Báo cáo y học: "Structural and functional characterization of human apolipoprotein E 72-166 peptides in both aqueous and lipid environments" pot

... apoE- (72-166) peptides in PBS and also in the presence of DHPC, SE experiments we re performed. The SE and SV data were combined and globally fitted to a multiple discrete species model using SEDPHAT. ... positive ly correlates with the increasing concentration of DHPC. Protein -lipid interactions and Protein-LDLR binding of ApoE- (72-166) Proteins To identify and com...

Ngày tải lên: 10/08/2014, 05:21

... represented by the red line while genes with short 5’UTR introns are represented by the blue line. The vertical line represents the top 5% of mean expression level of all genes. (d) Total 5’UTR intron ... divided by the presence of 5’UTR introns and by the number of tissues in which expression was detected. The number of tissues in which expression was detected was independent...

Ngày tải lên: 09/08/2014, 20:21

... occurred during the – presumed open label – period of follow up. They did not attempt to calculate incidence rates (e. g. per 1000 person-years of exposure), given the difficulty in ascertaining the ... cancers (9/35), and a further four were identified within 6 weeks of starting therapy. Even excluding these cases, the increased risk compared with the comparison arms was still pres...

Ngày tải lên: 09/08/2014, 08:22

... deletion, because it is more likely to recombine and less likely to have a severe phenotype when one redun- dant gene is deleted. Fewer tandem duplicate genes in the Br genome may, therefore, be attributable ... to pericentromeric heterochromatin gaps. The genome coverage of the gene-rich Br sequences was esti- mated by representation in two different datasets: expressed sequence tag...

Ngày tải lên: 09/08/2014, 20:20

... non- photic zeitgebers, including the imposed sleep-wake cycle, social cues, and activity/rest. There is evidence that the sleep-wake cycle is a potent zeitgeber; this effect may be independent of the light-dark ... volunteers in the present study were asked to maintain their usual sleep-wake and daily routines. These routines were often quite erratic, which might have rendered the ci...

Ngày tải lên: 10/08/2014, 09:20

... manually recording the same time data in the ambulance records. We registered the frequencies of completion of these patient encounter times, both in the electronic EMCC records and in the ambulance ... [23,24]. In our study, only one-half of patient encounter times were electronically transmitted back to the EMCC by the EMS services, yet these time points were documented i...

Ngày tải lên: 25/10/2012, 09:56

... all Met bonds in the TC sequence were cleaved completely, we obtained also a number of joined peptides, for instance, peptides 4–5 and 10–11, which comprised the sequences between Met residues ... quarter of the full-length sequence. Antigenic properties of the synthetic peptides Two synthetic peptides of 30 residues P A and P B were produced (see Experimental procedures)...

Ngày tải lên: 20/02/2014, 01:20

... light-emitting oxidation of luciferin by luciferase in the presence of extremely low levels of ATP. After collecting the chondrocytes by scraping, cells were centri- fuged for 10 min at 500 × g in ... series of ethanol solutions and infiltrated with xylene and before being embedded in paraffin and cut into 6-µm sections. Sections were deparaffinized through sequential imme...

Ngày tải lên: 09/08/2014, 06:23

... differences in patients’ preference of footwear style and type. The current study used a self- reported questionnaire to identify footwear style based upon postural stability and falls prevention. ... reflecte d in the current study in the higher use of sandals. Despite the benefits of therapeutic footwear that have been previously reported [9,28-31], this type of footwear w...

Ngày tải lên: 10/08/2014, 21:24

... membranes. Both isoforms are involved in the water–water cycle, a system to scavenge reactive oxygen species in chloro- plasts and dissipate excess excitation energy of photo- systems [2]. The ... broken line. Fe, nitrogen, oxygen and the cation near Trp265 are shown in cyan, blue, red and magenta, respectively. Residue numbers refer to stro- mal APX of spinach; see Fig. 1....

Ngày tải lên: 16/03/2014, 14:20