Báo cáo y học: "Host transcription in active and latent tuberculosis" ppsx

... including the cynomolgus macaque [5]. In these primates, active and latent disease seem to be overlapping entities rather than clearly distinct syndromes. e ability to measure Mtb burden in ... 7:845-855. 5. Lin PL, Pawar S, Myers A, Pegu A, Fuhrman C, Reinhart TA, Capuano SV, Klein E, Flynn JL: Early events in Mycobacterium tuberculosis infection in cynomolgus macaques. I...

Ngày tải lên: 09/08/2014, 22:23

... skewing of aberrant T cells). SCID with maternal fetal engraftment is diagnosed by identifying lymphocytes of maternal origin, by XX/XY karyotyping if the patient is male or by tissue typing ... require insulin to maintain glycemic control. Thyroiditis also starts early in life and can result in hyper or hypothyroid- ism. Hematological abnormalities are common, includ- ing: autoimmune h...

Ngày tải lên: 08/08/2014, 21:20

... detectable in OA and RA synovial fluids and joint tissues, and is produced in vitro by both the synovium and chondrocytes in response to inflammatory cytokines [36]. MMP-14, produced principally by RA ... gene functions in chondrocytes, thus resulting in joint instability and OA-like pathology. Thus, novel mechanistic insights into the initiation or progression of OA may b...

Ngày tải lên: 09/08/2014, 01:22

... for histology: samples intended for hematoxylin-eosin (HE) staining and alkaline phosphatase-anti-alkaline phosphatase (APAAP) staining were immediately placed in protective freezing medium (Tissue ... of data and revision of the article. JS participated in drafting and revising the article. RHS participated in the concept and design, analysis and interpretation of data, and...

Ngày tải lên: 09/08/2014, 06:23

... to clot and centrifuged for 10 minutes at 800 g to obtain serum. The organs were fixed in 4% formalin before embedding in paraffin, sectioning, and staining with haematoxylin and eosin. Sections ... [35]; in our study, these two proteins were associated with low sal- ivary secretion capacity as well. CD40 and CD40L are expressed on salivary gland epithelial cells and infiltrat...

Ngày tải lên: 09/08/2014, 10:23

... meeting at the Wellcome Trust Conference Centre in Hinxton, UK in July 2009, to jointly address these issues by bringing together for the first time key representatives of the major methods and ... USA) and Ken Wolfe (Smurfit Institute of Genetics, Dublin, Ireland) gave two examples of how augmenting current methods with additional information (protein-protein interaction and...

Ngày tải lên: 09/08/2014, 20:20

... Japanese in Tokyo, Japan (JPT), Yoruba in Ibadan, Nigeria (YRI), Chinese in Metropolitan Denver, CO, USA (CHD), Gujarati Indians in Houston, TX, USA (GIH), Luhya in Webuye, Kenya (LWK), and Toscani in ... population and conti- nental group (Table 1). We also evaluated the haplotype diversity in each group by averaging the haplotype het- erozygosity in ten 10-kb non-overlap...

Ngày tải lên: 09/08/2014, 22:23

... 1992, 20:527-529. 14. Yoshida K, Kim-Mitsuyama S, Wake R, Izumiya Y, Izumi Y, Yukimura T, Ueda M, Yoshiyama M, Iwao H: Excess aldosterone under normal salt diet induces cardiac hypertrophy and infiltration ... was approved by our Institutional Ethical Committee. Model of hypertrophy Hypertensive myocardial hypertrophy was established to 14 animals (originally 2-months of age and weighin...

Ngày tải lên: 10/08/2014, 09:21

... planning interventions and evaluating outcomes. Recent advances in technology, including imaging, represent an opportunity to employ this tech- nique more frequently and advance our understanding in a ... EMG activity during walking in health and diseaseFigure 4 Tibialis posterior EMG activity during walking in health and disease. Tibialis posterior EMG activity during walking...

Ngày tải lên: 10/08/2014, 21:23

... activityFigure 4 var2csa and Pf332 allele-specific transcriptional activity. (a, b) Transcriptional activity was confirmed for both var2csa allele types in HB3 and HB3CSA, and the single allele types ... Pf332. var2csa and Pf332 alleles in P. falciparum genomes and discriminative assay designFigure 1 var2csa and Pf332 alleles in P. falciparum genomes and discriminative as...

Ngày tải lên: 09/08/2014, 20:20