Báo cáo y học: "Rat traps: filling the toolbox for manipulating the rat genome" ppsx

... selected for and expanded. Figure 2. Techniques for manipulating the rat genome. (a) The mutagenicity of N-ethyl-N-nitrosourea (ENU) is the result of the ability to transfer the ethyl group, ... generation. Here we outline the current status, possibilities and application of these techniques in the rat. © 2010 BioMed Central Ltd Rat traps: lling the toolbox...

Ngày tải lên: 09/08/2014, 22:23

... immediately before exposure to the test drugs. Finally, the se cretory ratio at the peak response was measured to assess the concen- tration-response curves. Measurement of the cAMP Concentration Stomachs ... secretion viatheAtypeofGABA A but not GABA B and glycine receptors in the rat stomach. Gastric acid secretion is not only stimulated via the classical known neuronal and...

Ngày tải lên: 10/08/2014, 05:21

... the Atlas of the rat brain. Our data indicate that the MrD is an ideal choice for the study of MOR in the neostriatum in vivo. Conclusions We have for the first time demonstrated the existence ... memory. The pain related neu- rons have been detected exclusiv ely in the marginal division of the neostriatum. Therefore, MOR is likely to play a role in learning and memo...

Ngày tải lên: 10/08/2014, 05:21

Ngày tải lên: 25/10/2012, 10:02

... copy owing to incomplete bowel preparation. The bleeding was controlled by #3-0 Vycryl intracorporeal suture, and the invagination of the diverticulum was performed laparoscopically. The ... com- pared to the small intestine that is formed of the inner circular and outer longitudinal muscle layers. The vasa recta, which supply the mucosa and submucosa of the colon, pe...

Ngày tải lên: 25/10/2012, 10:51

... reduction in the size of the arachnoid cyst but syrinx still remained. Despite this, the symptoms of the patient were obviously improved compared to before surgery. Thus, for the treatment of foramen ... the cyst. The cyst tightly adhered to the cerebrum, pons and cervical spinal cord. The com- partments were then separated and the posterior wall of the cyst was ex...

Ngày tải lên: 25/10/2012, 11:00

... responsible for the extreme virulence of the “1918 type”, and or the conditions necessary to prevent the reappearance of this influenza. Unlike the typical “flu” that strikes the very young, chronically ... is determined by: the efficiency of the hemagglutinin ability to drift; functional ability of the nueraminidase, and the immunity of the host it infects to fi...

Ngày tải lên: 02/11/2012, 11:12

... evi- dent in ophthalmology, dermatology, dentistry and rheumatology [10,11]. Based up on these data the aim of this study was to observe the potential of Esterified Hyaluronic Acid (EHA) as ... of the bone fragments. The Hyaloss® matrix is highly multipurpose, because at room temperature it can form a biode- gradable, biocompatible gel that can be adapted from the operator t...

Ngày tải lên: 03/11/2012, 11:35

... microorganisms is the (2¢)5¢)oligoadenylate synthetase [(2–5)A synthetase] system [11–13]. The (2–5)A synthetase(s) is activated by certain classes of RNA, mainly double-stranded RNA [14]. In vertebrates the ... the (2–5)A pathway is also induced by interferons [15]. The major enzyme in this pathway, the (2–5)A synthetase catalyzes the synthesis of a series of 2¢)5¢- linked olig...

Ngày tải lên: 21/02/2014, 15:20

... been described for both Zygomycetes. In Phycomyces they complement neither the carR nor the carA mutants, and i n Mucor they complement neither the carP nor the carR mutants. They are white, l ... via three enzymatic steps carried out by the enzymes phytoene synthase, phytoene dehydrogenase and lycopene cyclase. The enzyme phytoene dehydrogenase is able to introduce four dehydro...

Ngày tải lên: 22/02/2014, 04:20