Báo cáo y học: " The functional expression of extracellular calcium-sensing receptor in rat pulmonary artery smooth muscle cells" potx

Báo cáo y học: " The functional expression of extracellular calcium-sensing receptor in rat pulmonary artery smooth muscle cells" potx

Báo cáo y học: " The functional expression of extracellular calcium-sensing receptor in rat pulmonary artery smooth muscle cells" potx

... sensing receptor (CaSR) is ex pressed in pulmonary artery smooth muscle cells (PASMCs ) and homogenates of pulmonary arteries (PAs). A. Detection of CaSR mRNA by RT-PCR in rat PASMCs in the absence ... CQ: Involvement of calcium-sensing receptor in cardiac hypertrophy-induced by angiotensin II through calcineurin pathway in cultured neonatal rat cardiomyo...
Ngày tải lên : 10/08/2014, 05:21
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Báo cáo y học: "The functional spectrum of low-frequency coding variation" pot

Báo cáo y học: "The functional spectrum of low-frequency coding variation" pot

... as explained in the SNP calling methods. Base quality recalibration The base qualities reported by the instrument were recalibrated using GATK as explained in the SNP calling methods. INDEL calling INDELs ... 1, in order to remove the high number of false posi- tive INDELs in this category. Broad Institute Illumina INDEL calling pipeline Read mapping The BI Illumina INDE...
Ngày tải lên : 09/08/2014, 23:20
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Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"

Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"

... quality improvement as a distinct career pathway. Involving such physicians in medical emergency teams will likely facilitate the dual roles of these as a clinical outreach arm of the intensive ... substantial investments of time and money. Moreover, especially in the case of chart review, missing information often limits the ability of reviewers to identify adverse even...
Ngày tải lên : 25/10/2012, 10:06
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Báo cáo y học: "The opposite effects of fluvoxamine and sertraline in the treatment of psychotic major depression: a case report" potx

Báo cáo y học: "The opposite effects of fluvoxamine and sertraline in the treatment of psychotic major depression: a case report" potx

... to antipsychotics. In this case, fluvoxamine monotherapy was effective in the treatment of psychotic major depres- sion, and the switch to sertraline worsened the psychotic symptoms in the patient. The ... psychopharma- cology from that of other SSRIs [29]. It is therefore possible that activation of the dopaminergic system by the inhibition of dopamine transporter...
Ngày tải lên : 08/08/2014, 23:21
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Báo cáo y học: " The contrasting roles of PPARδ and PPARg in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue" ppt

Báo cáo y học: " The contrasting roles of PPARδ and PPARg in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue" ppt

... the integration of the energy metabolism pathways of 3T3-L1 adipocytes. A diagram showing the effect of PPARg activation on the integration of the energy metabolism pathways of 3T3-L1 adipocytes based ... observed by the increase in the creatine concentration within 3T3-L1 adipocytes treated with the PPARδ agonist, demonstrating an alteration to the high energy p...
Ngày tải lên : 09/08/2014, 23:20
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Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot

Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot

... replaced by the STAT1 recruiting motif of the interferon-c receptor result- ing in a chimeric protein designated gp130c.Inorderto investigate the role of the membrane-proximal domains of gp130 in receptor ... epitopes of both receptors. Deletion of a single domain in the membrane-proximal part of gp130 leads to a shift of the receptor areas involved in...
Ngày tải lên : 18/03/2014, 01:20
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Báo cáo sinh học: "The functional landscape of mouse gene expression" pdf

Báo cáo sinh học: "The functional landscape of mouse gene expression" pdf

... were inferior (dotted magenta line in Figure 6a). In theory, if any combination of on/off information about gene expression in different tissues was informative for identifying genes in any cate- gory, ... discriminant values above the given dis- criminant value really are in the category in question. The proportion of known genes in the category that are identi- f...
Ngày tải lên : 06/08/2014, 18:21
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Báo cáo y học: "The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanase" docx

Báo cáo y học: "The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanase" docx

... of the drug on the regulation of 5-LOX, one of the main enzymes involved in the synthesis of LTB 4 by chondrocytes [4,24]. Figure 2 Cathepsin K gene expression and protein synthesisCathepsin ... simultaneously reducing the synthesis of LTB 4 and IL-1β by the OA synovium [6]. These findings are in strong support of the in situ role played by LTB 4 in the...
Ngày tải lên : 09/08/2014, 06:23
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Báo cáo y học: "tatin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis" pptx

Báo cáo y học: "tatin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis" pptx

... immunomod- ulatory potential in RA [24]. Recognizing the preliminary nature of the clinical data supporting a disease-modifying effect for statins in RA and the need for in vivo confirmation of our find- ings, ... decay-accelerating factor expressionHypoxia increases atorvastatin-induced decay-accelerating factor expression. Analysis of decay-accelerating factor expression...
Ngày tải lên : 09/08/2014, 08:22
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Báo cáo y học: "Differential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patients" pptx

Báo cáo y học: "Differential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patients" pptx

... aligned in a disorganised manner, which may contribute to the under-mineralisation in OA [8]. Interestingly, the findings of the present study indi- cated that the ratio of COL1A1/COL1A2 mRNA expression was ... subsequently accumulated in the mineralised matrix. Increased OPN may augment OB synthetic activity by increasing OB longevity and surface extent of bone format...
Ngày tải lên : 09/08/2014, 08:23
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