Báo cáo y học: " Conserved charged amino acid residues in the extracellular region of sodium/iodide symporter are critical for iodide transport activity" potx

... 5 of 9 RESEARC H Open Access Conserved charged amino acid residues in the extracellular region of sodium /iodide symporter are critical for iodide transport activity Chia-Cheng Li 1† , Tin-Yun ... extracellular region of NIS has been demonstrated to be critical for iodide transport in our previous study. The conserved charged amino...

Ngày tải lên: 10/08/2014, 05:21

... cis-ele- ments may partly depend on the nature of the interacting bHLH partner, taking in account the fact that the interaction can modify the structural conforma- tion of the MYB DNA-Binding domain [9,27-29]. MYB ... cells and compared to those of the native protein. VvMYB5b R and VvMYB5b L capabilities to physically interact with the bHLH protein VvMYC1 were assessed...

Ngày tải lên: 11/08/2014, 11:21

... Nevertheless, they were aspartic-rich in EDTA-SM whilst being quite glutamic acid- rich in WSM. Glycosaminoglycan analysis Glycosaminoglycans are highly negatively charged because of the presence of sulfate ... revealed the predominance of two amino acids: alanine (39.2%) and glycine (30%). Interestingly, the proportions are very similar to those found in WSM for...

Ngày tải lên: 21/02/2014, 01:21

... could not induce the repair of osteochondral defect. Interestingly, remarkably strong staining for hyaluronan was demonstrated in areas that were simultaneously devoid of staining for keratan ... follows: day 1, 10 minutes at 10 m/min; day 2, 15 minutes at 12 m/min; day 3, 20 minutes at 15 m/min; day 4, 30 minutes at 18 m/min; and day 5, 35 minutes at 20 m/min. On day 8 and therea...

Ngày tải lên: 09/08/2014, 10:22

... BIRADS). The radiological appearance was highly suggestive of a lymphoma. Then she underwent targeted fine-needle aspiration cytology (FNAC) of the axillary lesion and core needle biopsy of the breast ... 5:348 http://www.jmedicalcasereports.com/content/5/1/348 Page 4 of 4 CAS E REP O R T Open Access Toxoplasmosis presenting as a swelling in the axillary tail of the brea...

Ngày tải lên: 10/08/2014, 23:22

... Measurements of the selectivity of aminoacyl-tRNA synthetases in vitro indicate that the upper limit for error in the selection of correct amino acid for protein synthesis is in the range of 10 )4 )10 )5 . ... positioning of the acceptor stem in the active site of the enzyme. Either these docking interactions or the interaction with the acceptor s...

Ngày tải lên: 31/03/2014, 08:20

... alternate interpretation of the lack of agonist-induced BRET observed in this study is that the translation of agonist binding to the ATDs of the family C GPCR homodimer into G-protein coupling of the ... 2002 Agonist-induced rearrangement of the 7TMs in the CaR homodimer? One of the goals of the present study was to investigate, whether the activating...

Ngày tải lên: 08/03/2014, 09:20

... intervening loop. Acidic residues that may potentially compensate for the loss of the negative charge are located nearby in the two Mycoplasma sequences but are positioned in the region corresponding ... which the sequences forming the pin region differ significantly from this pattern (Fig. 1B). These RuvA p roteins have a n additional four amino acids and l ack...

Ngày tải lên: 17/03/2014, 17:20

... within the inflammatory infiltrates in the joints of the CCR2 –/– mice [19]. Data from the knockout mice suggest that at least some individual inflammatory chemokine receptors are pivotal in the ... shown to inhibit 90% of the monocyte chemotactic activity present in the synovial fluid of the majority of RA patients [30]. In a randomized study patients with a...

Ngày tải lên: 09/08/2014, 01:23

... processes underlying RP and PAH contribute to the familiar pattern of skin, renal and gastrointestinal pathology. The emergence of effective and conveniently administered therapy for PAH increases the importance ... vasculopathy of SScl may also be modifiable. In the characteristic microangiopathy of SScl, luminal narrowing results from a combination of intimal prolifera...

Ngày tải lên: 09/08/2014, 06:23