Báo cáo y học: " High cell density and latent membrane protein 1 expression induce cleavage of the mixed lineage leukemia gene at 11q23 in nasopharyngeal carcinoma cell line" ppt
Tài liệu Báo cáo khoa học: High-affinity ligand binding by wild-type/mutant heteromeric complexes of the mannose pptx
... localeffect because binding of PMP-BSA, which binds toother sites in the ectodomain of these heterodimers,resulted in the predicted amount of ligand binding. This loss of binding function observed ... dimerpartners all along the ectodomain of the receptor.Collectively, these studies led to the hypothesis thatproduction of high-affinity ligand binding arises fromcooperation between Man-6-P binding sites ... IGF-II to the wild-type side, butnot to the mutant side of the dimer. Overall, the analysis of IGF-II binding in such receptor dimerssuggests that each half of the dimer is capable of binding...
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Báo cáo hóa học: " Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinom" pot
... cited.Research Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinomaJing Chen 1, 2,3, Chun-Fang ... overexpression of LMP1 upregulated the mTOR signaling pathway, possibly through phosphorylation of AKT /mTOR/ P70S6K/4EBP1 in the NPC cell lines HONE1 and 6 -10 B. Knockdown of LMP1 reduced expression of p -mTOR ... < 0.0 01 n = 219 p-P70S6K expressionLow 57 58 11 5High 22 81 103 0.293 < 0.0 01 n = 218 p-4EBP1 expressionLow494493High 31 96 12 7 0.290 < 0.0 01 n = 220 Chen et al. Journal of Translational...
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Báo cáo y học: "T-cell senescence and contraction of T-cell repertoire diversity – catalysts of autoimmunity and chronic inflammation" pdf
... one or very few differentTCR α-chains [3,4].ReviewAgeing, autoimmunity and arthritis T-cell senescence and contraction of T-cell repertoire diversity – catalysts of autoimmunity and chronic ... 5 Goronzy and WeyandIt is generally assumed that this high degree of TCR diver-sity is necessary to guarantee recognition of the universe of antigenic peptides. In fact, the T-cell repertoire ... Kopecky SL, Frye RL,Goronzy JJ, Weyand CM: T-cell- mediated lysis of endothelialcells in acute coronary syndromes. Circulation 2002, 105:570-575.84. Nakajima T, Goek O, Zhang X, Kopecky SL, Frye...
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Báo cáo y học: "High resolution discovery and confirmation of copy number variants in 90 Yoruba Nigerians" pdf
... examined known copy number variants in 10 Yoruba using Agilent microarrays; and in the Wang et al. [15]study, 36 Yoruba were genotyped using Illumina BeadChips.For each Yoruba individual in common ... CNVs, and type large numbers of individuals in order to gain biological insights beyond the initial discovery. Materials and methodsArray synthesisArrays were synthesized following standard Affymetrix ... R125ResearchHigh resolution discovery and confirmation of copy number variants in 90 Yoruba NigeriansHajime Matsuzaki, Pei-Hua Wang, Jing Hu, Rich Rava and Glenn K FuAddress: Affymetrix, Inc., 3420...
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Báo cáo y học: " High recombination rates and hotspots in a Plasmodium falciparum genetic cross" docx
... analysis, and writing; NL, VG, SV, VN, MY, and RS, data analysis; MZ, data analysis and writing; JM and JL, MS typing;KH and TEW, genetic cross and writing; BH, DNA extraction; GM and PA,data ... zinc fingerproteins and their binding characteristics, and NIAID intramural editorBrenda Rae Marshall for assistance.Author details1Laboratory of Malaria and Vector Research, National Institute ... datanormalizationThe PFSANGER Genechipđwas purchased from Affy-metrix,Inc.(SantaClara,CA,USA),andarrayhybridi-zation was performed at the microarray facility of theNational Cancer Institute...
