Báo cáo y học: "Modeling antibiotic and cytotoxic effects of

Báo cáo y học: "Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureu" pot

... Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells. Genome Biology ... presence of IQ-143 (concentrations of a quarter of the minimum inhibitory concentration and twice the minimum inhibitory concentration) as descr...

Ngày tải lên : 09/08/2014, 22:24

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Báo cáo y học: " Rationale for one stage exchange of infected hip replacement using uncemented implants and antibiotic impregnated bone graft"

... Comparison of biofilm-associated cell survival following in vitro exposure of meticil- lin-resistant Staphylococcus aureus biofilms to the antibiotics clindamycin, daptomycin, linezolid, tigecycline ... Identification of bacteria on the surface of clinically infected and non-infected prosthetic hip joints removed during revision arthroplasties by 16S rRNA gene sequenc...

Ngày tải lên : 26/10/2012, 09:53

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Tài liệu Báo cáo Y học: Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells docx

... to the cells, and then the cell suspension was sonicated in a bath-type sonicator for 5min. The amount of protein of the solubilized cells was determined with a bicinchoninic acid protein assay kit ... that the enhancing effect of TS on LPS/IFN-induced NO production is caused by enhancement of iNOS protein induction. Effects of a-T and its derivatives on t...

Ngày tải lên : 22/02/2014, 04:20

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Báo cáo y học: " De novo genome sequence assembly of a filamentous fungus using Sanger, 454 and Illumina sequence data" ppsx

... during the course of our work was the ability to scale beyond 50 M reads, which enabled the direct integration of Illumina PE read data in a single Forge assembly stage. The increased accuracy of EST-to-genome ... alignments, Illumina PE read alignments and the significant increase in contig N50 of the resulting assembly likely resulted from the large amount of p...

Ngày tải lên : 09/08/2014, 20:20

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Báo cáo y học: "Pre-clinical development as microbicide of zinc tetra-ascorbo-camphorate, a novel terpenoid derivative: Potent in vitro inhibitory activity against both R5- and X4-tropic HIV-1 strains without significant in vivo mucosal toxicity" docx

... midvagina and urovagina of the 3 rabbits in each group. The final score is then expressed as mean ± 1 standard deviation of 9 determinations. $ The mean vaginal irritation index corresponds to the ... participated in the Table 2: Scores of epithelium irritation, leucocytes infiltration, vascular congestion and edeme, and vaginal irritation index obtained in three...

Ngày tải lên : 10/08/2014, 05:21

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Báo cáo y học: "Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors" pps

... International Conference on Harmonization and national regulations. The protocol was reviewed and approved by the ethics committee at each participating institution. Study Design In this randomized, ... were 136.5 d ays in the 5 mg/day coh ort and 63.5 days in the 10 mg/day cohort. The patients with RCC in this study remained on treatment the l ongest with m edia...

Ngày tải lên : 10/08/2014, 21:23

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Báo cáo y học: "Successfully treated synchronous double malignancy of the breast and esophagus: a case report" pot

... successfully using combined modalities of surgery, chemotherapy and radiation therapy. Conclusion: Cases of synchronous double malignancies can be treated by dealing with the malignancy in the two ... cur- rently symptom-free and doing well one year and eight months after completion of the treatment. She had fol- low-up clinical examination monthly for one year. An upper...

Ngày tải lên : 11/08/2014, 12:20

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Báo cáo khoa học: Broad antibiotic resistance proﬁle of the subclass B3 metallo-b-lactamase GOB-1, a di-zinc enzyme potx

... zinc ions (Tables 1, 2). Determination of the zinc and iron contents using ICP ⁄ MS In contrast to the wild-type and Q116H enzymes, ICP ⁄ MS failed to highlight the binding of two zinc ions by ... Therefore, the mutation of the glutamine residue at position 116 results in the loss of zinc from the corresponding site of the enzyme under MS conditions. Q116H, l...

Ngày tải lên : 14/03/2014, 23:20

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Báo cáo Y học: ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1 pot

... coordinated interaction of the N-terminus of MDM2 with the N-terminus of p53, and an interaction of the acid domain of MDM2 with the central domain of p53 [24]. Accordingly, ligands such as the ... MDM2 play a mechanistic role in binding to E2F1 and alter- ing its function in a DNA-binding assay. To ensure that the inhibition of E2F1 DNA-binding function...

Ngày tải lên : 24/03/2014, 00:21

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Báo cáo Y học: Novel regulatory regions found downstream of the rat B29/Ig-b gene docx

... to the N -terminal r egion of the cytoplasmic domain. K inases in the Src family, such as Lyn phosphorylate tyrosine residues in ITAM and phosphorylated ITAM, recruit Syk via the SH2 domain to initiate ... greater enhancing activity resulted compared with the activity of the SV-40 promoter alone. The region containing +4.4a to +4.6b showed twice the activity of th...

Ngày tải lên : 24/03/2014, 03:21

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