Báo cáo y học: "olutionary divergence in the fungal response to fluconazole revealed by soft clustering" pptx

... relates to the environment: it is very difficult to mirror in the l aboratory the range of conditions that must be experienced by yeast in the wild during the evolution o f stress response pathways. ... 11:R77 http://genomebiology.com/2010/11/7/R77 Page 6 of 12 RESEA R C H Open Access Evolutionary divergence in the fungal response to fluconazole revealed...

Ngày tải lên: 09/08/2014, 20:22

... [57]. Recognizing early symptoms of hepatic toxicity and dis- continuing treatment are important in optimizing recov- ery. Early symptoms of hepatic toxicity include apathy, malaise, fever, diminished ... portacaval shunting, thereby decreasing first pass metabolism; decrease in quantities and affinity of plasma proteins, thereby increasing free-drug levels; increase in volume of distri...

Ngày tải lên: 25/10/2012, 10:51

... located in the vicinity of the translation initiation codon, it may alter translation efficiency. The nearby proximal nucleo- tides to the AUG initiation codon are important for the initiation ... skin tumors at an ex- tremely high frequency (1000 fold increased incidence as compared to normal individuals) because of their inability to repair UV-induced DNA lesions. The...

Ngày tải lên: 31/10/2012, 14:59

... recognized by specific olfactory receptors. The transduction events following binding of the receptor have been recently clarified by the discovery of the first putative invertebrate odorant receptor genes ... whereas by using in situ hybridization to mRNA we revealed only the expressing cells that are likely to be olfactory neurons. The immunological study [23] suggest...

Ngày tải lên: 17/03/2014, 23:20

... mucous-secreting glands; the effectiveness of the mucociliary system is reduced, resulting in symptoms of nasal stuffiness. In addition, a decrease in nasal blood flow leads to atrophy and drying of the ... profuse rhinorrhea elicited by eating food, particularly highly seasoned foods. Cold air may also be a trigger. Anticholinergic drugs may be useful in reducing the rhin...

Ngày tải lên: 08/08/2014, 21:20

... be independent to depression, to general psychopathology symptoms or motor side-effects induced by antipsychotic agents. Regarding the relationship of physical anhedonia and negative symptoms the ... to general psychopathol- ogy symptoms, estimated by both the PANSS and the BPRS. We did not find any studies exploring the the relationship between physical anhedonia and moto...

Ngày tải lên: 08/08/2014, 21:20

... similar responses to IL-1β like native cartilage explants, indicating the relevance of both in vitro systems to study chondrocyte biology on proinflam- matory stimuli [10,73]. For the in vitro analysis ... sources for tissue engineering in rheumatic diseases Today, autologous chondrocytes represent the only cell type routinely used for joint cartilage repair. In the future...

Ngày tải lên: 09/08/2014, 01:22

... joints, and it results in the accumu- lation of leukocytes within the synovial tissue (ST) and synovial fluid (SF). The inflammatory infiltrate consists pre- dominantly of B lymphocytes, T lymphocytes ... recruitment of these cells into the RA synovium, in addition to their positioning and retention within the syno- vial infiltrates. In this regard, the role of CXCR5 on B...

Ngày tải lên: 09/08/2014, 06:22

... monocytes may also be contributing to the pathol- ogy of other inflammatory autoimmune diseases. Such a corollary suggests it may be of interest to investigate mtDNA within other inflammatory autoimmune ... early bacterial infection in the joint. Somatic mutations in mitochondrial peptides displayed by MHCs may be recognized as non-self, furthering the destructive immune infil...

Ngày tải lên: 09/08/2014, 06:23

... interactions appear to significantly increase the risk of new depressive symptoms, even more so than activity losses in other domains [22]. The role of leisure in maintaining or restoring psychological ... well- being in the presence of arthritis pain warrants further study. Psychosocial approaches to managing arthritis pain Search strategy The EBSCOhost platform was used t...

Ngày tải lên: 09/08/2014, 08:23