Báo cáo y học: "Community transcriptomics reveals universal patterns of protein sequence conservation in natural microbial communities" pdf
Báo cáo y học: "Community transcriptomics reveals universal patterns of protein sequence conservation in natural microbial communities" pdf
... significantly less abundant in the RNA, being
involved in 61% of all decre asing DNA-RNA amino acid
frequency changes. In contrast, frequency increases were
dominated by amino acids enriched in GC: 50% of
increases ... debated. Sequence conservation in highly
expressed proteins has been hypothesized to be driven by
selection acting to minimize the costs of protein misfol...
Báo cáo y học: "High resolution discovery and confirmation of copy number variants in 90 Yoruba Nigerians" pdf
... four Yoruba indi-
viduals, respectively; in the Bentley et al. [20] study, one of
the Yoruba was whole-genome sequenced; the Perry et al.
[13] study examined known copy number variants in 10
Yoruba ... CNV typing
The sample-level event calling thresholds used in the segmen-
tation analysis of the CNV-typing array data were determined
by comparing against reference event calls taken...
Báo cáo y học: " Comparative transcriptomics among floral organs of the basal eudicot Eschscholzia californica as reference for floral evolutionary developmental studies" pps
... yields of 20 to 35
micrograms of total RNAs from approximately 100 mg of
tissues. Approximately 400 ng of total RNAs were used
for cRNA synthesis with Cyanine 3-dCTP and Cyanine5-
dCTP (Perkin-Elmer ... and petals in E. calif ornica, we tried to identify
putative A-function genes on the basis of regulatory
genes expressed in the A domain, hypothesizing that
they may function in...
Báo cáo y học: "Psychiatric disorder as clinical presentation of primary Sjögren’s syndrome: two case reports." pdf
... characterised by a
chronic inflammation of the lachrymal and salivary
glands, which leads to exocrine hypofunction and the
well recognised clinical features of dry eyes (xerophthal-
mia) and dry mouth ... fatigue, myalgia, dry eyes
and dry mouth improved, and her residual depressive
symptoms improved further. She is currently being
maintained on prednisone at a dose of 7.5 mg/day. Her
o...
Báo cáo y học: " Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNF-induced MEK/ERK signalling" ppsx
... significantly cate-
gorized by the molecular function of their protein products into
categories that included hyaluronic acid binding activity
(including Agc1 and Hapln1) and proteinase activity (including
Mmp-9 ... probably
regulated by inhibitory actions of Egr-1 in competition for Sp1
binding sites. Collectively, these data suggest that, in
chondrocytes, alterations in Egr-1 DN...
Báo cáo y học: "Antibodies against the CB10 fragment of type II collagen in rheumatoid arthritis" pdf
... significant finding from our study was that in RA
the use in an ELISA of fragments of the intact CII molecule,
particularly CB10, as antigen markedly increased the sen-
sitivity of detection of antibodies ... and corresponding Coomassie blue protein stain
illustrating the separation of the CB peptides of bovine CII with a linear salt gradient (dotted line). (b) Coomassie bl...
Báo cáo y học: "Reduced number and impaired function of circulating progenitor cells in patients with systemic lupus erythematosus" pot
... amino-terminal two repeats of the
death effector domain (DED), it lacks the carboxy-terminal half
of the proteolytic domain. Caspase 8L binds to the Fas-asso-
ciating protein with death domain ... Luyn
1
, Marc Bijl
2
and Martin C Harmsen
1
1
Department of Pathology and Laboratory Medicine, University Medical Center Groningen, University of Groningen, The Netherlands
2
Department...
Báo cáo y học: "Tandem repeats modify the structure of human genes hosted in segmental duplications" docx
... proteins.
Fifty percent of variable ITRs modify protein sequences
In agreement with an active role in modifying protein
sequences, we found that 50% of the detected ITRs occur in
the coding sequence ... occur in polymorphic human pro-
teins, such as the keratin-associated proteins, the VCX /Y pro-
teins, the nuclear pore interacting proteins, and the prostate-
ovary-testis-...