Báo cáo y học: " Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis" ppt
Báo cáo y học: "Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan" potx
... Ploidy703 of 1,173 tumors were available to examine the status of DNA ploidy using flow cytometry by following the method of Dressler et al.[24].TheDNAindex(DI),representing the ratio of the ... Molecular karyotype profiling of the two subtypes of sporadic CRCs revealed significantdifferences in the extent and distr ibution of CN altera-tions in the cancer genome. Combining the data of gen-ome-wide ... commonly found in CRC MSStumors (8 out o f 13 samples, 62%) according to gen-ome-wide CNA analysis. To replicate the findings from theSNParrayanalysis,weapplied qPCR approach toevaluate the EGFR...
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Báo cáo y học: " Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis" ppt
... reconstruct the most likely tumor line-age and to infer, simultaneously, the copy number profiles of the intermediate nodes. In other words, wewant to reconstruct the copy number profiles of the common ... Biology 2010, 11:R76http://genomebiology.com/2010/11/7/R76Page 9 of 19METH O D Open Access Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive ... parts of the organ, or di fferent parts of the body. Analysis of the copy number profiles of metastases in the data set from the study by Liu et al. [19] revealed the relationshipsbetween the metastases...
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Báo cáo y học: "Analysis of HLA DR, HLA DQ, C4A, FcγRIIa, FcγRIIIa, MBL, and IL-1Ra allelic variants in Caucasian systemic lupus erythematosus patients suggests an effect of the combined FcγRIIa R/R and IL-1Ra 2/2 genotypes on disease susceptibility" pptx
... genes may act in concert in the pathogenesis of SLE, a concept that may beinstrumental in the analysis of the genetics of SLE as wellas providing hypotheses for pathways in the pathogenesis of lupus.Figure ... low number of patients included in the study, the results must be interpreted cautiously, and inde-pendent confirmation is needed.ConclusionOur findings suggest that the combination of the ... polymorphism The genetic polymorphism resulting in amino acid R or H in amino acid position 131 was determined as previouslydescribed [20]. Analysis of FcγRIIIa gene polymorphism The analysis...
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Báo cáo y học: "Analysis of immunoglobulin light chain rearrangements in the salivary gland and blood of a patient with Sjögren’s syndrome" pptx
... 0.005).Further analysis of the distribution of individual Vκ genes in the productive Vκ gene repertoire revealed a significantlyhigher frequency of the gene A27 in the parotid gland of the patient ... is inline with the assumption that plasma and memory B cells accumu-late in the parotid gland but cannot clarify the origin of these cells. Whatever the primary aberration in the induc-tion of ... suggest that inflamed ductal epithelialcells represent the focus of the inflammatory response in the salivary glands of patients with SS. There is clear evi-dence of an inflammatory environment...
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Báo cáo y học: "Analysis of C4 and the C4 binding protein in the MRL/lpr mouse" pptx
... preventing the for-mation of the C3 convertase by binding to C4b; accelerating the natural decay of the classical pathway C3 convertase; andas a cofactor for the serine proteinase factor I in the ... Regula-tion of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding protein. J Immunol2006, 176:7612-7620.22. Webb JH, Blom AM, Dahlback B: The binding of ... chain. Other isoformscontain either seven α chains without a β chain or six α chainswith one β chain. The α chain is composed of eight comple-ment control protein domains, and the N-terminal...
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Báo cáo y học: "Analysis of TNFAIP3, a feedback inhibitor of nuclear factor-κB and the neighbor intergenic 6q23 region in rheumatoid arthritis susceptibility" pot
... participated in the analysis and interpretation of results. AG participated in the design of the study and in the coordination of acquisition of clinical data and collection of samples, and supervised ... role in RA by virtue of the anti-inflammatory effects of its encoded protein. It is involved in many regulatory feedback loops through the cooperativeactivity of its two ubiquitin-editing domains ... partic-ipated in the acquisition of clinical data and collection of sam-ples, and in the analysis and interpretation of results. JJG-Rcoordinated the acquisition of clinical data and collection of samples, ...
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Báo cáo y học: " Analysis on the clinical features of 22 basaloid squamous cell carcinoma of the lung" doc
... pneumonectomy,lobectomy, segmentectomy) has no bearing on the prog-nosis of BC and PDSC patients [8].Differences between the findings in this study andother research may be due to variations in the source of case ... treatment mode and clinicalstage of the tumor. The post-operation mortality hazard of patients treat ed with a combination of chemotherapyand radiotherapy was 1.296 times higher than othertreatment ... carcinoma of the lung was first described in a study conducted byBrambilla in 1992, which analyzed the ultrastructuralfeatures of basaloid carcinoma of the lung [4]. Of the 38cases analyz ed,...
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Báo cáo y học: "Spontaneous Hemoperitoneum Caused By a Diverticulum of the Sigmoid Colon"
... Int. J. Med. Sci. 2011, 8 http://www.medsci.org 468 copy owing to incomplete bowel preparation. The bleeding was controlled by #3-0 Vycryl intracorporeal suture, and the invagination of ... longitudinal muscle layers. The vasa recta, which supply the mucosa and submucosa of the colon, penetrate the circular muscle. The weakness of the vascular portals in the circular muscle possibly ... diverticu-lum [14]. Invagination and diverticulectomy have been performed to treat diverticula to preserve the blood supply to the intestine. In the present case, blood supply to the intestine had to...
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Báo cáo y học: "Foramen Magnum Arachnoid Cyst Induces Compression of the Spinal Cord and Syringomyelia: Case Report and Literature Review"
... arachnoid cyst; syringomyelia. Introduction The commonest type of arachnoid cyst that causes compression of the spinal cord and develop-ment of syringomyelia is the Chiari malformation type I ... herniates into the foramen magnum and spinal canal to com-press the spinal cord, consequently causing blockage of the spinal canal and the stoppage of cerebral spinal flow, leading to syringomyelia ... cyst and tight adhesion to the spinal cord. Three months after the surgery, MRI showed a reduction in the size of the arachnoid cyst but syrinx still remained. Despite this, the symptoms of...
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Báo cáo y học: "Multivariate explanatory model for sporadic carcinoma of the colon in Dukes’ stages I and IIa"
... meva-lonate pathway in patients with SCRC depending on the location of the tumour in the large intestine [31]. The use of LR for the observational studies continues to being authenticated by the bibliography, ... outliers; they were included in the final quality control because they could not be excluded based on the eligibility criteria. A normality study of the quantitative variables in the combined ... controls and 3 cases at the defining moment of the construction of the data package. The funda-mental cause was the lack of fulfilment of the inclu-sion criteria. The assembly of the previous data...
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