Báo cáo y học: " Cellular stress-induced up-regulation of FMRP promotes cell survival by modulating PI3K-Akt phosphorylation cascades" pdf

... Jeon et al.: Cellular stress-induced up-regulation of FMRP promotes cell survival by modulating PI3K-Akt phosphorylation cascades. Journal of Biomedical Science 2011 18:17. Submit your next manuscript ... 15 RESEARC H Open Access Cellular stress-induced up-regulation of FMRP promotes cell survival by modulating PI3K-Akt phosphorylation cascade...

Ngày tải lên: 10/08/2014, 05:21

... mastocytoma P-815 was readily phosphorylated by CaM kinase II. Although the TPH from P-815 cells was easily phosphorylated by this kinase, its enzymic activity was not altered by the phosphorylation ... effect of TPH phosphorylation by CaM kinase II on the susceptibility of the enzyme to degradation in our cell- free proteasome system. As shown in Fig. 4B, degradation of TP...

Ngày tải lên: 08/03/2014, 16:20

... pathology has yet to be fully examined. A role for the proinflammatory cytokines TNFα and IL-1β in innervation of the IVD [22] and in degeneration of the IVD has been demonstrated by a number of authors ... the high-affinity receptors by cells of the non-degenerate and degenerate IVD, however, implicates an autocrine role for neu- rotrophins in disc cell metabolism. Enhancement...

Ngày tải lên: 09/08/2014, 11:20

... dsCYCs. ds, diatom specific. CYCB2 CYCA/B;1 CYCB1 CYCD1 CYCH1 CYCP2 CYCP6 CYCP3 CYCP4 CYCP5 CYCL1 CYCP1 CYC-like dsCYC3 dsCYC4 dsCYC2 dsCYC10 dsCYC6 dsCYC8 dsCYC1 dsCYC9 dsCYC5 dsCYC7 dsCYC11 (b) (a) 0h 1h 6h 5h 4h 3h 2h 8h 9h 7h 10h 11h 12h 0h 1h 6h 5h 4h 3h 2h 8h 9h 7h 10h 11h 12h -3.0 ... Oelgeschläger T: Regulation of RNA polymerase II activity by CTD phosphorylation and cell cyc...

Ngày tải lên: 09/08/2014, 20:21

... signifi- cance, range of assembly software, and (most critically) the availability of low level assembly data including the place- ments of reads in contigs. We chose to analyze the UMD2 cow assembly over the ... correction of false segmental duplications caused by genome mis-assembly Genome Biology 2010, 11:R28 Kelley and Salzberg Genome Biology 2010, 11:R28 http://genomebiology....

Ngày tải lên: 09/08/2014, 20:21

... profiling of the yeast genome. Mol Cell 2004, 16:487-496. 14. Nurse P: A long twentieth century of the cell cycle and beyond. Cell 2000, 100:71-78. 15. Yanagida M: Basic mechanism of eukaryotic chromosome ... localized by a genome-wide localization study [49]. The individual Bioneer deletion strains of these two genes were verified by PCR analysis and their TBZ sensitivity...

Ngày tải lên: 09/08/2014, 20:22

... viral entry by macrophage tropic R5 and T -cell tropic-X4 HIV respectively [16,17]. The primary HIV infection is estab- lished by R5 virus and during the later stages of disease, T- cell tropic ... (R). Primary PCR was done with 10 cycles of 95°C for 5 sec and 70°C (-0.5°C per cycle) for 2 min fol- lowed by 20 cycles of 95°C for 5 sec and 65°C for 2 min. Nested PCR was done by...

Ngày tải lên: 10/08/2014, 05:21

... imple- mentation program included all of these dimensions. The stan dard of care is not the same as the quality of care. The quality of care provided by the clinician may be below, equal to, or even ... Depression seriously reduces the quality of life for individuals and their families, and often aggravates the outcome of other physical health problems. Because depression is hig...

Ngày tải lên: 11/08/2014, 05:21

... recycling of eIF2 to this form [29,30]. The activity of eIF2B can be modulated in a variety of ways [29,31] including by its own phosphoryla- tion, and through phosphorylation of the a subunit of ... Proud 1,2 1 Department of Biosciences, University of Kent at Canterbury, Canterbury, UK; 2 Division of Molecular Physiology, School of Life Sciences, University of Dundee,...

Ngày tải lên: 18/03/2014, 01:20

... purposes) Annals of General Psychiatry Open Access Primary research Cellular mechanisms underlying the effects of an early experience on cognitive abilities and affective states Efstathios Garoflos † , Theofanis ... (RIA). Data were statistically analyzed by analysis of variance (ANOVA). Results: Neonatal handling increased the ability of male rats for spatial learning and memory...

Ngày tải lên: 08/08/2014, 21:20