Intraocular Drug DelIvery - part 1 pps

Intraocular Drug DelIvery - part 1 pps

Intraocular Drug DelIvery - part 1 pps

... Probes as Sustained-Release Drug Delivery Systems . . . . 216 Microelectromechanical Systems Drug Delivery Devices . . . . 219 References . . . . 222 PART III: LOCAL DRUG DELIVERY APPROACH TO ... . . 18 1 Pharmacokinetic and Pharmacodynamic Studies . . . . 18 3 Summary and Future Horizons . . . . 18 9 References . . . . 18 9 13 . Transscleral Drug Delivery to the Reti...

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Intraocular Drug DelIvery - part 6 ppsx

Intraocular Drug DelIvery - part 6 ppsx

... mon- key eyes. Exp Eye Res 19 77; 25 :11 3 11 8. 40. Edelhauser HF, Maren TH. Permeability of human cornea and sclera to sulfonamide carbonic anhydrase inhibitors. Arch Ophthalmol 19 88; 10 6 :11 10 11 15. 41. ... Sci 2000; 41: 118 1 11 85. 26. Ambati J, Gragoudas ES, Miller JW, et al. Transscleral delivery of bioactive protein to the choroid and retina. Invest Ophthalmol Vis Sci 2000;...

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Intraocular Drug DelIvery - part 7 pps

Intraocular Drug DelIvery - part 7 pps

... with 4-week follow-up before any retreatment No. with 12 -week follow-up before any retreatment 1 6 10 50, 75, 10 0, 15 0 30 a 22 22 19 b 2 6 10 50, 75, 10 0, 15 0 20 37 28 c 17 d 3 12 10 50, 75, 10 0, 15 0 30 19 19 19 4 6 10 50, ... Clin Invest 19 81; 67 :12 28 12 31. 30. Striph G, Doft B, Rabin B, Johnson B. Retina S antigen-induced uveitis. The efficacy of cyclos...

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Intraocular Drug DelIvery - part 2 ppt

Intraocular Drug DelIvery - part 2 ppt

... Sci 19 98; 39: 212 1– 213 1. 11 4. Seiler MJ, Aramant RB, Bergstrom A. Co-transplantation of embryonic retina and ret- inal pigment epithelial cells to rabbit retina. Curr Eye Res 19 95; 14 :19 9–207. 11 5. ... Ophthalmol 19 80; 89 :13 1 13 6. 13 0. Tano Y, Chandler DB, McCuen BW, Machemer. Glucocorticosteroid inhibition of intraocular proliferation after injury. Am J Ophthalmol 19...

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Intraocular Drug DelIvery - part 3 ppt

Intraocular Drug DelIvery - part 3 ppt

... Ophthalmol 19 93; 11 1 :12 1 12 5. 31. Doft BH, Weiskopf J, Nillson-Ehle I, Wingard L. Amphotericin clearance in vitrecto- mized versus non-vitrectomized eyes. Ophthalmology 19 85; 92 :16 01 16 05. 32. ... oid (anti-inflam matory) or mineralocor ticoid (salt retaining) activity, and was intro duced in 19 85 (56). The formula of anecortave acetate is 4,9 (11 )-pregnadien -1 7 , 2 1- diol-3...

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Intraocular Drug DelIvery - part 4 pptx

Intraocular Drug DelIvery - part 4 pptx

... Source:FromRef .11 . Table 1 Protective Effect of NT-5 01 on Photoreceptors of rcd1 Dogs Animal # Retina area à Photoreceptor ONL p-value ECT-CNTF treated Not treated 14 85 S1 5.5 3.0 S2 5.8 2.7 S3 6.0 4.0 I1 ... Neuropharmacol 19 95; 18 : 515 –532. 14 . Hoane MR, Puri KD, Xu L, et al. Mammalian-cell-produced neurturin (NTN) is more potent than purified escherichia coli-produced NTN. Ex...

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Intraocular Drug DelIvery - part 5 pptx

Intraocular Drug DelIvery - part 5 pptx

... cells, Muller cells (11 15 ) þþþ ( > 3 yr) Humoral Heparin sulfate; a v b5 integrin (16 ) bFGF receptor (17 ) AAV; serotype 5 DNA (single- stranded) 4.8 kb RPE; photorecep- tors (11 ,14 ,18 ) þþþ ( > ... Humoral 2,3-Sialic acid (18 ,19 ) NR AAV; serotype 1 DNA (single- stranded) 4.8 kb RPE cells, cone photorecep- tors (11 ,14 ,18 ) þþþ ( > 3 yr) Humoral NR NR AAV; serotype 4 (2...

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Intraocular Drug DelIvery - part 8 pdf

Intraocular Drug DelIvery - part 8 pdf

... interferon alfa? Arch Ophthalmol 19 92; 11 0 (10 ) :13 83 13 84. 42. Thomas MA, Ibanez HE. Interferon alfa-2a in the treatment of subfoveal choroidal neo- vascularization. Am J Ophthalmol 19 93; 11 5(5):563–568. 43. ... quantita- tion of blood–retinal barrier breakdown in experimental proliferative vitreoretinopathy [erratum appears in Arch Ophthalmol 19 94; 11 2(6):789]. Arch Ophthalmo...

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Intraocular Drug DelIvery - part 9 docx

Intraocular Drug DelIvery - part 9 docx

... Ophthalmol 19 85; 10 3 :17 96 18 06. 9. Klein R, Klein BEK, Moss SE, et al. The Wisconsin Epidemiologic Study of Diabetic Retinopathy. IV. Diabetic macular edema. Ophthalmology 19 84; 91: 1464 14 74. 10 . Early ... J Ophthalmol 19 81; 91: 785–788. 18 . Schindler RH, Chandler DB, Thresher R, Machemer R. The clearance of intravitreal tri- macinolone acetonide. Am J Ophthalmol 19 82; 93:...

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Intraocular Drug DelIvery - part 10 docx

Intraocular Drug DelIvery - part 10 docx

... 74, 10 1, 206, 276 Elimination half-life, 85 Embryo–fetal development study, 63 Encapsulated cell technology (ECT), 11 1, 11 8, 12 9, 15 7, 16 1 Endophthalmitis, 10 , 11 12 , 15 , 48, 332, 3 41 bleb-related, ... 98–99, 10 8 Rhegmatogenous retinal detachments (RRD), 98 Rheologic therapy, 310 blood viscosity, 310 – 311 hemodilution, 311 pharmacologic agents, 310 – 311 Rhodopsin,...

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