Báo cáo y học: " Strong functional patterns in the evolution of eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoi" doc

... and Godzik: Strong functional patterns in the evolution of eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoires. Genome Biology 2011 12:R4. Submit your next ... 12:R4 http://genomebiology.com/2011/12/1/R4 Page 5 of 13 RESEARCH Open Access Strong functional patterns in the evolution of eukaryotic genomes...

Ngày tải lên: 09/08/2014, 22:23

... for 15 min in the waiting room before MRI scan, but we did not record the intensity of load force and recovery time after running, walking, or sitting. This may influence the measurement of cartilage ... lat- eral edges of the tibial femoral joint space, not including the osteophytes, was evaluated at baseline and at 2 years by two observers for the anterior, body, and p...

Ngày tải lên: 09/08/2014, 10:20

... of the study, in the interpretation of the data and in the revision of manuscript. AA participated in the design and coordination of the study, in the interpreta- tion of the data and in the ... Foundation and the 80-Year Fund of King Gustav V (AS), by the Medical Faculty of the University of Lund (DW), by the Swedish Rheumatism Associa...

Ngày tải lên: 09/08/2014, 10:20

... antibody synthesis to the pathogenesis of RA, their applicability in interventional biopsy-based clinical tri- als is limited. Synovial tissues obtained by arthroscopy or nee- dle biopsy typically ... 1a), sug- gesting that there were no intrinsic differences in antibody detectability between the two types of synovia. The large vari- ability observed in autoantibody concentr...

Ngày tải lên: 09/08/2014, 13:21

... ethno-linguistically more closely related to groups living in other areas. The Kry are hypothe- sized to be the earliest of the current inhabitants. The Kry were followed by the Saek arriving some ... washing the neonate. Medicinal plants are collected either by the husband in the vicinity of the hut, or supplied by relatives if collected from further away. Th...

Ngày tải lên: 10/08/2014, 09:21

... epitopes of gp130 are involved in ligand binding: the Ig-like domain and the CBM [9–11]. In the case of LIF-induced heterodimerization of LIFR with gp130, the cytokine first binds to the Ig-like domain ... membrane-proximal domains of gp130 is limited to ensure the correct spacing between the CBM and the membrane, each of the domains was replaced by the...

Ngày tải lên: 18/03/2014, 01:20

... in the synovium [10]. The lining layer consists mainly of fibroblasts and macrophages, both important players in the process of inflammation by the production of cytokines and degrading enzymes. ... latter finding is in accordance with the study by Lai and co-workers showing that LPS induction of MMP9 in monocytes is mainly regu- lated by the ERK1/2 pathway a...

Ngày tải lên: 09/08/2014, 01:23

... – by the low affinity genotype of FcγRs – of the bypass between immune complex and FcγR bearing cells. In a GPI immunized mouse model severe arthritis occurred only in DBA/1 mice, although the ... regulated by some genes, especially by FcγR genotype, as well as by production of arthritogenic autoantibodies. Competing interests The author(s) declare that they have no...

Ngày tải lên: 09/08/2014, 07:20

... effects of genetic variants on methylation variation and correspondingly the majority of methylation sites assayed across all studies remains unexplained by the GWAS analyses. Howev er, the findings ... mechanisms in a fraction of genes. However, in the re-analyses of the eQTL data taking into account DNA methylation, in only 10% of eQTLs was the gene tic effect...

Ngày tải lên: 09/08/2014, 22:23

... healthy and strong muscle which is adapted to the functional demand may result in a successfully reani- mated major limb function. The reinnervation quality of the donor nerve could be followed by ... (collat- eral of the anterior interosseous artery, one or two super- ficial veins, the sural nerve graft end, and the deep finger flexors bundled together by side-to-si...

Ngày tải lên: 10/08/2014, 10:20