Báo cáo y học: " Acceptability of Carraguard, a candidate microbicide and methyl cellulose placebo vaginal gels among HIV-positive women and men in Durban, South Africa" pps
Báo cáo y học: " Acceptability of Carraguard, a candidate microbicide and methyl cellulose placebo vaginal gels among HIV-positive women and men in Durban, South Africa" pps
... of Carraguard, a candidate microbicide and methyl cellulose placebo vaginal gels among HIV-positive women and men in Durban, South AfricaGita Ramjee*1, Neetha S Morar1, Sarah Braunstein2, ... safety and acceptability among sexually active and abstinent women. However there is paucity in the data on safety and acceptability of the potential microbicides among HIVpositive women and men. ... May 2002 to July 2003 to evaluate the safety and acceptability of Carraguard among HIV positive sexuallyabstinent men and sexually active and abstinent HIV-pos-itive women in Durban, South Africa....
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Báo cáo y học: " Acceptability of cancer chemoprevention trials: impact of the design" docx
... legislation related to medical research and did not require a National or local IRB approval since data were strictly anonymous. Taking in account the advice of a local Ethical Board, an information ... critical ethical issue about clinical trials is the acceptability of randomization and how lay people understand it [10]. In our questionnaire that issue was framed as: “To test the actual efficacy ... univariate analy-sis among men, tobacco exposure was the only factor associated with the willingness to participate (OR=2.3 95%CI 1.4-3.9). In a multivariate analysis among women, for lung cancer...
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Báo cáo y học: "Effect of allergen-specific immunotherapy with purified Alt a1 on AMP responsiveness, exhaled nitric oxide and exhaled breath condensate pH: a randomized double blind study" ppsx
... glycerinatedsaline.Data analysisAn intention-to-treat approach was followed in the ana-lysis of efficacy data. All patients with a baseline and atleast one postrandomization measurement wereincluded in the ... wererepeated.The dose of intranasal or ICS (if used) was maintainedunchanged during the study. Salbutamol metered-doseinhaler, oral antihistamines and intranasal antihistamineswere used on an “as-needed” ... medication and of mild,moderate or serious severity.Specific immunotherapyAlternaria alternata extract and nAlt a1 were producedby Diater (Madrid, Spain). Raw material containingspores and mycelia...
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Báo cáo y học: "Analysis of TNFAIP3, a feedback inhibitor of nuclear factor-κB and the neighbor intergenic 6q23 region in rheumatoid arthritis susceptibility" pot
... and in the analysis and interpretation of results. JJG-Rcoordinated the acquisition of clinical data and collection of samples, and participated in the analysis and interpretation of results. AG ... participated in the design of the study and in thecoordination of acquisition of clinical data and collection of samples, and supervised genotyping, statistical analysis, inter-pretation of ... contributionsRD-G participated in design of the study, genotyped the sam-ples, and participated in the interpretation of the results and in writing the manuscript. MC participated in the statistical anal-ysis...
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Báo cáo y học: " Review of Anton A. Niekerk and Loretta M. Kopelman (eds.) Ethics and AIDS in Africa: The Challenge to our Thinking" pptx
... terrifyingsocial impact HIV/AIDS is currently having in sub-Saha-ran Africa. There is general condemnation of the lack of leadership and intransigence of the South African govern-ment in its approach ... conflicts of value. AIDS: the world's deadliest epidemic since theBlack Plague of the 14th century. And Africa: cradle of humankind, burdened by colonization, famine, poverty and civil war. In ... internationalfunding – they have an ethical duty to create policies and programs that sustain global AIDS initiatives. David Res-nik claims that pharmaceutical companies have ethicalresponsibilities towards those...
