... A scalable, fully automated process for construction of sequence-ready barcoded libraries for 454 Genome Biology 2010, 11:R15 Lennon et al. Genome Biology 2010, 11:R15 http://genomebiology.com/2010/11/2/R15 Page ... any automation. Settings used for plate-based shearing of DNA are: Duty Cycle of 5; Intensity of 5; Cycle per Burst of 500; Seconds of 120; Well Pla...
Ngày tải lên: 09/08/2014, 20:21
Báo cáo y học: "A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries" pot
... article as: Fisher et al.: A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries. Genome Biology 2011 12:R1. Submit your next manuscript to ... 15 METH O D Open Access A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries Sheila Fisher...
Ngày tải lên: 09/08/2014, 22:23
... N-(2-Aminopropyl)-4-(6-(pyrimidine-2-yl)-1,2,4,5-tetrazine-3-yl)be nzamide 4 4-(6-(Pyrimidine-2-yl)-1,4-dihydro-1,2,4,5-tetrazi ne-3-yl)benzoic acid (3) was prepared from 2-cyanopyrimidine 1 a nd 4 -cyano-ben ... standardized plan of treatment for every single patient and all available therapy options should be used, such as immunothe- rapy, surgery or chemotherapy sensibly using cyto...
Ngày tải lên: 25/10/2012, 11:40
Báo cáo khoa học: "A Scalable Probabilistic Classifier for Language Modeling" pdf
... inter- polated form of Kneser-Ney smoothing (Kneser and Ney, 1995) was shown to consistently outperform a variety of other smoothing techniques (Chen and Goodman, 1999) and currently constitutes a state- of- the-art 3 generative ... (LR) Yesterday at the press conference Table 2: Feature types and examples for a model of order N=4 and for the context Yesterday at the press conferen...
Ngày tải lên: 07/03/2014, 22:20
Báo cáo y học: "A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia" pps
... Details 1 Department of Psychiatry, Chiba University Hospital, Chiba, Japan, 2 Department of Mental Health, Teikyo University Chiba Medical Center, Chiba, Japan, 3 Department of Psychiatry, Chiba University ... by the Department of Pharmacy of Chiba University Hospital. Clinical variables and cognition The Positive and Negative Syndrome Scale (PANSS) was used to quantify the seve...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "A 64-week, multicenter, open-label study of aripiprazole effectiveness in the management of patients with schizophrenia or schizoaffective disorder in a general psychiatric outpatient setting" pptx
... efficacy and safety of aripiprazole 10, 15 or 20 mg/day for the treatment of patients with acute exacerbations of schizophrenia. J Psychiatr Res 2007, 41(11):895-905. 15. Cutler A, Marcus R, Hardy ... incidence of extrapyramidal symp- toms and hyperprolactinaemia, both side effects that are commonly associated w ith typical antipsychotic agents [3]. Aripiprazole is a novel atypical...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "A cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritis" pps
... the pre- vious study employed fibroblasts derived from an embryo. The previous study examined cell migration by wounding of a con- fluent monolayer of cells, whereas our study examined specific directed ... models for assay of rheumatoid synoviocyte chemotaxis. Clin Exp Rheumatol 1994, 12:293-299. 28. al-Mughales J, Blyth TH, Hunter JA, Wilkinson PC: The chemoat- tractant activity of...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "A novel approach to measure the contribution of matrix metalloproteinase in the overall net proteolytic activity present in synovial fluids of patients with arthritis" pptx
... by zymography The gelatinase activity of SF was determined as previously described [15]. The gelatinolytic activity was measured in arbi- trary units by quantitative analysis of a negatively ... stoichiometric binding of protease inhibitors to the catalytic site of the activated forms of the enzymes. In the present work, we have measured by flow cytometry the net proteolytic activit...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee" potx
... entire study period Exclusion History of underlying inflammatory arthropathy or severe rheumatoid arthritis Hyperuricaemia (>440 μmol/l) and/or past history of gout Recent injury in the area ... analysis were performed to evaluate the safety of 5-Loxin ® in OA patients. Results Seventy patients completed the study. At the end of the study, both doses of 5-Loxin ® conferred clin...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: " A global survey identifies novel upstream components of the Ath5 neurogenic network" pdf
... far relied on binding assays such as yeast-one-hybrid assays [37]. Yeast-one-hybrid assays have been used to identify protein- DNA interactions based on the activity of a DNA-binding pro- tein ... subdomains of the eye. To assess the relevance of the findings in the context of an embryo, we carried out functional assays in vivo and found that 9 out of 12 genes tested by clonal analy...
Ngày tải lên: 09/08/2014, 20:20