Regulation of cytokines by small RNAs during skin inflammation potx

... cited. Review Regulation of cytokines by small RNAs during skin inflammation Rasmus O Bak and Jacob G Mikkelsen* Abstract Intercellular signaling by cytokines is a vital feature of the innate ... expression by small RNAs - possible roles of miRNAs in psoriasis An extensive and important group of non-coding RNAs (ncRNAs) appeared with the discovery of miRN...

Ngày tải lên: 10/08/2014, 05:21

... of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell 102, 849–862. 21 Hofmann TG, Moller A, Sirma H, Zentgraf H, Taya Y, Droge W, Will H & Schmitz ML (2002) Regulation of ... Ritterhoff S, Vichalkovski A, Del Sal G & Schmitz ML (2006) Autoregulatory control of the p53 response by caspase-mediated processing of HIPK2. EMBO J 25, 1883–1894. 2...

Ngày tải lên: 16/03/2014, 00:20

... 42 levels is mainly achieved by modulation of secretases, namely by the induction of a-secretase activity, by inhibition of b-secretases and ⁄ or c-secretases, or by a combination of both. This study ... Koryakina et al. Regulation of secretases by retinoic acid FEBS Journal 276 (2009) 2645–2655 ª 2009 The Authors Journal compilation ª 2009 FEBS 2651 Regulation of se...

Ngày tải lên: 16/03/2014, 01:20

... suggest the involvement of the NF-jB pathway in the degradation of DNp63a. The level of DNp63a determines cell fate after TNF-a treatment During TNF-a treatment, a small percentage of ME180 cells undergo ... destabilizes DNp63a by both proteasomal and caspase-dependent degradation pathways. The degradation of DNp63a by TNF-a was attenuated by inhibition of NF-jB, sug- ge...

Ngày tải lên: 16/03/2014, 06:20

... involved in up -regulation of human deoxyribonuclease II transcription during differentiation of HL-60 cells San-Fang Chou 1 , Hui-Ling Chen 2 * and Shao-Chun Lu 1 * 1 Department of Biochemistry ... Coaddition of the two antibodies resulted in the loss of bands C1, C2, and C3 (lane 13). In contrast, the use of a control monoclonal antibody against SREBP did not affect the forma...

Ngày tải lên: 23/03/2014, 17:21

... representative of all the samples analyzed, as in only three preparations out of the six analyzed was a decrease of mRNA transcripts observed. Fig. 3. Western immunoblotting of protein homogenates of human immature ... modulation of the cytokine network and a decrease of T- and B-cell proliferation have been described in vitro [9]. A reduction of the cytolytic activity of na...

Ngày tải lên: 22/02/2014, 07:20

Ngày tải lên: 23/02/2014, 02:20

... run-off coefficient. The conception of run-off coefficient is calculated by the ratio between suface water (mm) by rainfall and the amount of water (mm) σRoff = Y/P, where: Y: run-off by rainfall; ... structure by waterproof material which is tiny. The rate of rigid surface increase which is opposite with the loss of water therefore it is danger of the amount of dr...

Ngày tải lên: 14/03/2014, 15:20

... requirement of NAGK for NAGS activity, the absence of NAGS increased the activity of NAGK by approximately twofold, possibly reflecting inhibition of NAGK in the NAGS/NAGK complex. The presence of NAGS ... expression of the inserted genes is put under the control of a GAL promoter. The BY4 /HP73 and HP72/ BY5 primer pairs were used to construct pHP17, BY4 / HP79, and HP80 /B...

Ngày tải lên: 23/03/2014, 21:20

... majority of countries. Figure 4 Regulation of the Importation / Exportation of Reproductive Egg Cells Regulated by Law Binding Guidelines Non-Binding Guidelines Not Regulated Prohibited by ... authorities of the origin country that the requisites required by Spanish law have been fulfilled, on completeness (by the sample) of requisites asked to donors by our law...

Ngày tải lên: 28/03/2014, 16:20