Ophthalmic Drug Delivery Systems - part 9 pot

... S. G. ( 199 9). Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina. Proc. Natl. Acad. Sci. USA, 96 (17) :99 20 99 25. 130. ... ( 199 6). Phosphorothioate-modified oli- godeoxyribonucleotides, III. NMR and UV spectroscopic studies of the Rp- Rp, Sp-SP, and Rp-Sp duplexes, [d(GGSAATTCC)]2, derived from diaster- eome...

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... practically unaltered. The corneal and conjunctival penetration of 4-phenylazobenzyloxy- carbonyl-l-Pro-l-Leu-Gly-l-Pro-d-Arg (Pz-peptide) and its effect on the corneal and conjunctival penetration ... near future. We hope that novel drug delivery systems will be developed to deliver potent polypeptide drugs through the ocular route. REFERENCES 1. Lee, V. H. L. ( 198 7). Ophthalmic de...

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... ( 199 6). Phosphorothioate-modified oli- godeoxyribonucleotides, III. NMR and UV spectroscopic studies of the Rp- Rp, Sp-SP, and Rp-Sp duplexes, [d(GGSAATTCC)]2, derived from diaster- eomeric O-ethyl ... cationic lipid-protamine-DNA (LPD) complexes. Gene Ther., 4 (9) : 891 90 0. 176. Li, S., Rizzo, M. A., Bhattachrya, S., and Huang, L. ( 199 8). Characterization of cationic lipid-protamine-DNA...

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... formation of aqueous humor (Caprioli, 199 2). Na + /K + -ATPase (Usukura et al., 198 8; Okami et al., 198 9; Martin-Vasallo et at., 198 9), H + /K + -ATPase (Fain et al, 198 8) and active ascorbate transport ... Brittam 96 Freeze-Drymg/Lyophilization of Pharmaceutical and Biological Prod- ucts, edited by Louis Rey and Joan C May 97 . Percutaneous Absorption- Drugs-Cosmetics...

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... consideration in topical ocular drug delivery. Clin. Exp. Pharmacol. Physiol., 27:558. 8. Schoenwald, R. D. ( 199 3). Ocular pharmacokinetics/pharmacodynamics, Ophthalmic Drug Delivery Systems (A. K. Mitra, ... ( 199 1). A phenotype conferring selective resistance to lipophilic antifolates in Chinese hamster ovary cells. Cancer Res., 51(11); 294 9– 295 9. Sherman, S. H., Green, K.,...

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... injection location and the retinal permeability of the drug. If the drug has a low retinal permeability, then the half-life of the drug in an aphakic eye is highly depen- dent on the distance between the injection ... injection, increased as the drug diffusivity was reduced. Furthermore, the rate of drug elimination, which is inversely related to the drug s elimination half- life, de...

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... applied drugs in the rabbit. Pharm. Res. 15:1882–1887, 199 8. 50. Yen, W C., and Lee, V. H. L. Role of Na + in the asymmetric paracellular transport of 4-phenylazobenzyloxycarbonyl-L-Pro-L-Leu-Gly-L-Pro-D-Arg across ... Pharm. 161:1 69 178, 199 8. 29. Valenta, C., and Wedenig, S. Effects of penetration enhancer on the in vitro percutaneous absorption of progesterone. J. Pharm. Pharmacol. 49:...

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... protein drugs, Adv. Drug Delivery Rev., 8:331–3 39. 81. Chiou, G. C. Y. ( 199 4). Systemic delivery of polypeptide drugs through ocular route, J. Ocul. Pharmacol., 10 :93 99 . 82. Morgan, R. V. ( 199 5). Delivery ... R. ( 199 8). Ophthalmic drug delivery systems recent advances, Prog. Retinal Eye Res., 17:33–58. 95 . Robinson, J. C. ( 199 3). Ocular anatomy and physiology rel...

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... Lundin, S., and Atursson, P. ( 199 0). Absorption of vasopressin analogue, 1- desamino-8-D-arginine-vasopressin (dDAVP), in human intestinal epithelial cell line, CaCO-2, Int. J. Pharm., 64:181. 43. ... and Vilhardt, H. ( 198 3). Vasopressin effects on isolated non-pregnant myometrium and uterine arteries and their inhibition by deamino-ethyl-lysine-vasopressin and dea- mino-ethyl-oxytocin,...

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