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Báo cáo y học: " High cell density and latent membrane protein 1 expression induce cleavage of the mixed lineage leukemia gene at 11q23 in nasopharyngeal carcinoma cell line" ppt
... 2009, 12 4:2 016 -2025.doi :10 .11 86 /14 23- 012 7 -17 -77Cite this article as: Yee and Sim: High cell density and latent membrane protein 1 expression induce cleavage of the mixed lineage leukemia gene at 11 q23 in nasopharyngeal ... rearrange-ments. Among them, chromosome gains are commonlyfound in 12 p 11. 2-p12, 12 q14-q 21, 2q24-q 31, 1q 31- qter,3q13, 1q13.3, 5q 21, 6q14-q22, 7q 21, 8q 11. 2-q23 and 18 q12-qter. On the other hand, chromosomedeletions ... inhibitor(Fig.2,lanes 5and6 ).This finding suggests that CAD is involved in cleavage of the MLL bcr resulted from high cell density- inducedapoptosis. Expression of LMP1 gene induces apoptosis in SUNE1cells In order to investigate...
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Báo cáo y học: " High efficient isolation and systematic identification of human adipose-derived mesenchymal stem cells." ppsx
... article as: Yang et al.: High efficient isolation and systematic identification of human adipose-derived mesenchymal stem cells. Journal of Biomedical Science 2011 18:59.Submit your next manuscript ... 18:59http://www.jbiomedsci.com/content/18/1/59Page 6 of 9 RESEARC H Open Access High efficient isolation and systematic identification of human adipose-derived mesenchymal stem cellsXu-Fang Yang1,2,XuHe1*, Jian He1, ... H, Li Y, Li G, Cui L, Liu W, Cao Y: Evaluation of the viability and osteogenic differentiation of cryopreserved human adipose-derived stem cells. Cryobiology 2008, 57:18-24.18. Chen MY, Lie...
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Báo cáo y học: " Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare: results from a large prospective cohort study" pot
... pregnancy and early or late postpartumMean change in IgG1 and IgG2 galactosylation during pregnancy and early or late postpartum. (a) Mean change in IgG1 and IgG2 galactosylation (ì100%) during pregnancy ... during pregnancy and postpartumMean galactosylation of IgG1 and IgG2 in cases and controls during pregnancy and postpartum. IgG1 (a) and IgG2 (b) galactosylation levels (in percentages) increase ... IgG galactosylation changes with pregnancy-induced improvement and postpartum flare in RA-patients.Since IgG galactosylation was associated with sialylation, also sialylation seems to be an...
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Báo cáo y học: "Acute lung inflammation and ventilator-induced lung injury caused by ATP via the P2Y receptors: an experimental study" pdf
... derangement in the 200 mM α,β-MeATP-treated lungs. Bars = 100 μm in the upper panels, and = 50 μm in the lower panels. B. Immunohistochemistry of the P 2Y 2 and P 2Y 4 receptors. P 2Y 2 and P 2Y 4 receptors ... fluid status in the lung, the lung edema caused by ATP might be another mechanismof VILI. The antagonism of ATP- P 2Y signaling by PPADS blocked the production of IL-6 induced by mechanical ventilation,illustrating ... mechanical ventilation, 3) determinedwhether a purinergic receptor antagonist can alleviate the lung injury caused by mechanical ventilation, and 4) doc-umented the expression of the P 2Y 2 and...
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Báo cáo y học: " Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis" ppt
... sets, many representingfetal and embryonic hemoglobins (h emoglobins δ, μ, g, and θ), erythrocyte structural proteins (erythrocytemembrane protein band 4.2), surface proteins (glyco-phorins A, ... Further-more, an expansion of precursor cells and upregulationof an erythropoiesis gene-expression signature occurredpredominantly in individuals with sJIA and anemia.Strikingly, a discrepancy was noted ... and anti-CD19-APC; (f) anti-CD34-FITC, anti-CD105-PE, anti-CD45-PerCP, and anti-CD33-APC; (g) anti-Lin-FITC,anti-HLA-DR-PE, and anti-CD11c-APC; and (h) anti-Lin-FITC, anti-BDCA4-PE, and anti-CD11c-APC....
