... 7:3,5mgÆmL)1), and dashed lines show the DSC curvesfor peptides CB and CB1 at 20 lM and CB3 at 50 lM in the absence of liposomes. Dotted and thin solid lines represent the thermal curves for CB and CB1 ... suggested that the N-terminal a-helix of CB1 is located on the surface of the lipid bilayers,whereas the C-terminal a-helix of CB1 is embeddedbelow the surface of the lipid bilayers. These conclusionswere ... orientation in membrane multilayers have also beenshown for melittin, alamethicin and magainin [44,45]. In this study, we examined and compared the disruptivemechanisms of the natural peptide (CB) and...