Báo cáo y học: "Targeted enrichment beyond the consensus coding DNA sequence exome reveals exons with higher variant densities" ppt

... Biology 2011, 12:R68 http://genomebiology.com/2011/12/7/R68 Page 2 of 12 RESEARC H Open Access Targeted enrichment beyond the consensus coding DNA sequence exome reveals exons with higher variant ... Bainbridge et al.: Targeted enrichment beyond the consensus coding DNA sequence exome reveals exons with higher variant densities. Genome Biolo...

Ngày tải lên: 09/08/2014, 23:20

... model. This levels the playing field for HAE patients such that any HAE patient can expect the same health care support regar d- less of ability to pay. The only HAE therapy currently licensed for ... per year with incapacity of 4 to 8 days. A step- up therapy with flaring, stabilize, and then reduce back to on demand is in use in many clinics in Canada and depending on the patien...

Ngày tải lên: 08/08/2014, 21:20

... more weight compared to the handled. Furthermore, after the last exposure to the stres- sor, they have higher plasma leptin concentrations. These findings may be relevant to the human condition of ... measured by radioimmunoassay (RIA). Data were statistically analyzed by analysis of variance (ANOVA). Results: Neonatal handling increased the ability of male rats for spatial learni...

Ngày tải lên: 08/08/2014, 21:20

... During the study, the animals were maintained in a facility fully accredited by the Stand- ards Council of Canada (SCC) and the care and use of the animals was conducted in accordance with the guidelines of ... USA. Study procedure All animals were examined twice daily for mortality and signs of ill health or reaction to treatment, except on the days of arrival and necropsy wh...

Ngày tải lên: 08/08/2014, 23:20

... 12-year-old Caucasian boy with a diagnostic delay of 3 years. Conclusion: It is important to know that synovial hemangioma mostly affects the knee joint, showing recurrent bloody effusions without ... which involves the synovia and causes intra-articular bleeding. Only a few of these have been true synovial hemangioma [1,2]. Usually the patient presents with a history of recurrent...

Ngày tải lên: 11/08/2014, 12:20

... of their activity, brought about by a redox- modification at specific cysteine residues mediated by the ferredoxin/thioredoxin system [1]. The activity of each of these enzymes is adjusted by fine-tuning, ... Sauermann 1 1 Plant Physiology, University of Osnabrueck, Germany; 2 Planton GmbH, Kiel, Germany; 3 Plant Physiology, University of Kaiserslautern, Kaiserslautern, Germany Light/dark mo...

Ngày tải lên: 08/03/2014, 09:20

... (AFM); H -DNA; intramolecular triplex DNA; poly- pyrimidine/ polypurine sequence. There is a wealth of evidence indicating that short pyrimidine/purine-biased (Pyr/Pur) mirror symmetry sequences ... (B). Although mirror symmetry may not be necessary for the formation of base triads in the triplex stem [27], some mismatches may occur between the duplex and the third strand in the...

Ngày tải lên: 31/03/2014, 23:20

... which the true mortality rate actually lies. In practice, investigators usually use the 95% CI, the range that includes the true mortality rate 95% of the time. The narrower the CI, the closer the ... tolls by multiplying the observed excess mortality rate (and its CI) by the length of the recall period, and by the estimated total population. The DRC study authors...

Ngày tải lên: 25/10/2012, 10:31

... medical conditions may be delayed. As the physician with the most (and often the only) contact with these patients, psychiatrists need to be vigilant in detecting early signs and symptoms of medical illness ... Patients with bipolar disorder in the general population are likely receiving even less medical care. The significance of this finding is that the psychiatrist may be...

Ngày tải lên: 25/10/2012, 10:51

... due to its methyltransferase activity or the interaction with the PRB motif. Further studies with a methyl- transferase inhibitor specific for the PR domain may help to understand the exact mechanism ... respectively, in the direct admin- istration. The cell death rate was measured by the trypan blue method. For the transfection, the HuH7 cells were trans- fected with...

Ngày tải lên: 25/10/2012, 11:15