... compensated by the gain of enthalpy on binding, so that the scoring function of the docking program used indicated no or only weak binding. These findings suggest that the binding affinity would ... Abbreviations CA: Capsid; CAI: Capsid Asembly Inhibitor; CAT: Conformational Analysis Tools; CD: Circular Dicroism; CLSM: Confocal Laser Scanning Micros- copy; HAART: Highly Active Ant...
Ngày tải lên: 08/08/2014, 17:20
... significant if the two-tailed p- value was <0.05. Plasma pyridoxal 5'-phosphate, tHcy, urinary XA, and 4-PA levels were log-transformed to achieve normal- ity. Analysis of covariance (ANCOVA) ... a tube containing ethylenediamine- tetraacetic acid (EDTA) (Becton Dickinson, Franklin Lakes, NJ, USA) for determination of plasma pyridoxal 5'-phosphate, fast- ing tHcy level, ery...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Identification of a SmD3 epitope with a single symmetrical dimethylation of an arginine residue as a specific target of a subpopulation of anti-Sm antibodies" ppsx
... SLE. Figure 2 Assay performance characteristics of the anti-SmD3 peptide (SMP) assayAssay performance characteristics of the anti-SmD3 peptide (SMP) assay. (a) Intra-assay and interassay variability, (b) ... (b) linearity, and (c) receiver operating characteristic analysis. The intra-assay and inte- rassay variability, expressed as coefficient of variation in percentage (CV%), o...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Identification of kinectin as a novel Behçet''''s disease autoantigen" doc
... Presence of anti-kinectin and anti-PMS1 antibodies in Japanese aplastic anaemia patients. Br J Haematol 2005, 128:221-223. 39. Imai H, Nakano Y, Kiyosawa K, Tan EM: Increasing titers and changing specificities ... Immunoscreening of expression libraries using BD sera was used since this approach has been successfully employed in the characterization of many clinically relevant anti...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Identification of citrullinated α-enolase as a candidate autoantigen in rheumatoid arthritis" doc
... Sugaya M, Hanagiri T, Yasumoto K: [Tumor marker in primary lung cancer]. J UOEH 2004, 26:473-479. 38. Suzuki A, Yamada R, Chang X, Tokuhiro S, Sawada T, Suzuki M, Nagasaki M, Nakayama-Hamada M, ... Other antibodies are also present in sera from patients with RA, including antiperinuclear factor [3] and antikeratin antibody [4]. Because both antiperinuclear fac- tor and antikeratin antibo...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Identification and characterization of the carboxy-terminal region of Sip-1, a novel autoantigen in Behçet''''s disease" docx
... Margutti P, Delunardo F, Sorice M, Valesini G, Alessandri C, Capoano R, Profumo E, Siracusano A, Salvati B, Riganò R, Ortona E: Screening of a HUAEC cDNA library identifies actin as a candidate ... in the design and revision of the study and performed the statistical analysis. RP participated in the design and revision of the study. AS partic- ipated in the analysis and inter...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Identification of a human peripheral blood monocyte subset that differentiates into osteoclasts" doc
... necrosis factor receptor-associated factor 6 5'-AGA CAA GAC CAT CAA ATC CGG GAG 3'-TCC AGG GCT ATG AAT CAC AAC AGG c-Fos 5'-CAG GAG ACA GAC CAA CTA GA 3'-TTC ACG GAC AGA TAA GGT ... GGA ATC CTG AAA CTC AGA 3'-TCC CGT TGC AGA CGT AGA AAC TGA Integrin αv 5'-TCC CAT CAG TGG TTT GGA GCA TCT 3'-TCC GAC AGC CAC AGA ATA ACC CAA Integrin β3 5'-TGC CTC AAC AAT ....
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach" pdf
... Tokuhiro S, Sawada T, Suzuki M, Nagasaki M, Nakayama-Hamada M, Kawaida R, Ono M, et al.: Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid ... Sugao 2-16-1, Miyamae, Kawasaki, Kanagawa 216-8512, Japan 2 Musculoskeletal Science, Yokohama City University Graduate School of Medicine, Fukuura3-9, Kanazawa, Yokohama, Ka...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Identification of possible candidate genes regulating Sjögren''''s syndrome-associated autoimmunity: a potential role for TNFSF4 in autoimmune exocrinopathy" docx
... (Qiagen Inc., Valencia, CA, USA) from a small tail snip taken between 2 and 4 weeks of age just prior to weaning. Each DNA sample was used as a template in polymerase chain reaction amplification ... generated by GraphPad InStat software (GraphPad Software, Inc., San Diego, CA, USA). A two-tailed P value of less than 0.05 was considered significant. Results Genetic profiling of...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "Identification of novel genetic susceptibility loci for Behçet''''s disease using a genome-wide association study" pps
... contributions YF performed the acquisition of data. RW performed the acquisition and analysis of data. BLC performed the analysis of pooling data. HD and GS-D provided DNA samples, made a substantial contribution ... ubiquitin asso- ciated and SH3 domain containing, A; UBASH3B: ubiquitin associated and SH3 domain containing, B. Available online http://arthritis-research.com/content/1...
Ngày tải lên: 09/08/2014, 14:20