Báo cáo y học: "System in biology leading to cell pathology: stable proteinprotein interactions after covalent modifications by small molecules or in transgenic cells" pot
Báo cáo y học: "System in biology leading to cell pathology: stable proteinprotein interactions after covalent modifications by small molecules or in transgenic cells" pot
... H Open Access System in biology leading to cell pathology: stable protein-protein interactions after covalent modifications by small molecules or in transgenic cells Halina Z Malina Abstract Background: ... this article as: Malina: System in biology leading to cell pathology: stable protein-protein interactions after covalent modification...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Therapeutic effects of antibodies to tumor necrosis factor-α, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis" docx
... suggesting that IL-6 is also pathologically crucial in the early effector phase in arthritis. Role of various inflammatory cytokines in GPI-induced arthritis To determine the effects of inflammatory ... these cytokines could play a crucial role in the induction of arthritis in GPI-induced mice. Anti-cytokine mAbs and co-stimulator blockade inhibit in vitro cytokine production...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: " Dapsone-induced agranulocytosis leading to perianal abscess and death: a case report" pdf
... were performed during Dap- sone therapy because of the normal hemoglobin level. In order to monitor anemia, leukocytopenia, and methemo- globinemia, blood tests are required every week for the first ... agranulocytosis than normal [1]. Careful observation is required when treating with Dap- sone for an inflammatory disease such as LABD. Her hemoglobin prior to initiation of Dapsone ther...
Ngày tải lên: 11/08/2014, 00:23
Báo cáo y học: " Congenital hepatic fibrosis leading to cirrhosis and hepatocellular carcinoma: a case repor" pptx
... It occurs in association wi th a range of inherited disorders involving the kidneys. Although infantile-type polycystic kidney disease is usually an autosomal recessive disor- der, our patient in the ... followed regularly without any com- plications such as abdominal pain, jaundice, hematem- esis, tarry stool, or increases in liver enzymes. No history could be elicited of alcohol abu...
Ngày tải lên: 11/08/2014, 00:23
Báo cáo y học: "Impact of the Kenya post-election crisis on clinic attendance and medication adherence for HIV-infected children in western Kenya"
... the Indiana University School of Medicine (Indianapolis, Indiana). Informed consent was obtained for key informant inter- views, and all clinical investigation was conducted accord- ing to the ... sampling to iden- tify key informants, including physicians, nurses, and clinical officers, based on their locations and roles during the conflict. A trained facilitator conducted 9 interviews u...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: "Serum cystatin C levels to predict serum concentration of digoxin in Japanese patients
... to the cystatin superfamily of cysteine protease inhibitors [1, 2]. Cys-C is produced by all nucleated cells and is secreted into the blood at a constant rate [1, 2]. Cys-C is freely filtered ... words: Cystatin C, Creatinine, Digoxin, Serum concentration, Heart failure, Renal clearance 1. Introduction Cystatin C (Cys-C) is a non-glycosylated cationic protein of 13.3 kDa, belonging...
Ngày tải lên: 31/10/2012, 17:08
Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
... played by cytokines in the evolution of insulin resistance. Could hyperhomocysateineamia be a result of derangement of certain cytokine production? Abbreviations tHcy: total homocysteine; ... subjects gave informed consent before the study began. Patients who had history of myocardial infarction (confirmed by ECG findings and elevated troponin T) were included in the study. All p...
Ngày tải lên: 03/11/2012, 09:49
Tài liệu Báo cáo Y học: Uncoupling of protein-3 induces an uncontrolled uncoupling of mitochondria after expression in muscle derived L6 cells ppt
... oligomycin of L6 cells showed that they were very well coupled. The oligomycin resistant respiratory activity of the cells could be strongly stimulated by the addition of the protonophore carbonyl ... on mitochondrial DY in skinned cells. Recording of the m itochondrial membrane potential DY was performed with t he flu orescent p robe 3,3 ¢-dihexyloxacarbocyanine DiOC6. L6 cells expressing...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo Y học: The refolding of type II shikimate kinase from Erwinia chrysanthemi after denaturation in urea pot
... for folding of chymotrypsin inhibitor 2 ana- lysed by protein engineering methods: evidence for a nucleation- condensation mechanism for protein folding. J. Mol. Biol. 254, 260–288. 9. Radford, ... l M . RESULTS Unfolding of enzyme Stability of the enzyme. The loss of secondary and tertiary structure during unfolding of SK by urea were monitored by changes in far UV CD and fluorescence...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: The role of the second binding loop of the cysteine protease inhibitor, cystatin A (stefin A), in stabilizing complexes with target proteases is exerted predominantly by Leu73 pdf
... His75, in the second binding loop of the family 1 inhibitor, cystatin B, for high-affinity binding to a number of cysteine proteases [37]. The sequence of the corresponding hairpin loop in cystatin ... being largest, 45% of the total binding energy, for inhibition of cathepsin B. Keywords: cathepsins; cystatin; cysteine proteases; papain; second binding loop. Cystatins are effective pr...
Ngày tải lên: 17/03/2014, 10:20