Báo cáo y học: " Detecting sequence polymorphisms associated with meiotic recombination hotspots in the human genome" pptx
Báo cáo y học: " Detecting sequence polymorphisms associated with meiotic recombination hotspots in the human genome" pptx
... since the 13-mer motif occurs in only about 40% of human hotspots [32] and the variation in the zinc finger arrayof the Prdm9 gene can expl ain only about 18% of varia-tion in human recombination ... analysiscould not find any local polymorphisms associated with the variation i n crossover rate in hotspots MSTM1a andMSTM1b on human chromosome 1 [45]. Since the two hotspots are within 2 ... formation.Chowdhury et al. [34] identified six genetic loci asso-ciated with recombination phenotype, including one in the RNF212 gene, and also found differences in sequence polymorphisms associated with...
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Báo cáo y học: " Contrasting chromatin organization of CpG islands and exons in the human genome" pot
... CpG density) may prevent nucleosome assembly,considering the active chromatin structure of CGIs in vivo [17].Expectedly, the in vivo nucleosome occupancy within the CGI is remarkably low compared ... website [30]. DNA methylation in human Tcells was mapped to the human genome by using methyl-CpG-binding domain (MBD) proteins and Solexasequencing technology [31]. These data are available ... number of intact cytosines and the totalnumber of intact and bisulfite-converted cytosines wascalculated for each locus to indicate the degree of methy-lation. The cytosines in the CG context...
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Báo cáo y học: "Serum cholesterol concentration associated with aspirin esterase activity in older people: preliminary data"
... two distinct aspirin hydrolysis pathways act: a spontaneous pH-dependent hydrolysis and an en-zymatic hydrolysis by plasma/serum and erythrocyte esterases (6). The circulating aspirin esterase ... are mainly due to butyrylcholinesterase (BChE, pseudocholinesterase) and, in part, to albumin (6). Because of higher aspirin esterase activity lead-ing to faster aspirin hydrolysis, the same ... enzymatically determined. Serum aspirin esterase activity was measured kinetically by a modification (optimized in our laboratory) of the procedure described initially by Sorensen (9). The...
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Báo cáo y học: "Preoperative statin is associated with decreased operative mortality in high risk coronary artery bypass patients" pot
... assessment.DiscussionStatins are one of the most effective medicines intro-duced in the past 25 years. Nonetheless they are stillrelatively under prescribed, especially in patients withoutsymptomatic or obvious ather ... fpatients in both the statin and non-statin treatedgroups. Patients were considered t o be in the “ statin”group if they were taking statins at the time of admis-sion or they were started during the ... statin therapy maintained.Statin use in the current study averaged 42% (range 38- 46%) over the five-year period of 2000-2004. The rela-tively low prevalence may represent a referral bias in that...
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Báo cáo y học: "Differential binding of chemokines to macrophages and neutrophils in the human inflamed synovium" pps
... with thickening of the lining layer(or intima) and infiltration of the sublining layer, mainly bymacrophages and lymphocytes [1]. In addition, the fluid-filled joint cavity contains numerous ... CXCL8 binding. The chemokine binding sites described on phagocytes may beinvolved in the migration of these cells into the inflamed joint.Keywords: chemokines, inflamed, receptors, synoviumReceived: ... [8]. Therefore the ligands for the binding sites described here occur endogenously within the RA joint, adding further evidence towards a role forthese receptors in vivo. In the RA joint the synovialmacrophage...
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Báo cáo y học: "Opitz trigonocephaly syndrome presenting with sudden unexplained death in the operating room: a case report" docx
... multiple c raniosynostectomies but she didwell at the University and was also able to play the piano.Our patient had many of the clinical and anatomicfindings typical of OTCS: the dysmorphic face, ... described by Lalatta [4] and byAzimi [5], cerebral hemorrhage [3] and hearing loss asreportedbyNacarkucuketal.[6]andZampinoetal.[7].We did not find any genetic abnormality either in the karyotype ... I,Kanaya F, Kubota Y, Oike Y, Yamamoto T, Kurosawa K, Fukushima Y, Bohring A, Opitz JM, Yoshiura K, Niikawa N, Naritomi K: Mutations in CD96,a Member of the Immunoglobulin Superfamily, Cause...
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Báo cáo y học: "Rheumatoid cachexia is associated with dyslipidemia and low levels of atheroprotective natural antibodies against phosphorylcholine but not with dietary fat in patients with rheumatoid arthritis: a cross-sectional study" pdf
... points to inflammation in RA being associ-ated with a worsening of the lipid profile [4,5], a factor alreadypresent early in the disease [6]. Dyslipidemia in RA is mainlypresented by low concentrations ... [24-27]. The purpose of this study was to analyze if the type of diet over the previous year, determined by FFQ, was associated with body composition derangement and dyslipidemia in patients with ... tried dietary manipulation in an attempt torelieve symptoms [49,50]. The present finding that dietaryintake of SFAs was significantly associated with disease activ-ity focuses on the immunosuppressive...
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Báo cáo y học: " Detecting DNA regulatory motifs by incorporating positional trends in information content" pdf
... that by increasing the number of starting points, the performance of the method improves. In the light of theseresults, the number of starting points is selected to be verylarge. We then explore ... listed in Table 1. The number of starting points in the algorithm was set at 1 or 100. Starting points were selected according to the MEME procedure as described in the text. The entry labeled with ... of the number ofstarting points on the algorithm; and second, the effect of λ on the ability of the algorithm to detect the known binding sites in the data.As previously discussed, we use the...
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Báo cáo y học: " Food assistance is associated with improved body mass index, food security and attendance at clinic in an HIV program in central Haiti: a prospective observational cohort study" docx
... food insecurity. Clin Infect Dis 2009, 49(7):1096-102.3. Campa A, Yang Z, Lai S, et al: HIV-related wasting in HIV-infected drugusers in the era of highly active antiretroviral therapy. Clin Infect ... the original work is properly cited. the final analy sis. Subjects t hat were e ither enrolled in or discontinued from food rations by the clinical teamduring the period of the study were als ... for interview if they were living with HIV, were being assessed by the clinical team for elig-ibility for the food program, were over the age o f 18years and were not pregnant at the time of interview.Combination...
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Báo cáo y học: "A dentigerous cyst associated with bilaterally impacted mandibular canines in a girl: a case report" potx
... plan.IntroductionDentigerous cysts are the most common developmentalodontogenic cysts, accounting for approximately 25% ofall odontogenic cysts of the jaws. They are frequentlynoted as an incidental finding on radiographs ... eosin-stainedsections of the specimen were prepared. The histopatholo-gic sections showed a cyst lined by thin, non-keratinized,stratified squamous epithelium. The cyst wall consisted ofuninflamed ... of the mandibular caninesonce they were exposed. JP performed the incisional biopsy, curettage, andexposure of the mandibular canines. PG performed the histologicalexamination of the biopsy....
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