Neurology Seminars in Clinical Neurology - part 4 ppsx

... serotypes have been used in the clinic, such as BoNT C and F , with prelim- inary results. Following an intramuscular injection, the toxin dif- fuses in the surr ounding tissue. The size of the ... collect- ed on the use of reserpine, a dopamine-depleting agent, which may have an indication for tardive dysto - nia. A particular type of neuroleptic treatment, which has been used mainly...

Ngày tải lên: 09/08/2014, 20:22

... be of particular value to physicians in developing countries who have lim- ited diagnostic and therapeutic resources. Maintaining this focus is challenging in view of the increasing depend- ence ... Federation of Neurology Seminars in Clinical Neurology Dystonia FACULTY Joseph Jankovic, M.D., CHAIR Professor of Neurology Director of Parkinson’s Disease Center and Movement Diso...

Ngày tải lên: 09/08/2014, 20:22

... Ceroid-lipofuscinosis • Ataxia-telangiectasia • Neuroacanthocytosis • Intraneuronal inclusion disease • Juvenile Parkinsonism (Parkin) • X-linked recessive • Lubag (X-linked dystonia-parkinsonism ... Brin MF, et al. Dystonia gene in Ashkenazi Jewish population is located in chromo- some 9q3 2-3 4. Ann Neurol 1990;27:1 14 120. Lowenstein DH, Aminoff MJ. The clinical course of spasmod...

Ngày tải lên: 09/08/2014, 20:22

... light chain. The for- mer is important in binding to the pr esynaptic neuro- muscular terminals, whereas the latter is released into the terminals. The light chain is a zinc metalloen- dopeptidase, ... T etrabenazine, being predominantly a presynaptic dopamine-deplet- ing agent, may be tried in some patients. Other drugs such as anticonvulsants (carba- mazepine) have been effective in...

Ngày tải lên: 09/08/2014, 20:22

... considered in a short-term fol- low-up. In selected patients, however, DBS could pro- duce a greater benefit (thereby becoming cost-effective). Improvement in self-care and activities of daily living ... albumin; Hemagglutinin; human Hemagglutinin and excipients sodium chloride albumin 20% solution; nonhemagglutinin proteins; lactose human albumin solution 0.05%; sodium chloride; sodi...

Ngày tải lên: 09/08/2014, 20:22

... 52 splinting/bracing, 28, 30 sporadic deafness/dystonia, 3 t Stacy, Mark A. 74, 23 sternocleidomastoid exercise, 44 45 , 44 , 45 , 46 , 46 , 47 48 , 48 , 50, 50 strengthening exercises, 40 , 47 –52 stretching exercises, ... 28, 31 small interfering RNA (siRNA), 41 spasmodic dysphonia, 5 surgical treatment in, 39 spasticity, 2 speech therapy, 40 splenius capitis exercise, 43 44...

Ngày tải lên: 09/08/2014, 20:22

... defensive medicine. This practice involves using tests and therapies with very small marginal returns to preclude future criticism in the event of an adverse outcome. For example, a 40 -year-old woman ... therapy in their heart failure patients because they are more familiar with what the targets are (as defined by large clinical trials), have more familiarity with the specific dr...

Ngày tải lên: 06/07/2014, 08:20

... circulating plasma drug concentration. Clinical Implications of Altered Protein Binding For drugs that are normally highly bound to plasma proteins (>90%), small changes in the extent of binding ... large change in the amount of unbound drug, and hence drug effect. The acute-phase reactant 1 - acid glycoprotein binds to basic drugs, such as lidocaine or quinidine, and is in...

Ngày tải lên: 06/07/2014, 08:20

... that, for the majority of adult-onset, multifactorial genetic Chapter 0 64. The Practice of Genetics in Clinical Medicine (Part 4) Figure 6 4- 2 disorders, testing is purely predictive. Test ... disorder. In addition to molecular testing for established disease, genetic testing for susceptibility to chronic disease is being increasingly integrated into the practice of medic...

Ngày tải lên: 07/07/2014, 01:20