Báo cáo y học: "Association of phospholipase A2 receptor 1 polymorphisms with idiopathic membranous nephropathy in Chinese patients in Taiwan" pptx
... Access Association of phospholipase A2 receptor 1 polymorphisms with idiopathic membranous nephropathy in Chinese patients in Taiwan Yu-Huei Liu 1, 2 , Cheng-Hsu Chen 3 , Shih-Yin Chen 1, 2 , Ying-Ju Lin 1, 2 , ... H1 carriers (H1/H1), 11 8 heterozygous haplotype H1 carriers (H1/nonH1), and 69 individuals lacking haplo type H1 (nonH1/nonH1). Patients with d...
Ngày tải lên: 10/08/2014, 05:21
... of LY 315 920/S-5920, [[3-(aminooxoacetyl)-2-ethyl -1- (phenyl- methyl)-1H-indol-4-yl]oxy] acetate, a potent and selective secretory phospholipase A2 inhibitor: A new class of anti- inflammatory drugs, SPI. ... Synovitis: 0 = normal; 1 = mild synovial hypertrophy (<5 cell layers) with few inflammatory cells; 2 = moderate synovial hypertrophy (<20 cell layers) with accumula...
Ngày tải lên: 09/08/2014, 01:23
... CNX-pcDNA3 .1/ Hygro or CRT-pcDNA3 .1/ Hygro or pcDNA3 .1/ Hygro alone using lipofectAMINE PLUS reagent. Cells were then cultured in Ham’s F -12 medium in the case of CHO cell lines and RPMI medium in that of ... m M sodium butyrate, the cells (2 · 10 6 ) were preincubated for 2 h in Met- and Cys-free DMEM supplemented with 10 % dialyzed fetal bovine serum, 10 m M sodium but...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo y học: "Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients" potx
... onset of patients carrying a PTPN22 18 58T allele was 5.5 years younger com- pared to patients without such a genotype (CT and TT geno- type 45.5 years versus CC genotype 51. 0 years; p = 0.029), in ... geno- type was present in 37.9% of patients and 19 .2% of healthy controls, resulting in an OR of 2.57 (95% CI 1. 85–3.58, p < 0.0 01) . Carriage of a homozygous TT...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Association of FCGR2A and FCGR2A-FCGR3A haplotypes with susceptibility to giant cell arteritis" pdf
... 0.208 13 1H -15 8V 0.259 0. 212 FCGR3A-FCGR3B 15 8F-NA2 0.347 0.444 15 8F-NA1 0.272 0.268 0 .16 15 8V-NA2 0.339 0.225 15 8V-NA1 0.042 0.063 FCGR3B-FCGR2B NA2 -12 06G 0.426 0.343 NA2 -12 06A 0.255 0. 317 0.30 NA1 -12 06G ... (FcγRIIa -13 1R and FcγRIIIa -15 8F). FcγRIIa is the major phagocytic FcγR in humans and has two co-dominantly expressed alleles, 13 1H and 13 1R. The 13 1H iso...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Association of reduced heme oxygenase-1 with excessive Toll-like receptor 4 expression in peripheral blood mononuclear cells in Behçet''''s disease" potx
... regulatory systems in inflammatory diseases of humans, including BD. We are interested in heme oxygenase (HO) -1, because accumulating evidence suggests that HO -1 protects the host in a variety of pathologic ... oxygenase -1 deficiency. J Clin Invest 19 99, 10 3 :12 9 -13 5. 24. Kirino Y, Takeno M, Iwasaki M, Ueda A, Ohno S, Shirai A, Kanamori H, Tanaka K, Ishigatsubo Y: Incr...
Ngày tải lên: 09/08/2014, 10:22
Báo cáo Y học: Expression of the uncoupling protein 1 from the aP2 gene promoter stimulates mitochondrial biogenesis in unilocular adipocytes in vivo potx
... biogenesis by ectopic UCP1 in HeLa cells was shown to involve up-regulation of NRF -1 [42]. In our experiments, an increase of NRF -1 mRNA level was detected in 3T3-L1 adipocytes incubated with 2,4-dinitrophenol ... uncoupling protein 1 (UCP1) is a speci®c marker of multilocular brown adipocytes. Ectopic UCP1 in white fat of aP2-Ucp1 mice mitigates development of obesi...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo y học: "Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation" ppt
... by increase in proinflammatory cytokines, a key factor for the development of insulin resistance. SR1 417 16A, a cannabinoid receptor 1 (CB1) antagonist, shows significant improvement in clinical ... available soon. Effect of the Cannabinoid Receptor- 1 antagonist SR1 417 16A on human adipocyte inflammatory profile and differentiation Journal of Inflammation 2 011 , 8:33 d...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"
... ns Apo B (mg/dl) 10 0±22.6 10 3.3± 21. 1 10 3 11 .1 111 .5±9.8 ns Apo A1 (mg/dl) 15 9±26.8 16 1±24.3 16 1 .1 13 .3 15 9±22 .1 ns Lp(a) (mg/dl) 6±4.2 12 14 .1 12 .1 8.8 10 .7±3.4 ns *referring to TT vs CT/TT; ... ns LDL 18 3±46.8 18 9±54.8 19 4±53.9 17 4.6±62.5 ns HDL 65.5±20.6 53.5 16 54 16 58.2 17 .8 0.004 VLDL 22 13 .2 23±8.8 23.4±8.8 19 .2±4.8 ns Triglycerides (m...
Ngày tải lên: 31/10/2012, 17:03
Báo cáo Y học: Association of human tumor necrosis factor-related apoptosis inducing ligand with membrane upon acidification pdf
... 1- anilinonaphthalene-8-sulfonate in solution. Biochemistry 18 , 12 92 12 96. 29. Stryer, L. (19 65) The interaction of a naphthalene dye with apo- myoglobin and apohemoglobin. A fluorescent probe of non-polar binding sites. ... previously [27]. Liposome binding assay The amount of liposome-bound TRAIL was determined as follows: TRAIL at 10 lgÆmL )1 was incubated at 25 °Cfor 30...
Ngày tải lên: 31/03/2014, 08:20