Characterization of Fabry mice treated with recombinant adeno-associated virus 2/8-mediated gene transfer pdf

... the original work is properly cited. Research Characterization of Fabry mice treated with recombinant adeno-associated virus 2/8-mediated gene transfer Jin-Ok Choi, Mi Hee Lee, Hae-Young Park ... Immunohistochemistry of CD77/Gb3 in the kidney of Fabry mice. (A) Wild-type mice unstained, (B) staining appeared in glomeruli and tubules of untreated Fabry mi...

Ngày tải lên: 10/08/2014, 05:21

... a r s , t h e i n c i d e n c e of MACE in the group treated with ZES was 10% and 17.8% (p:0.003) was recorded for the group treated with PES. The incidence of CABG (2.6% vs 6.9%, p:0.002), ... outcome of ZES and PES in unselected patients treated in daily practice remains controversial. The long-term safety of DESs remains in question (10-11). Despite the results of...

Ngày tải lên: 25/10/2012, 11:18

... (Figures 9 and 10). Discussion Benign chondroblastomas can often be treated with sim- ple curettage with or without bone grafting [4,14], or with other adjuvant therapies including alcohol, cryotherapy ... has been suc- cessfully utilised with bone transport in a series of 5 proximal tibial GCTs, with a mean defect of 5.7 cm [38], and in 7 distal femoral tumors with defects...

Ngày tải lên: 20/06/2014, 04:20

Ngày tải lên: 05/08/2014, 09:46

... nephrectomy combined with lymphadenect- omy was performed. Pathological examination resulted in diagnosis of this case as CDC with tubulopapillary archi- tecture consisting of tumor cells with eosinophilic ... nephrectomy, this case was treated with sunitinib rather than systemic chemotherapy, considering her poor performance status. After 4 courses of sunitinib therapy with...

Ngày tải lên: 09/08/2014, 02:20

... both sides of the norm, the MC predicted doses were lower for the majority of the patients (15 out of 22) for the bladder and MC doses were higher for the majority of the patients (14 out of 22) ... 8 of 17 (page number not for citation purposes) Results Monte Carlo Verification of Film Measurements Figure 1 summarizes the gamma analysis of eleven of the patient plans (inclu...

Ngày tải lên: 09/08/2014, 09:22

... lesion with a magnetic resonance imaging (MRI) scan, which revealed a space-occupying cystic lesion of maximum diameter of 5 cm l ocated in the tail of the pancreas with calcifications of the ... on the location of the tumor, represents the procedure of choice. In general, the prognosis, even in the case of a malignant SPT with metastasis, is favor- able. Some patients wi...

Ngày tải lên: 11/08/2014, 02:22

... RP (2000) Length of CTGÆCAG repeats determines the influence of mismatch repair on genetic instability. J Mol Biol 299, 865–874. 11 Wells RD (1996) Molecular basis of genetic instability of triplet ... expansion of triplet repeats such as CAG, CGG and GAA, which are associated with human hereditary disease genes, helped in understanding the possible mechanism of slippage and the...

Ngày tải lên: 07/03/2014, 06:20

... Zn 2+ [8], and a number of APs require the addition of Mg 2+ to achieve maximum activity. Others have proposed that the first duplication of the ancestral AP gene during the evolution of the AP gene family ... joining the two AP monomers of AP together [32]. In a vari- ety of human cancer cell lines and sera, the Kasahara AP isoform has been found to consist of heterodimers...

Ngày tải lên: 07/03/2014, 17:20

... of 8 have reported that the polyphosphatase encoded by the ppx gene is required along with the ppk gene to protect the cell from the toxic effects of heavy metals [23-25]. While w e did not genetically ... transformation with transcriptional and translational enhanced vectors designed for the expression of metallothionein and polyphosphate kinase provided high transgene transcri...

Ngày tải lên: 23/03/2014, 22:20