... treatment.Recent analyses in a large cohort of clinical trial patients haverevealed that baseline disease activity is already somewhatrelated to disease activity at 1 year of therapy, especially ... lesseasy to standardize than many laboratory measures.Any biological marker will therefore have to prove its value in relation to clinical markers, and not necessarily vice versa.Nevertheless, to ... Udagawa N, Takami M, KotakeS, Nakagawa N, Kinosaki M, Yamaguchi K, Shima N, Yasuda H,Morinaga T, Higashio K, Martin TJ, Suda T: Tumor necrosisfactor alpha stimulates osteoclast differentiation...