofascial pain syndrome and fibromyalgesia, focus on tender points and/ or ... and may induce pain sensation in the skin [33]. In the present study, we estimated the intensity of muscle pain of the arm at full flexion. Conclusion The presen...

Ngày tải lên: 13/08/2014, 15:21