Báo cáo y học: " Genetic polymorphisms in glutathione S-transferase (GST) superfamily and risk of arsenic-induced urothelial carcinoma in residents of southwestern Taiwan" ppt

... glutathione S-transferase (GST) superfamily and risk of arsenic-induced urothelial carcinoma in residents of southwestern Taiwan. Journal of Biomedical Science 2011 18:51. Hsu et al. Journal of Biomedical ... CJ, Pu YS, Su CT, Huang YK, Chen YT, Hsueh YM: Urinary 8-hydroxydeoxyguanosine and urothelial carcinoma risk in low arsenic exposure area. Tox...

Ngày tải lên: 10/08/2014, 05:21

... common polymorphisms in DNA repair genes are continuously being identified, and these polymorphisms may play a pivotal role in sporadic carcinogenesis. A growing body of literature, including observations ... Continued advances in SNP maps and in high-throughput genotyping methods will facilitate the analysis of multiple polymorphisms within genes and the analysi...

Ngày tải lên: 31/10/2012, 14:59

... growing understanding of how genetic and environmental factors inter- act in RA pathogenesis, and suggest that heavy cigarette smok- ing and PTPN22 may be acting in a similar mechanistic pathway. Competing ... results of their study are slightly different from ours, in that they did not find a significant interaction between the presence of the PTPN22 polymorphism and sm...

Ngày tải lên: 09/08/2014, 10:23

... is induced by AGE, can contribute to the inflammatory cycle by the induction of proinflammatory cytokines, via the nuclear factor-κB pathway [21]. No studies have yet examined RAGE expression in ... basis of having peripheral joint synovitis and not axial disease, the presence of ‘inflammatory spinal pain’, when present, was insufficient as the only major European Spondlyarthropathy...

Ngày tải lên: 09/08/2014, 01:21

... TLR3 agonist, polyinosinic-polycytidylic acid (poly(I:C)), on the growth of human NB cells was evaluated by WST-1 cell proliferation assay, flow cytometry analysis, and immunoblot analysis. Blockade of TLR3 ... TLR3 signaling was achieved using TLR3 neutralizing antibody, small interference RNA, and 2-aminopurine (2-AP), an inhibitor of protein kinase R (PKR), an interferon-induced,...

Ngày tải lên: 10/08/2014, 10:20

... maintaining hepatitis B immunity in hemodialysis patients. vaccine 2002, 20:3230-35. 21. Pyone kyi K, May Oo K, Moh Htun M, Win Maw T, Khin Khin A, San San O, et al.: Clinical trial of the intradermal ... an alternative method of vaccination which could be more effective than the conventional intramuscular (IM) rout. It is effective in inducing HBs antibody production by increasing T...

Ngày tải lên: 11/08/2014, 10:23

... ‘Shp’ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem Sci 2003, 28:284-93. 24. Qu CK: Role of the SHP-2 tyrosine phosphatase in cytokine-induced signaling and ... I, Semplicini A, Pessina AC: Silencing regulator of G protein signaling-2 (RGS-2) increases angiotensin II signaling: insights into hypertension from findings in Bartter’s/Gitelman’...

Ngày tải lên: 10/08/2014, 05:21

... hereditary and environmental factors. The disease is characterized by lymphocytic infiltration and inflam- mation in the salivary and lacrimal glands, leading to oral and ocular dryness. To understand ... development of autoimmune exocrino- pathy in the NOD mouse and by reducing one of these regions considerably, Nguyen et al. in a recent issue of Arthritis Research and...

Ngày tải lên: 09/08/2014, 01:22

... recipient of a scholarship of the National Program for the Training of University Professors of the Spanish Ministry of Education. AG was supported by the Instituto de Salud Carlos III (Spain). References 1. ... to ascertain the specific participation of each of them in RA. As a group, they are the major actors in the degradation of ECM in RA cartilage and bone. In...

Ngày tải lên: 09/08/2014, 07:20

... actions of cytokines may be profoundly conditioned by the presence of other cytokines, this being particularly true in the case of IL-10 and TNFα, which are mutually regulated and have complex and ... (73.61 and 59.97, respectively). Combined IL-10 and TNFα genotype influences response to antimalarial treatment in SLE patients Finally, in order to examine the role of...

Ngày tải lên: 09/08/2014, 07:20