Báo cáo y học: " Strong functional patterns in the evolution of eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoi" doc
Báo cáo y học: " Strong functional patterns in the evolution of eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoi" doc
... and Godzik: Strong functional patterns in the evolution of eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoires. Genome Biology 2011 12:R4.Submit your next ... 12:R4http://genomebiology.com/2011/12/1/R4Page 5 of 13RESEARCH Open Access Strong functional patterns in the evolution of eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoiresChristian M Zmasek, ... detected in any of the analyzed genomes nor as yet unidentifieddomains. Since the Pfam database does not yet cover the complete protein domain universe (especially so fordomains specific to poorly...
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Báo cáo y học: "Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume" pps
... for 15 min in the waiting room before MRI scan, but we did not record the intensity of load force and recovery time after running, walking,or sitting. This may influence the measurement of cartilage ... lat-eral edges of the tibial femoral joint space, not including the osteophytes, was evaluated at baseline and at 2 years by twoobservers for the anterior, body, and posterior horns of the menisci. ... on a section by section basis. These data were then resa-mpled by means of bilinear and cubic interpolation (area of 312 × 312 μm by 1.5 mm thickness, continuous sections) for the final three-dimensional...
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Báo cáo y học: "Serum IL-15 in patients with early systemic sclerosis: a potential novel marker of lung disease" potx
... of the study, in the interpretation of the data and in the revision of manuscript. AA participated in the design and coordination of the study, in the interpreta-tion of the data and in the ... Foundation and the 80-Year Fund of King Gustav V (AS), by the Medical Faculty of the University of Lund (DW), by the Swedish Rheumatism Association (AS), and by the Swed-ish Society of Medicine (DW).References1. ... correlated inversely with the systolic blood pressure by multiple linear regression analysis including variables that mayinfluence the systolic blood pressure (Table 3). Age and the body mass index...
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Báo cáo y học: "Elevated autoantibody content in rheumatoid arthritis synovia with lymphoid aggregates and the effect of rituximab" ppt
... antibody synthesis to the pathogenesis of RA, their applicability in interventional biopsy-based clinical tri-als is limited. Synovial tissues obtained by arthroscopy or nee-dle biopsy typically ... 1a), sug-gesting that there were no intrinsic differences in antibodydetectability between the two types of synovia. The large vari-ability observed in autoantibody concentrations in RA extractsmight ... order to minimize the effects of synovial hetero-geneity [18]. For a given autoantibody or immunoglobulin ana-lyte, synovial/serum index (SSI) was defined as the ratio of synovial analyte/synovial...
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Báo cáo y học: "Traditions and plant use during pregnancy, childbirth and postpartum recovery by the Kry ethnic group in Lao PDr" potx
... ethno-linguistically more closely relatedto groups living in other areas. The Kry are hypothe-sized to be the earliest of the current inhabitants. The Kry were followed by the Saek arriving some ... washing the neonate. Medicinal plants arecollected either by the husband in the vicinity of the hut, or supplied by relatives if collected from furtheraway. The mother is not allowed to bathe ... andremaining there for a period of 3 - 5 days can be viewedas a viability test of mother and infant, and in the case of the Kry the child is not given a name until they havemoved to the main house.The...
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Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot
... epitopes of gp130 areinvolved in ligand binding: the Ig-like domain and the CBM[9–11]. In the case of LIF-induced heterodimerization of LIFR with gp130, the cytokine first binds to the Ig-like domain ... membrane-proximaldomains of gp130 is limited to ensure the correct spacingbetween the CBM and the membrane, each of the domainswas replaced by the corresponding domain of the GCSFR. The replacement ... replaced by the STAT1 recruiting motif of the interferon-c receptor result-ing in a chimeric protein designated gp130c.Inordertoinvestigate the role of the membrane-proximal domains of gp130 in receptor...
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Báo cáo y học: "Strong inhibition of TNF-α production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor" ppt
... in the synovium[10]. The lining layer consists mainly of fibroblasts andmacrophages, both important players in the process of inflammation by the production of cytokines and degradingenzymes. ... latter finding is in accordance with the study by Lai and co-workers showingthat LPS induction of MMP9 in monocytes is mainly regu-lated by the ERK1/2 pathway and not the p38 MAPK path-way [27].p38 ... activated in macrophages in response to a variety of stimuli both in pri-mary cells and in cell lines [9]. In the RA synovium, p38MAPK is predominantly activated in endothelial cells and in the lining...
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Báo cáo y học: "A functional variant of Fcγ receptor IIIA is associated with rheumatoid arthritis in individuals who are positive for anti-glucose-6-phosphate isomerase antibodies" doc
... – by the lowaffinity genotype of FcγRs – of the bypass between immunecomplex and FcγR bearing cells. In a GPI immunized mousemodel severe arthritis occurred only in DBA/1 mice, although the ... regulated by somegenes, especially by FcγR genotype, as well as by production of arthritogenic autoantibodies.Competing interests The author(s) declare that they have no competing interests.Authors' ... participated in the full design andcoordination of the study, and DG, SI and AT participated in writing the discussion.AcknowledgementsThis work was supported in part by the Japanese Ministry of Science...
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Báo cáo y học: " DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines" ppt
... effects of genetic variants on methylationvariation and correspondingly the majority of methylationsites assayed across all studies remains unexplained by the GWAS analyses. Howev er, the findings ... mechanisms in a fraction of genes.However, in the re-analyses of the eQTL data takinginto account DNA methylation, in only 10% of eQTLswas the gene tic effect of the SNP on expression affected by controlling ... RNAsequencing [23,24], as well a s smaller studies of varia-tion in chromatin accessibility and PolII binding [25,26].Finally, one of the HapMap cell lines is now beingintensely studied by the ENCODE...
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Báo cáo y học: "Free functional gracilis muscle transfer in children with severe sequelae from obstetric brachial plexus palsy" potx
... healthy and strong muscle which is adapted to the functional demand may result in a successfully reani-mated major limb function. The reinnervation quality of the donor nerve could be followed by ... (collat-eral of the anterior interosseous artery, one or two super-ficial veins, the sural nerve graft end, and the deep fingerflexors bundled together by side-to-side sutures in an har-monic finger ... biopsy is performed at the proximal forearm level and sent for neuropathologicalexamination. Slices are examined to determinate the pro-portion and quantity of myelinated fibers.If the biopsy...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinChuong 2 nhận dạng rui roTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)Chiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015