Báo cáo y học: "Pre-clinical development as microbicide of zinc tetra-ascorbo-camphorate, a novel terpenoid derivative: Potent in vitro inhibitory activity against both R5- and X4-tropic HIV-1 strains without significant in vivo mucosal toxicity" docx

... purposes) AIDS Research and Therapy Open Access Research Pre-clinical development as microbicide of zinc tetra-ascorbo-camphorate, a novel terpenoid derivative: Potent in vitro inhibitory activity against ... leucocytes infiltration, vascular congestion and oedeme, were calculated as the mean of the scores estimated at the cervicovagina, midvagina and...

Ngày tải lên: 10/08/2014, 05:21

... trauma, during the preceding year. His serum prolactin was massively increased and a magnetic resonance imaging (MRI) scan of the head demonstrated a pituitary mass consistent with a prolactinoma. ... prolactinoma was present during the initial presentation and was the cause of his anaemia. Conclusion: This case highlights the importance of fully evaluating and investigating...

Ngày tải lên: 11/08/2014, 14:21

... Okuno T, Tamura T, Yamamori M, Chayahara N, Yamada T, Miki I, Okamura N, Kadowaki Y, Shirasaka D, Aoyama N, Nakamura T, Okumura K, Azuma T, Kasuga M, Sakaeda T. Favorable genetic polymorphisms ... Ehninger G, Stoehlmacher J. Phar- macogenetic analyses of a phase III trial in metastatic gastroesoph- ageal adenocarcinoma with fluorouracil and leucovorin plus either oxaliplatin or c...

Ngày tải lên: 25/10/2012, 10:51

... S., Matsufuji, T., Miyazaki, Y. , Murakami, Y. , Atkins, J.F., Gesteland, R.F. & Hayashi, S. (1995) Autoregulatory frame- shifting in decoding mammalian ornithine decarboxylase anti- zyme. ... Murakami, Y. , Matsufuji, S., Kameji, T., Hayashi, S., Igarashi, K., Tamura, T., Tanaka, K. & Ichihara, A. (1992) Ornithine decarboxylase is degraded by the 26S proteasome without ubiqui...

Ngày tải lên: 22/02/2014, 04:20

... information towards the design and synthesis of new molecules with higher binding affinity and enhanced stability against biological degradation and possibly biological activity. The impact of Aib introduction ... studies and biological activity evaluation of new CRH analogues are in progress in our laboratory. Fig. 4. (A) Surface electrostatic potentials of CRH analog...

Ngày tải lên: 17/03/2014, 10:20

... the main contamination, seen in lane 1, run s only m arginally above the hA2aR fusion pro tein and is the main band in lane 2. In this pu ri®cation, 7% of speci®c ligand binding sites loaded ... fusion protein was characterized by ligan d b inding analyses to judge its identity and integrity. Binding of the antagonist [ 3 H]ZM241385 was speci®c and saturable for both membran...

Ngày tải lên: 24/03/2014, 00:21

... malignancies (especially in the pancreas) and disseminated carcinoma- tosis. Also, there are a number of abnormal endocrine conditions including hypothyroidism and hyperthyroid- ism, hyperparathyroidism, hypopituitarism, ... brain magnetic resonance imaging (MRI) scans, and in late onset cases indices assessing malig- nancy. Suicide Today we know that suicide is a complex and...

Ngày tải lên: 08/08/2014, 23:21

... between radiographic grading of osteoarthritis and the biochemical markers for arthritis in knee osteoarthritis Masaaki Takahashi, Kenichi Naito, Masashi Abe, Tomokazu Sawada and Akira Nagano Department ... pyridinoline were corrected by urinary creatinine. The intra-assay and interassay coefficients of variance were 6.4% and 5.9%, respectively. Serum YKL-40 Serum YKL-40 was mea...

Ngày tải lên: 09/08/2014, 01:23

... treatment and centre as main effects, whereas baseline actual pain was used as a covariate. Data from small centres were pooled using a predefined algorithm. APID, AVPID and WPID were analyzed at ... day of treatment. Secondary variables included evaluation of treatment over 7 days during the multiple-dose pain assessment phase. Patients rated actual pain intensity, average pa...

Ngày tải lên: 09/08/2014, 07:20

... design, analysis and interpretation of data, manuscript preparation, and statistical analysis. SKT partici- pated in acquisition of data, analysis and interpretation of data, and manuscript preparation. ... interpretation of data, manuscript preparation, and statis- tical analysis. J-PP participated in study design, analysis and interpretation of data, and manuscri...

Ngày tải lên: 09/08/2014, 10:23