Neuroimmunology in Clinical Practice - part 2 pdf
Neuroimmunology in Clinical Practice - part 2 pdf
... whereas animals deficient in IL- 12 alone develop severe dis- ease. Interleukin -2 3 induces IL-17 production by T cells. IL-17 is expressed in brain lesions and appears to be a regulator of CNS in ammation. T ... HLA-B HLA-C HLA-X HLA-E HLA-H HLA-A HLA-F HLA-G MOG αβ 21 -OH C4 BFC2 20 00 3000 4000 Telomere kb Fig. 3.1 The figure depicts the MHC class II, class III, and class I regions...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 3 pdf
... anti-CD40L/-CD154 (IDEC-131); anti-IL- 12, anti-CD6; anti-CD3 (OKT3); anti-Vβ5 .2/ 5.3 + T cells; anti-CD4; integrin inhibitors Lymphocyte-specific cytoplasmic protein – tyrosine kinase P56lck; zeta-associated protein ... a 25 -year-old male with secondary-progressive MS (a, b, c) showing homogeneously enhancing lesions (a) and from a 29 -year-old female with relapsing-remitting MS (d, e, f...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 6 pdf
... consistent benefit include indomethacin, somatostatin analogs, caffeine, ergot alkaloids, and nocturnal desmopressin. L-threo-3, 4-dihydroxyphenylserine is used in the rare but dis- tinctive entity, ... molecule BB-1, the ligands CTLA-4 and CD28 and their mRNAs in chronic in am- matory demyelinating polyneuropathy. Brain, 123 , 1660–6. Mygland, A. and Monstad, P. 20 01. Chronic polyneur...
Ngày tải lên: 10/08/2014, 00:20
Chapter 003. Decision-Making in Clinical Medicine (Part 2) pdf
... Decision-Making in Clinical Medicine (Part 2) The following three examples introduce the subject of clinical reasoning: A 46-year-old man presents to his internist with a chief complaint ... therefore more influential on clinical judgments. The third commonly used cognitive shortcut, the anchoring heuristic, involves estimating a probability by starting from a familiar po...
Ngày tải lên: 06/07/2014, 08:20
Chapter 065. Gene Therapy in Clinical Medicine (Part 2) pdf
... transcription factor complex involved in Chapter 065. Gene Therapy in Clinical Medicine (Part 2) Figure 6 5-1 Indications in gene therapy clinical trials. The chart divides clinical gene transfer ... splenomegaly, rising white counts, and the emergence of a single clone of T cells. In these children, the retroviral vector had integrated within a gene, LMO -2 (LI...
Ngày tải lên: 07/07/2014, 01:20
Neuroimmunology in Clinical Practice - part 1 ppt
... (McKerracher and Winton, 20 02) . NICP_C 02 04/05 /20 07 12: 27PM Page 15 Foreword Neuroimmunology in Clinical Practice provides a use- ful and comprehensive review of the field of clinical neuroimmunology. In addition ... molecules are single-chain glycoproteins that pair with β 2 -microglobulin. In contrast, class II molecules are heterodimeric, com- posed of α and β chain...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 4 pot
... recent clinical and paraclinical studies of NMO was reported by investigators at the Mayo Clinic (Lennon et al., 20 03, 20 04, 20 05; Lucchinetti et al., 20 02; Pittock et al., 20 05, 20 06a,b; Wingerchuck ... IgG/Albumin ratio 60–80% 21 24 % 16 20 % 14– 42% 6–10% CSF/Serum IgG index 88–94% 44–55% 15 20 % 43–57% 3–18% IgG synthetic rate 88–96% 27 –67% 16–18% 29 % 4– 12% Oligoclona...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 5 potx
... identified. Inter- leukin 23 (IL -2 3 ) may play an important role in the early effector phase of immune-mediated peripheral nerve demyelination in EAN, as well as in human GBS. IL -2 3 is highly expressed in ... sclerosis beginning in infancy. J Child Neurol, 2( 4), 25 2–6. Shintani, S., Fumimura, Y. and Shiigai, T. 20 01. Acute disseminated encephalomyelitis following aseptic m...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 7 pps
... dermatomyositis, and inclusion-body myositis. N Engl J Med, 325 , 1487–98. Dalakas M.C. 20 02. Muscle biopsy findings in inflam- matory myopathies. Rheum Dis Clin North Am, 28 , 779–98. Dalakas, M.C. 20 04. In ammatory ... directed against signal recog- nition particle proteins (anti-SRP), and antibodies directed against the nuclear protein complex Mi -2 (anti-Mi -2 ) . The antisyntheta...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 8 ppt
... GluR1 AGNA-1; ANNA-1 ,2, 3; PCA -2 ; Ma2; CRMP-5; VGCC (P/Q>N-type) Amphiphysin CRMP-5; ANNA-1; 2, PCA -2 CRMP-5; recoverin CRMP-5; VGCC; amphiphysin; ganglionic AChR; VGKC; ANNA-1 ,2 ANNA-1; CRMP-5; ... Ma2; neuropil AGNA-1; ANNA-1 ,2, 3; PCA -2 ; amphiphysin; CRMP-5; ganglionic AChR; VGCC (P/Q or N); striational; GAD65; EFA6A Ma2; ANNA-1 CRMP-5 VGKC PCA-1 ,2, Tr; CRMP-5; AGNA-1; ANN...
Ngày tải lên: 10/08/2014, 00:20