Báo cáo y học: "omparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi" pps

... dermatophyte genomes encode the basic meta- bolic machinery for glycolysis, tricarboxylic acid cycle, glyoxylate cycle, pentose phosphate shunt, and synthesis of all 20 standard a mino acids and the ... Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi. Genome Biology 2011 12:R7. Submit your next manuscript to BioM...

Ngày tải lên: 09/08/2014, 22:23

... deglycosylated and untreated smelt AFP displayed similar faceted ice crystal morphology (Fig. 2). The antifreeze activity of the untreat- ed and d eglycosylated samples, quantitate d as thermal hysteresis, ... protein presence and to detect bands not stained by the ruthenium red dye. Analysis of antifreeze activity Antifreeze activity was quantitated a s thermal hysteresis, wh...

Ngày tải lên: 24/03/2014, 03:21

... cells into and within the synovial tissue. The partial overlap of CCL21 and CCR7 expression in the inflamed synovium might suggest that the CCR7/CCL21 system, probably in synergy with CXCR3 and ... chemo- taxis of the latter cells to the ligands of these receptors, and the distribution of cells positive for CCR7, CCR5 and CXCR3 in the inflamed synovium. Met...

Ngày tải lên: 09/08/2014, 06:22

... All the patients had a diagnosis of RA and fulfilled the revised criteria of the American College of Rheumatology [13]. The study was approved by the Ethics Committee of Sahlgren- ska University ... joint diseases and critical revision of the manuscript. AT contributed to the con- ception of the study and study design, statistical evaluation of the result...

Ngày tải lên: 09/08/2014, 06:23

... complete absence of symp- toms in the feet, which are not included in the calculation of the DAS28. These differences are more important [22] than the calculation of other cutoff values for the DAS28 ... remission, low inflammatory activity, no pain, or a high functional capacity [7]. From the perspective of the patient, absence of pain and func- tional ability are...

Ngày tải lên: 09/08/2014, 07:20

... the paucity of the latter cells in SF. In adulthood, transitional B cells generated in the bone marrow are released into the bloodstream and transported to the spleen, where they develop into long-lived ... analysis of B7-1 and B7-2 costimulatory ligands: expres- sion and function. J Exp Med 1994, 180:631-640. 40. Liu YJ, Barthelemy C, de Bouteiller O, Arpin C, Durand...

Ngày tải lên: 09/08/2014, 14:22

... occupancy domains (EPODs) with lengths ranging from 1 to 14 kbp (Figure 1). They then determined the transcrip- tional profiles of the EPODs by DNA microarray analysis and found that they fell into ... maximum of 20 monomers per cell [12]. These obser- vations, together with knowledge of the hierarchy of regulatory networks, have led to the hypothesis of ‘analog’ and...

Ngày tải lên: 09/08/2014, 20:21

... amino acids and there are three isoforms, apoE2, apoE3, and apoE4, encoded by the ε2, ε3, and ε4 genes, respectively. These isoforms differ from each other only at residues 112 and 158 i.e. Cys112 and Arg158 ... follows: y yye e obs NU GmGdnCl RT G HO NU NU HO N = +• + − − [] ⎛ ⎝ ⎜ ⎜ ⎞ ⎠ ⎟ ⎟ − → → → Δ Δ () () 2 2 1 UU NU mGdnCl RT − [] ⎛ ⎝ ⎜ ⎜ ⎞ ⎠ ⎟ ⎟ → (1) where y obs is the...

Ngày tải lên: 10/08/2014, 05:21

... 94%. Thus RRE region is one of the most conserved reg ions in the genomic RNA between HIV-1 subtypes B and C and with probably other subtypes as well. The analysis ofintra-subtypedivergence(geneticdistancefrom Indian ... p C and D as in the case of S1 and VT1. Remarkably, gross changes (particularly D and Sharma et al. AIDS Research and Therapy 2010, 7:28 http://www.ai...

Ngày tải lên: 10/08/2014, 05:21

... methyl groups are always introduced, one slowly by Dnmt3a or by de novo methylation catalyzed by Dnmt1 and the second one very fast. Therefore, this effect can only double the rate of DNA methylation, ... mainten- ance of the methylation at certain DNA sequences. A role of Fig. 3. Stimulation of Dnmt1 and Dnmt3a by fully methylated CpG sites. In this experiment the rates...

Ngày tải lên: 21/02/2014, 01:21