Báo cáo y học: "The past is a foreign country" docx

... Intheirlifetime,noonehaseverpipettedanythingby mouth. • DNAsequencing,peptidesynthesis,chemicalanalysis, and gene synthesis have always been farmed out to specialty companies rather than done ... own lab. • ey have almost certainly never seen anyone blow glass. In fact, many of them may not know that test tubes were ever made of anything but plastic. • ey have...

Ngày tải lên: 09/08/2014, 20:22

... of RNase T1 [23,26,27] and His50 of a- sarcin [20] are involved in catalysis rather than in substrate binding. The role of Arg77 has not yet been established as all attempts to isolate any RNase ... cleavage was observed even when 100 ng of the mutant variants were assayed. In addition, although wild-type a- sarcin degrades polyadenylic acid on a zymo- gram assay, R121K and R121Q did not...

Ngày tải lên: 31/03/2014, 23:20

... Nosocomial Pathogens in Turkey Adalet Altunsoy 1 , Cenk Aypak 2  , Alpay Azap 1 , Önder Ergönül 3 , İsmail Balık 1 1. Department of Clinical Microbiology and Infectious Disease, Ankara University, ... February 2003 by a central regulation of Ministry of Health and was announced nation-wide via official newspaper of the state [11]. This is a quasi-experimental study performed in...

Ngày tải lên: 25/10/2012, 11:00

... directed against P48 and TF, analyzed on SDS/ PAGE and visualized with a PhosphorImager. (B) Quantification of data presented in panel (A) , after correction for translation efficiency. The highest amounts ... The leader peptidase cleavage site is depicted with an arrow. Table 1. Bacterial strains and plasmids used in this study. Ts, temperature sensitive. Cam r and Amp r , resistance to chl...

Ngày tải lên: 08/03/2014, 09:20

... reactivity of a- hydroxyhaem and verdohaem bound to haem oxygenase-1 to dioxygen and sodium dithionite Hiroshi Sakamoto 1 , Yoshiaki Omata 1 , Shunsuke Hayashi 1 , Saori Harada 1 , Graham Palmer 2 and ... can contain a substantial amount of free a- hydroxyhaem and this can lead to an incorrect interpret- ation of the nature of the enzyme-assisted conversion of a- hydroxyhaem to verdohaem...

Ngày tải lên: 23/03/2014, 21:20

... 90) is probably the translational start site because it is followed by a typical signal peptide motif with a basic residue (lysine) and a hydrophobic region (rich in valine and alanine) and matches ... homogeneity by two additional analytical RP/HPLC purification steps as con- firmed by capillary zone electrophoresis (data not shown). MALDI-TOF MS analysis of both fractions revealed t...

Ngày tải lên: 24/03/2014, 03:21

... reported a brief measure of severity for RA based on physician's rating of disease activity, functional impairment, and physical damage. Navarro-Cano and colleagues [25] measured RA disease severity ... study was approved by the Institutional Review Board of Partners HealthCare (Boston, MA, USA). Statistical analysis To test the convergent validity of RARBIS as a measure of dis- ease...

Ngày tải lên: 09/08/2014, 07:20

... convergent validity? The DAS28 is a process measure of disease activity, incorporating clinical status (joint counts and global health) and acute phase reactants [4]. Disease activity is associated ... improve conceptually by such a statistical effort. Only substantial — and not statistical — arguments that favour an increased weight of disease activity (clinical status) in a severi...

Ngày tải lên: 09/08/2014, 07:20

... details about cell surface marker expression and functional characteristics of these cells is unknown, particularly in patients with inflammatory arthritis. In a recent issue of Arthritis, Research ... CD16-, and a small subset considered as non-classical monocytes, which are CD14+ CD16+ [5]. This latter population is increased in the circulation and synovial tissues of rheumatoid art...

Ngày tải lên: 09/08/2014, 14:21

... data acquisition, provided technical assistance and assisted in analysis and interpretation of data. TT, HJ and IA participated in data acquisition. PN performed the statistical analysis and assisted ... Kubo M, Kiyohara Y, Kato I, Iwamoto H, Nakayama K, Hirakata H, Fujishima M: Effect of hyperinsulinemia on renal function in a general Japanese population: the Hisayama study. Kidney Int 19...

Ngày tải lên: 09/08/2014, 14:22