Báo cáo y học: "Carbon monoxide affects electrical and contractile activity of rat myocardium" ppt
Báo cáo y học: "Carbon monoxide affects electrical and contractile activity of rat myocardium" ppt
... contractile activity of rat heart by decreasing the APD in workingatrial and ventricul ar myocardium, increasing the sinoa-trial node beating rate and suppressing the contractile activity of ... exogenous and endogenous CO onthe electrical and contractile activity of isolated rat myo-cardium preparation.MethodsThe investigation conformed with the Guide for theCare and Use of Labora tory ... role of CO endogen-ously produced in the myocardium by blocking itssynthesis using application of 10-5M ZnPP, inhibitor of Figure 1 Changes in configurat ion of electrical and contract ile activity...
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Báo cáo y học: "Developments in the scientific and clinical understanding of the spondyloarthritides" pptx
... longer-standingdisease, syndesmophytes are present in only about 50% of cases and only a smaller percentage of these patientsdevelop the typical clinical picture of patients with anankylosed ... ASAS20,ASAS40, and ASAS partial remission criteria, respectively) of clinical symptoms. Andrei Calin, of Bath, UK, had started thiskind of work in the early 90s with the definition of the BathAnkylosing ... 66:113-117.6. Kruithof E, Baeten D, De Rycke L, Vandooren B, Foell D, Roth J,Canete JD, Boots AM, Veys EM, De Keyser F: Synovialhistopathology of psoriatic arthritis, both oligo- and polyartic-ular,...
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Tài liệu Báo cáo Y học: Purification, characterization, immunolocalization and structural analysis of the abundant cytoplasmic b-amylase from Calystegia sepium (hedge bindweed) rhizomes ppt
... residues of the C. sepium b-amylase (Cys83,Cys96, Cys209 and Cys344) are homologous to those foundin soybean b-amylase (Cys82, Cys97, Cys208 and Cys343).On the analogy of the soybean b-amylase, ... method.Inhibition of the enzyme activity by glucose, maltose and cyclohexaamyloseFor the study of the enzyme inhibition by glucose, maltose and cyclohexaamylose b-amylase activity was measuredusing ... sepiumb-amylase is not glycosylated.Fig. 2. Lineweaver–Burk plots. (A) Lineweaver–Burk plots of the activity of C. sepium b-amylase on starch, amylose and amylopectin.The activity was assayed in...
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Báo cáo Y học: Conformational analysis by CD and NMR spectroscopy of a peptide encompassing the amphipathic domain of YopD from Yersinia potx
... spin system assignments of YopD278)300were obtained using COSY and TOCSYspectra and a NOESY spectrum was used to identifysequential backbone connectivities. A comparison of theHa and Cachemical ... spectroscopy of a peptideencompassing the amphipathic domain of YopD fromYersiniaTobias Tengel1, Ingmar Sethson1 and Matthew S. Francis21Departments of Organic Chemistry and 2Molecular Biology, ... determinants that are secretedby the Ysc (Yersinia secretion) type III apparatus [3,4]. Twoprotein classes are secreted by the Ysc apparatus; antihostYop-effector proteins and those required for their...
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Báo cáo y học: "Inhaled Corticosteroids, Corticosteroid Osteoporosis, and the Risk of Fracture in Chronic Asthma" pps
... daily dose of ICS .013Fewer years of prednisone exposure .032Greater physical activity .042More years of supplemental estrogen use .058Adapted from Toogood JH et al.4ANCOVA= analysis of ... terminated.13The daily dose of ICS should be sufficient tofacilitate daily weight-bearing (impact type) phys-ical activity. 14A regular exercise regimen suitedto the particular needs and capacity of each ... DXAexaminations at intervals of about 1 to 3 years.3It is not yet known whether the early intro-duction of long-term low-dose ICS therapy inyoung children with mild asthma may ultimatelyreduce the peak...
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Báo cáo y học: "The clinical-familial correlates and naturalistic outcome of panic-disorder-agoraphobia with and without lifetime bipolar II comorbidity" potx
... 1Institute of Behavior Sciences 'G. De Lisio', Carrara, Italy, 2Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, Psychiatry Section, University of Pisa, Italy, 3Adults ... evaluated and treated at the PsychiatricInstitute of the University of Pisa, Italy, from 1991 to1995, and followed for a period of 3 years. The major aim of the study was to describe the course and ... specifically designed to explore symp-toms, disability, help seeking and medications after theend of the study and in the last year [39]. After the regis-tration of the reasons of interruption,...
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Báo cáo y học: "Developments in the scientific and clinical understanding of autoinflammatory disorders" doc
... the hyper-IgD and periodic fever syndrome (HIDS), and the cryopyrin-associatedperiodic syndrome (CAPS) and acquired diseases of adult-hood, including urate arthropathy and Schnitzler syndrome.Despite ... onlythe past few years after their common genetic aetiology wasdiscovered.Clinical disease is accompanied by an acute-phase response and often leukocytosis and thrombocytosis and anaemia of chronic ... cellular localisation. Pyrinis thought to interact with a variety of proteins within thecytoplasm and to play a key role in the modulation of inflammation and apoptosis [11]. Many of its interactionsappear...
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Báo cáo y học: "Commentary on “Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus”, by RR Graham et al" pdf
... Gray-McGuire C, Moser KL, Gaffney PM, Kelly J, Yu H, Olson JM,Jedrey CM, Jacobs KB, Kimberly RP, Neas BR, Rich SS, BehrensTW, Harley JB: Genome scan of human systemic lupus erythe-matosus by ... pheno-type), and misclassification of clinical phenotypes. Hence,the task of identifying susceptibility genes for complex dis-orders is enormous.Investigation of genetic susceptibility loci forsystemic ... and such a region could contain 500 genes. Varia-CommentaryCommentary on “Genetic linkage and transmissiondisequilibrium of marker haplotypes at chromosome 1q41 inhuman systemic lupus erythematosus”,...
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Báo cáo y học: "Natural killer T cells and rheumatoid arthritis: friend or foe" ppt
... cells may activelycontribute to synovial inflammation by residing in a nichewhere they are usually absent. Hence, Vαi NKT cells werereported to appear within the synovium of wild-type miceas ... inflammatory arthritis, illustrating the diseaseperpetuating role of Vαi NKT cells in this model.Conversely, stimulation by repeated in vivo administration of α-GalCer resulted in a moderate increase ... inflammatory cascade with activation of complement and Fcγ receptor pathways [14]. This modelis considered to be reminiscent of the terminal effectormechanisms of RA. The development of antibody-inducedarthritis...
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Báo cáo y học: "Tumour necrosis factor blockade and the risk of osteoporosis: back to the future " ppt
... technique of metacarpal morphometry employed in these three old studiesis identical with that measured by modern day automatedradiogrammetry. Moreoever, automated radiogrammetry usinghand X-rays ... with BMD assessedby dual energy X-ray absorptiometry [13].In summary, studies like that by Marotte and colleagues [6]suggest TNF blockade may have a role in prevention of generalised osteoporosis ... efficacy. Application of such auto-mated radiogrammetry to the existing clinical trial data (suchas these hand X-rays) offers an opportunity to examine theeffects of TNF blockade on bone loss and...
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