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Báo cáo y học: " Roles of XB130, a novel adaptor protein, in cancer" pps
... oncoprotein in cancer. A deeper understanding of these mechanismsBinding PartnerpYpYXB130pYpYXB130Binding Partnerinactiveactivetyrosine kinase-mediated signalingCell cycleSurvivalMigrationInvasiontranscriptional ... XB130(818aa) and AFAP (730aa) is the presence of potential SH2, SH3-binding sites and two PH domains. A coiled-coil domain of XB130 shares partialsimilarity with the leucine zipper domain and in AFAP.Shiozaki ... goodexample of how adaptor proteins a re involved in signaltransduction is the activation of c-Src protein-tyrosinekinases by adaptor proteins via prote in- protein interac-tions. Adaptor proteins are...
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Báo cáo khoa học: Interaction of ostreolysin, a cytolytic protein from the edible mushroom Pleurotus ostreatus, with lipid membranes and modulation by lysophospholipids pptx
... [11].Cytotoxic activityCytotoxic activity of ostreolysin was assayed using HT 1080(human fibrosarcoma cells) and MCF 7 (human breastadenocarcinoma cells). After thawing, cells were grown for a week in Eagle’s ... acid,oleoyl (lyso-PtdOH), sphingosine 1-phosphate (Sph1P),myristic, palmitic and stearic acid, dilauroyl, dimyristoyl, dipentadecanoyl, dipalmitoyl and distearoyl phosphatidyl-choline, and human ... sediments and supernatants obtained were analyzed. (A) lane 1, Pharmacia low molecular mass standards; lane 2, ostreolysin (noncentrifuged); lane 3, ostreolysin (supernatant); lane 4, ostreolysin (sediment);...
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Báo cáo y học: "Effectiveness of injectable risperidone long-acting therapy for schizophrenia: data from the US, Spain, Australia, and Belgium" ppt
... schizophrenia: data from the US, Spain,Australia, and Belgium. Annals of General Psychiatry 2011 10:10.Lambert et al. Annals of General Psychiatry 2011, 10:10http://www.annals-general-psychiatry.com/content/10/1/10Page ... onmental illness and wellness. An international survey Indianapolis, IN: Eli Lilly and Company; 2010.3. Eli Lilly and Company: Keeping care complete: a physicians’ perspective onmental illness and ... US,Spain, Australia, and Belgium, respectively, had ≥1 post-baseline visit and were included in the analysis of psychiatric hospitalization rates. Hospitalization rates decreased significantly in...
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Báo cáo y học: "Analysis of bronchoalveolar lavage fluid proteome from systemic sclerosis patients with or without functional, clinical and radiological signs of lung fibrosis" pot
... Cardiovascular Sciences, University of Pavia, Via Taramelli 5, 27100 Pavia, Italy2Department of Biochemistry, University of Pavia, Via Taramelli 5, 27100 Pavia, Italy3Department of Internal ... microscopic and cultural examination of common bacteria and fungi, and of direct acid-fast bacilli smears (Kinyoun method) and culturesfor mycobacteria, and for the microscopic examination of Pneumocystis ... purposes)glycoprotein, calumenin, cytohesin-2, Cal B, and mtDNATOP1.Haptoglobin and α1-acid glycoprotein are positive acute-phase proteins, whose plasma concentrations increase duringinflammation...
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Báo cáo y học: "Association of the diplotype configuration at the N-acetyltransferase 2 gene with adverse events with co-trimoxazole in Japanese patients with systemic lupus erythematosus" pps
... Manabu Kawamoto1, Yasuhiro Katsumata1, Kae Takagi1, Ayako Nakajima1, Tadayuki Mitamura2, Akio Mimori3, Masako Hara1 and Naoyuki Kamatani11Institute of Rheumatology, Tokyo Women& apos;s ... isoniazid and rifampicin-induced hepatotoxicity. Int J Tuberc Lung Dis 2000,4:256-261.15. Tanaka E, Taniguchi A, Urano W, Nakajima H, Matsuda Y, Kitamura Y, Saito M, Yamanaka H, Saito T, Kamatani ... Tokyo, 151-8528, Japan3Department of Rheumatology, International Medical Center of Japan, Toyama, Shinjuku-ku, Tokyo, 162-8855, JapanCorresponding author: Yasushi Kawaguchi, y- kawa@ior.twmu.ac.jpReceived:...
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