... details1Department of Neuroscience, Section of Psychiatry, University of Genova,Genoa, Italy.2Department of Hematology and Oncology, Section of Semeiotics and Medical Methodology I, University of Genova, ... study rath eraimed to investigate the role of the combination of thetwo drugs, and the unusual choice of the SNRI duloxe-tine (mainly metabolized by CYP1A 2 and CYP2D6) wasessentially due ... mg/day to commonly used anti-Parkinsonian drugs,significantly improved the primary symptoms of patientswith advanced Parkinson’s disease, possibly by activatio n of dopamine synthesis, inhibition...