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Báo cáo y học: "Bone mineral density and body composition in postmenopausal women with psoriasis and psoriatic arthritis" doc
... treated with etanercept,adalimumab and infliximab [20,21].Theaimofthepresentstudywastoanalyzebone density and body co mposition in postmenopausal women with psoriasis, psoriatic arthritis and in ... bone mineral content; BMD, bone mineral density; Ps, psoriasis; PsA, psoriatic arthritis.Table 3 Body composition, overfat and sarcopeniaaccording to the body fat normality curves measured byDXAPsA ... article as: Pedreira et al.: Bone mineral density and body composition in postmenopausal women with psoriasis and psoriatic arthritis. Arthritis Research & Therapy 2011 13:R16.Pedreira et al....
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Báo cáo y học: "Mast cell tumours and other skin neoplasia in Danish dogs - data from the Danish Veterinary Cancer Registry" potx
... in dogs. Onderstepoort J Vet Res 1983,50:19 9-2 20.doi:10.1186/175 1-0 14 7-5 2-6 Cite this article as: Brønden et al.: Mast cell tumours and other skin neoplasia in Danish dogs - data from the Danish ... neoplasms located in the skin wassimilar to data of a Norwegian study [1]. In an Ameri-can study including both benign and malignant neo-plasms, the proportion of tumours located in the skin was much ... entity, and data are collected pro-spectively. In contrast to other veterinary and human cancer registri es DVCR comprises bo th benign and malignant neoplasms, and neoplasms diagnosed usingother...
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Báo cáo y học: "A3 adenosine receptors and mitogen-activated protein kinases in lung injury following in vivo reperfusion" pps
... interventions for attenuation ofIR lung injury remain a focus of intense research. Mitogen-activated protein kinases (MAPKs) are serine-threo-nine protein kinases that participate in anti-inflammatory/inflammatory ... 3-ethyl-5-benzyl-2-methyl-4-phenylethynykyl-6-phenyl-1,4-(±)-dihy-dropyridine-3,5 dicarboxylate (MRS1191; 1 mg/kg intrave-nously).Assessment of injury and apoptosisFor light microscopy, samples of lung ... attenuate injury in a warm IR ratmodel [8] and in canine lung transplantation-related IR [9].Similarly, inhibiting JNK activity during periods of bothischemia and reperfusion attenuated lung injury...
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Báo cáo y học: "Human defensins 5 and 6 enhance HIV-1 infectivity through promoting HIV attachment" ppsx
... al. Retrovirology 2011, 8: 45 http://www.retrovirology.com/content/8/1/ 45 Page 9 of 10 RESEARC H Open AccessHuman defensins 5 and 6 enhance HIV- 1 infectivity through promoting HIV attachmentAprille ... gonorrhoeae-Induced Human Defensins 5 and 6 Increase HIV Infectivity: Role in Enhanced Transmission. J Immunol 2008,180(9) :61 76- 61 85. 18. Fan SR, Liu XP, Liao QP: Human defensins and cytokines in vaginal ... viral infec tion they overrode the HIV enhancing effect of defensins. HD5 and HD6 enhanced HIV infectivity by promoting HIV attachment to targetcells. Studi es using fluorescent HIV containing Vpr-GFP...
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Báo cáo y học: " pG island density and its correlations with genomic features in mammalian genomes" pps
... CGI density and genomic features in ten mammalian genomes (including platypus). Additional datafile 3 shows the correlations between intergenic CGI density and genomic features in nine mammalian ... genome features. Results: In this study, we performed a systematic analysis of CpG islands in ten mammalian genomes. We found that both the number of CpG islands and their density vary greatly amonggenomes, ... (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.CpG island density& lt;p>A systematic analysis of CpG islands...
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