Báo cáo y học: "Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan" potx

... W, Tomlinson IP, Carter NP: Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas. Cancer Res 2004, 64:4817-4825. 15. Nakao K, Mehta KR, Fridlyand ... diversities in CRC transcript profiles between Caucasian and Han Chinese populations. Additional file 6: The combined analysis of copy number alterations (CNAs) and gen...

Ngày tải lên: 10/08/2014, 05:21

... A., Inoue, K., Hiraoka, N., Ikeshiro, Y. , Kushiro, T., Shibuya, M. & Ebizuka, Y. (2001) Cloning and characterization of a cDNA encoding b-amyrin synthase involved in glycyrrhizin and soyasaponin ... by heterologous hybridization with cDNA of Glycyrrhiza glabra b-amyrin synthase. Expression of LcIMS1 in yeast lacking endogenous oxidosqualene cyclase activity resulted in...

Ngày tải lên: 08/03/2014, 23:20

... that cyclin-dependent kinase inhibitor p16 INK4a is induced in RA-SF by several growth-inhibited conditions, including irradiation, serum depletion and high cellular density. Surprisingly, they showed ... distribution of distinct genes, namely S100A4, NFAT5, Fbx3 and unr, all of which were upregulated in LD cells, by in situ hybridiza- tion. S100A4 mRNA was expressed both in t...

Ngày tải lên: 09/08/2014, 06:22

... properties. In this work we took advantage of the specific labeling with PLP of Lys288 in E. coli PEP carboxykinase to gain insight into conformational alterations of the protein upon ligand binding in ... characteristics of the native protein, allowing the determination of several pro- tein–ligand dissociation constants, as well as the role of Mg 2+ and Mn 2+ in substrat...

Ngày tải lên: 21/02/2014, 01:21

... Electron spinresonancestudyoftheroleofnitricoxideandcatalaseinthe activation of guanylate cyclase by sodium azide and hydro- xylamine. Modulation of enzyme responses by heme proteins and their nitrosyl ... center of chlorite dismutase, as it does in metmyoglobin [10]. In the case of myoglobin, as with many heme proteins, the ferric iron center is oxidized to an oxoferryl compl...

Ngày tải lên: 08/03/2014, 16:20

... and 4.7 pN in outer-arm dynein [106]; for cytoplasic dyneins, a value of  1 pN in bovine cytoplasmic dynein [107,108], 3–4 pN [109] and 7– 8 pN [110] in porcine cytoplasmic dynein and 8 pN in yeast ... dynein motility in vitro [53]. However, they may regulate dynein motility in vivo and recent data indicate that the non-catalytic subunits link dynein to cargos and to...

Ngày tải lên: 14/03/2014, 22:20

... Nayak 1 , Sachin Kumar 1 , Peter L Collins 2 and Siba K Samal* 1 Address: 1 Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, Maryland, USA and ... replacement of lysine (K) residue by another basic amino acid arginine (R). Phylogenetic analysis The phylogenetic relationship of APMV-4 with other members of family Paramyxoviridae...

Ngày tải lên: 20/06/2014, 01:20

... perceived tinnitus. Technical investigations include MRI of the brain and posterior fossa, pure tone and speech audiometry, Auditory Brainstem Response (ABR) and tympanometry. Assessment of tinnitus ... their tinnitus. Tinnitus matching is performed by presenting sounds to the ear in which the tinnitus is not perceived, and both tinnitus pitch and tinnitus intensity (a...

Ngày tải lên: 08/08/2014, 16:23

... controlled by proinflammatory cytokines and increased responses to TLR ligands. GM-CSF was shown to play an important role in inflammatory sig- naling in a model of LPS-induced lung injury. Pre- treatment ... TLR2 and TLR4 in neutrophils and monocytes. GM-CSF up-regulated expression of TLR2 and TLR4 in neutrophils and TLR2 in monocytes. TLR5 was down-regulated by i...

Ngày tải lên: 08/08/2014, 16:23

... Panax ginseng: a role in cancer therapy? Integr Cancer Ther. 2003, 2:13-33. 4. Shin JY, Song JY, Yun YS, Yang HO, Rhee DK, Pyo S. Immunostimulating effects of acidic polysaccharides extract of ... could induce cytokine release including TNF-α in these animals and inhibit tumor growth. However, further study is needed to determine how they are induced and the mechanisms the...

Ngày tải lên: 08/08/2014, 18:20