... cases and therefore the real incidence of Lyme disease is unknown. In Italy, Lyme disease has been subject to mandatory notification since 1990, but there is likely an underestimation of the real ... information on the incidence of zoonoses in this territory. Two hundred and seventy six new cases of ocu- lar inflammatory disease were examined in this Ser- vice...
Ngày tải lên: 03/11/2012, 11:11
... [33], the issue of the partitioning of the glyoxylate cycle in cells grown under fatty acid-medium conditions has hitherto remained open. We showed here that one of the key glyoxylate-cycle enzymes, ... dehydrogenase activity speci®cally involved in the glyoxylate cycle is attributed to the cytosolic isoform Mdh2p [7]. The suggestion of an extra-peroxisomal locatio...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration docx
... cortex and medulla in the rat kidneys after 3 and 5 days of water restriction. We investigated the quantity of HSP60 in the cyto- plasm and mitochondria by immunoblotting. No changes in the quantity ... papilla of rats that were water restricted but the protein was increased in the mitochondria of the rat kidney papilla. We also analysed binding of t...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo y học: "Association of a specific haplotype across the genes MMP1 and MMP3 with radiographic joint destruction in rheumatoid arthritis" ppt
... level, they are activated by similar factors such as interleukin-1 [37], whereas plasmin and trypsin activate the precursors of both proteins [38]. In addition, MMP1 and MMP3 interact at the protein ... with the Ratingen score (P = 0.044). The presence or absence of the SE explained 29% of the variance of the Ratingen score, independently of the location at D...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Biology of recently discovered cytokines: Discerning the pro- and anti-inflammatory properties of interleukin-27" pptx
... regulating the kinetics and intensity of infection induced immunity. Many of the cytokines produced to combat pathogenic challenge are also characteristic of chronic inflammatory disorders. Accordingly, ... [43]. In contrast, T. gondii and T. cruzi are disseminating infections that induce strong innate immune responses and high serum levels of inflammatory cytokines [43]....
Ngày tải lên: 09/08/2014, 01:24
Báo cáo y học: "Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis" potx
... for any cytokine in any organ at any time point. Discussion The present study documents that, in AIA, elevation of IL- 1β in the SM as well as elevations of IL-6 mRNA in SM, inguinal LN, and spleen ... respectively) peaked from 6 hours to day 3 in the spleen. Increases of the corresponding proteins were significant in comparison with day 0 only in the case...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Reliability of computerized image analysis for the evaluation of serial synovial biopsies in randomized controlled trials in rheumatoid arthritis" pps
... evaluation of ST. The major advantage of DIA is standardization of image acquisition and processing, minimizing variance, and the ability to quantify the actual stained area together with staining intensity ... sections were randomly analyzed by computer-assisted image analysis (Fig. 1). For all markers, 18 high-power fields were analyzed. The images of the high-power fi...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis" potx
... in the zygapophyseal joints and restriction of spinal mobility [6,7]. Acute inflammation in the spine associated with AS, as detected by magnetic resonance imaging (MRI), has been described in ... Veys EM: Involvement of the zygapophy- seal joint in ankylosing spondylitis: relation to the bridging syndesmophyte. J Rheumatol 1999, 26:1738-1745. 6. Simkin PA, Downey DJ,...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Lack of association or interactions between the IL-4, IL-4Rα and IL-13 genes, and rheumatoid arthritis" pptx
... measures the amount of destruction by assessing 32 joints, including 16 areas in both hands (eight joints in each hand), eight areas in both wrists (four joints in each wrist) and eight joints ... conceived and designed the study. All authors contrib- uted to the acquisition of the samples or study data. IM per- formed genotyping as well as all data analyses. All...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Influence of Cyclodextrin Complexation with NSAIDs on NSAID/Cold Stress-Induced Gastric Ulceration in Rats"
... The principal mechanism of action of all NSAIDs is the inhibition of the biosynthesis of prostaglandins by blocking the activity (selectively and/ or non-selectively) of two isoforms of cyclooxygenase ... respectively. The corresponding decreases in the case of piroxicam were 89.2 and 80.3%, respectively. In this study, administration of each of the...
Ngày tải lên: 26/10/2012, 08:57