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Báo cáo y học: "Considerations for the inclusion of 2x mammalian genomes in phylogenetic analyses" ppsx

Báo cáo y học:

Báo cáo y học: "Considerations for the inclusion of 2x mammalian genomes in phylogenetic analyses" ppsx

... evolutionary time for all lineages (blue lines) in the latest Ensembl version (version 59). The red line indicates the lineage leading to the human genome. The dashed part of the line indicates the ... Considerations for the inclusion of 2x mammalian genomes in phylogenetic analyses. Genome Biology 2011, 12:401.Vilella et al. Genome Biology 2011, 12:401 http://genomebiology.com/2011/12/2/401Page 4 of ... mammal genomes in the gene trees increases the probability of finding a gene misplaced in the tree.’ We had anticipated that possibility in our study (page 6, second paragraph in Milinkovitch...
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Báo cáo y học: "Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study" ppt

... the study was approved by the Ethics Committee of Hôpital Kremlin-Bicêtre (Paris,France).GenotypingAll samples were genotyped using the TaqMan allelic dis-crimination assay according to the ... detected. The genotyping success rate in the 434 triofamilies was 100% (parents and probands included).Statistical analysisUsing the previously reported frequencies for the rs6822844-T allele in ... to the rheumatologist in charge of the patient. Each family con-sisted of one RA patient and both parents, with the ethnic-ity as determined by grandparental origin.Characteristics of the...
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Báo cáo y học: " support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation" pot

... 15% of gene order conservation [19], as reuse of linkagebreakpoints is influenced by the fragility of certain types of sequence (see, for example, [51,52]). We start byexamin ing the role of ... irs specifying proteinswith network proximity only remain linked in Kluyvero-myces lactis when recombination between the loci isunusually low [36].We therefore ask whether recombination is ... functionallycoordinated and any appearance to the contrary isowing to tandem duplicates. Equally, we find no evi-dence that the presence of duplicates, using the cutoffdefined by Spellman and Rubin...
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Báo cáo y học: " Factors predicting the outcome of customised foot orthoses in patients with rheumatoid arthritis: a prospective cohort stud" pps

... baseline (before the start of the inter-vention) and at final follow up ( directly after the end of the intervention period). The intervention period consisted of one or more appointments with the ... activity. We concluded a rather stable disease dur-ing the intervention period since minimal changes in medication were recorded in the study population.Therefore, the improvements in pain and ... experience.Potential clinica l predictors related to the foot includethepresenceandseverityofdiseaseactivityinthefootjoints, the pres ence and severity of structural foot defor-mities and the magnitude of pressure...
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Báo cáo y học: "Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary"

... pregnancies are frequently terminated if the fetus is severely affected. Thus, the rate of defects is calculated for informative offspring including (i) live born infants, (ii) stillborn fetuses, ... spectrum of congenital abnormalities evaluated, the period of study (only at birth or in early neonatal period or prenatal or the whole infant period are included), the completeness of ascertainment, ... per 1000 informative offspring in the 1980s and within this, the total rate of major congenital abnormalities was 27.01 per 1000 informative offspring [1,2]. The causes of congenital abnormalities...
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báo cáo hóa học: " Considerations for the future development of virtual technology as a rehabilitation tool" doc

... combination results in 6 DOF for the location information (InterSense, Inc). Other systems usecameras to track the person and then transform this infor-mation to the 6-DOF needed to maintain ... Owned NetworksFrustrated by the lack of QoS on the Internet, there isgrowing interest in bypassing the traditional routed Inter-net by using the available dark fiber in the ground. Darkfiber ... and the location of the sensor within the magnetic field is detected. When the sensor is place on the head or glasses of the person the ori-entation of the head and therefore the location of the...
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Báo cáo y học: "Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling" ppsx

... effects of diac-erein/rhein on the synthesis of major proteases involved in bone remodelling/resorption, namely MMP-13 and cathepsinK. Moreover, we sought to gain new insight into the effects of the ... μg/mL).Effect of diacerein/rhein on intracellular signalling pathwaysTo gain insight into the mechanisms of these drugs on the OAsubchondral bone osteoblasts, we further studied the effect of the therapeutic ... has rhein as itsactive metabolite. In chondrocytes, this drug acts on the IL-1βsystem, reducing the level of this cytokine as well as downreg-ulating the IL-1β-induced inflammatory pathways and...
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Báo cáo y học: "GWASs and the age of human as the model organism for autoimmune genetic research" doc

... matory disease that destroys free moving joints. T1D is a form of diabetes that results from the destruc-tion of insulin-producing beta cells of the pancreas. IBD is a group of in ammatory conditions ... conditions of the colon and small intestine; the two major types are Crohn’s disease and ulcerative colitis. In SLE, the immune system attacks a wide variety of organs, including the heart, joints, ... skin, lungs, blood vessels, liver, kidneys and nervous system. MS is an autoimmune disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are damaged, leading...
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Báo cáo y học: "Barriers to the implementation of programs for the prevention of mother-to-child transmission of HIV: A cross-sectional survey in rural and urban Uganda" pptx

... mother's decision to test for HIV was the strongest predictor of whether the motherhad the intention of testing or not. This finding highlights the importance of the male partner in the ... thought that their husbands would accept the HIVtest for themselves. The analysis shows that the rural and urban mothers wereequally likely to inform their husbands that they hadcome to the antenatal ... clinic that day (Chi square p =0.18). There was no significant difference in the propor-tion of mothers who thought they should consult theirhusbands before they were tested for HIV in the...
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Báo cáo y học:

Báo cáo y học: "Protocol for the Foot in Juvenile Idiopathic Arthritis trial (FiJIA): a randomised controlled trial of an integrated foot care programme for foot problems in JIA" pdf

... thickening1- minimal synovial thickening (filling the angle between adjacent bones without bulging over the line linking the tops of the bones)2- synovial thickening bulging over the line of the ... programme in the management of footproblems in JIA patients. The secondary aim of the studywill be to determine what the optimum timing for inter-vention is in these patients by comparing the outcomes ... beadministered at baseline, then 6 (by post) and 12 monthsfrom baseline. The exploratory nature of the trial will per-mit in- depth examination of the suitability of the JAFI asa primary outcome...
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