Báo cáo y học: " Regulation of cardiac microRNAs by serum response factor" potx
Báo cáo y học: " Regulation of cardiac microRNAs by serum response factor" potx
... expression of a number of microRNAs. Interestingly, downregulation
of miR-1, miR-133a and upregulation of miR-21 occurred by 7 days of age in these mice, long before the onset of
cardiac hypertrophy, ... 18:15
http://www.jbiomedsci.com/content/18/1/15
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RESEARCH Open Access
Regulation of cardiac microRNAs by serum
response factor
Xiaomin Zhang, Goha...
Báo cáo y học: " Regulation of Sox9 activity by crosstalk with nuclear factor-κB and retinoic acid receptors" pptx
... were analyzed by densitometry using Kodak
Digital Science software (Eastman Kodak, Rochester, NY,
USA). Data were analyzed by paired t-tests, or by analysis of
variance followed by Tukey's multiple ... command of p300, because Sox9 activity was
reduced by approximately 50% when NF-κB was activated.
However, the demand for p300 is controlled not only by rela-
tive affinity...
Báo cáo khoa học: Regulation of arginase II by interferon regulatory factor 3 and the involvement of polyamines in the antiviral response potx
... ArgII and ⁄ or polyamine in the regulation of apop-
tosis [21,22]. Thus, the possibility that the antiviral
effect of spermine is mediated by induction of apop-
tosis was analyzed. For this purpose, ... inhibited by pyrrolidine dithio-
carbamate [28]. In Raw 264.7 cells cocultured with
H. pylori, ArgII expression was inhibited by MG-132
[20], suggesting indirectly an involvement...
Tài liệu Báo cáo Y học: Regulation of transcription of the Dnmt1 gene by Sp1 and Sp3 zinc finger proteins doc
... identification by Bigey et al.ofmany
Correspondence to K. K. Yokoyama, Gene Engineering Division,
Department of Biological Systems, BioResource Center, Tsukuba
Institute, RIKEN (The Institute of Physical ... exclusively but, rather, by a set of different
proteins that are structurally related [1]. The promoter
regions of many eukaryotic genes contain GC-rich sequences
[2] and some...
Báo cáo Y học: Regulation of a1,3galactosyltransferase expression in pig endothelial cells Implications for xenotransplantation doc
... the
Prime-a-gene labeling system (Promega). Double-positive
clones were purified by secondary and tertiary r ounds of
screening and genomic DNA inserts were purified using
poly(ethylene glycol) precipitation ... responsible for the hyperacute
vascular rejection occurring in pig-to-primates organ trans-
plantation. The synthesis of the aGal epitope is catalyzed by
the enzyme a1,3-galacto...
Báo cáo Y học: Regulation of RAS in human platelets Evidence that activation of RAS is not sufficient to lead to ERK1-2 phosphorylation pot
... study
down -regulation of the RAS–ERK signalling p athway and
other functions of RAS. Down -regulation of the RAS–
ERK pathway may be a critical step in the process of end-
stage megakaryocyte ... the a bility of TPO to
activate the e arly events of the R AS signalling pathway.
However, a recent study reported that inhibitors of
PtdIns3K abolished potentiation of ERK by TP...
Báo cáo Y học: Regulation of stress-activated protein kinase signaling pathways by protein phosphatases pot
... phosphatases in the
regulation of yeast SAPK pathways, then fo cus on the
properties of the protein phosphatases implicated in
the mammalian SAPK systems.
REGULATION OF SAPK SIGNAL
PATHWAYS BY PROTEIN
PHOSPHATASES ... pharmacological inhibition of protein phospha-
tase 1 by 1 ,2-dioleoyl- sn-glycero-3-phosphate (PA); the
activation of PP2A by high doses of PA, however, d...
Báo cáo Y học: Regulation of glypican-1, syndecan-1 and syndecan-4 mRNAs expression by follicle-stimulating hormone, cAMP increase and calcium influx during rat Sertoli cell development pptx
... glycosylphophatidylinositol (GPI)
anchors [1,2]. Although the primary structure of the glypi-
cans is only marginally conserved (about 30% identity), there
is a strict conservation of 14 cysteine ... amplified by relative quantitative RT-PCR
as described previously [24]. Glyp-1, glypican-1; synd-1, syndecan-1;
synd-4, syndecan-4. (A) Agarose gel of one representative experiment.
(B) De...
Báo cáo Y học: Regulation of peptide-chain elongation in mammalian cells pptx
... ADP-ribosylated by diphtheria toxin
[25]. ADP-ribosylation inhibits the activity of eEF2.
Phosphorylation of eEF2 inhibits its activity, in translo-
cation and in poly(U)-directed polyphenylalanine synthesis
[26,27], ... phosphorylation by MS6K
may be involved in their regulation in response to serum
in vivo.
eEF1A and eEF1B are also substrates for phosphoryla-
tion by the cla...
Báo cáo Y học: Regulation of mammalian translation factors by nutrients pot
... Thr70, the sites most profoundly
affected by rapamycin, may be regulated by nutrients
through the mTOR pathway.
REGULATION OF 4E-BP1 BY AMINO
ACIDS
In a number of kinds of mammalian cells, amino ... primarily by 1-leucine in isolated adipocytes. Am. J.
Physiol. 44, C1232–C1238.
109. Lynch, C.J. (2001) Role of leucine in the regulation of mTOR by
amino acids: revelation...