Báo cáo y học: "Vascular disrupting agent DMXAA enhances the antitumor effects generated by therapeutic HPV DNA vaccines" pdf
... of DMXAA with the DNA vaccine. iNOS plays a role in the immune suppression caused by DMXAA administration at the time of the first DNA vaccination In order to determine the mechanism by which DMXAA ... Peng et al.: Vascular disrupting agent DMXAA enhances the antitumor effects generated by therapeutic HPV DNA vaccines. Journal of Biomedical Scie...
Ngày tải lên: 10/08/2014, 05:21
... specific therapeutic action displayed by opioid agents on psychopathological symptoms. In the present report we compared the effects of buprenorphine and methadone on the psychopathological symptoms ... pathophysiology of psy- chotic disorders [43]. The antipsychotic effectiveness of opiate agonists [44] is supported by the fact that metha- done maintenance i s responsible f...
Ngày tải lên: 09/08/2014, 01:21
... edema and deformity of the hindpaws; however, SIA is primarily an enthesopathy characterized by the proliferation of fibroblasts and the formation of periarticular enthesophytes of cartilage ... by PCR with primer pairs spe- cific for the NeoR gene within the construct. Wild-type animals were determined by using another primer pair inside the Col9a1 gene that flanked the c...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Vascular involvement in rheumatic diseases: ‘vascular rheumatology" pps
... wall (tethering) followed by rolling of leukocytes on the endothelial layer. Tethering and rolling are mediated primarily by selectins and their ligands. These events are followed by leukocyte activation, ... [16,35]. Endothelin-1 antagonists currently used in the therapy of primary and SSc-associated secondary pulmonary hypertension may also exert angiostatic effects [16,28]. Acc...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "Vascular mechanism of axonal degeneration in peripheral nerves in hemiplegic sides after cerebral hemorrhage: An experimental study" ppsx
... injury and polyneuropathy [5-7]. The diameters and blood flow velocity of the femoral arteries are significantly reduced in the paralytic site [1]. The femoral arteries are innervated by the L 1–6 ... [32]. The physical proximity of the lesion to the cell body is a critical factor for the development of PNs injury [33]. The microscopic and ultra-structural changes indica...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"
... 0.05. The study was approved by the Ethics Committee of the University Hospital Centre. All patients included in the study signed an informed consent form. The study was not funded or supported by ... commonly complicated by hyperglycaemia caused by mediators of stress and inflammation. Severity of disease is the main risk factor for development of hyperglycaemia, but not...
Ngày tải lên: 25/10/2012, 10:02
Báo cáo y học: "Management of chest pain: exploring the views and experiences of chiropractors and medical practitioners in a focus group interview"
... chiro- practic physicians as the main faculty in the diagnosis classes. Therefore, it is commonly the case that cardiology classes are taught by chiropractic physicians with expertise in family practice, ... opportunity, yet this rep- resents the one area beyond the standard curriculum where further training can be gained and is therefore the only way in which current chiropract...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "Complications after spacer implantation in the treatment of hip joint infections"
... regarding systemic side effects after use of bone cement drug delivery systems in the past years. Van Raaij et al. reported the case of an 83 year old woman with no history of kidney dis- ease ... pins, intramedullary nails with two lag screws and Charnley prostheses, respectively [17]. The authors reported that all con- structs based upon the Charnley prostheses and the comm...
Ngày tải lên: 26/10/2012, 09:53
Báo cáo y học: "PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA1/2-associated breast cancers"
... of the therapeutic approaches to kill BRCA1 deficient cancer cells efficiently is treating these cells with DNA damaging reagents thereby introducing acute DNA damage. However, the majority ... with cytotoxic drugs by increasing the sensitivity of the tumors to these agents. Indeed, it has been shown that PARP-1 inhibitors not only significantly enhance the anti-tumor e...
Ngày tải lên: 31/10/2012, 16:57
Báo cáo y học: "Antiviral therapy of HCV in the cirrhotic and transplant candidate"
... related cytopenias. The use of these agents is costly and has not been studied rigorously in a randomized controlled format to assess their value and impact on efficacy of therapy although they are ... with the latest combination therapy. However, existing data support therapy of the patient with compensated cirrhosis. Cirrhotic patients may tolerate therapy less well, given the...
Ngày tải lên: 31/10/2012, 17:11