Báo cáo y học: " Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis" ppt

... Ploidy 703 of 1,173 tumors were available to examine the status of DNA ploidy using flow cytometry by following the method of Dressler et al.[24].TheDNAindex(DI), representing the ratio of the ... Molecular karyotype profiling of the two subtypes of sporadic CRCs revealed significant differences in the extent and distr ibution of CN altera- tions in the cancer...

Ngày tải lên: 10/08/2014, 05:21

... reconstruct the most likely tumor line- age and to infer, simultaneously, the copy number profiles of the intermediate nodes. In other words, we want to reconstruct the copy number profiles of the common ... Biology 2010, 11:R76 http://genomebiology.com/2010/11/7/R76 Page 9 of 19 METH O D Open Access Analysis of the copy number profiles of severa...

Ngày tải lên: 09/08/2014, 20:22

... genes may act in concert in the pathogenesis of SLE, a concept that may be instrumental in the analysis of the genetics of SLE as well as providing hypotheses for pathways in the pathogenesis of lupus. Figure ... low number of patients included in the study, the results must be interpreted cautiously, and inde- pendent confirmation is needed. Conclusion Our...

Ngày tải lên: 09/08/2014, 01:24

... 0.005). Further analysis of the distribution of individual Vκ genes in the productive Vκ gene repertoire revealed a significantly higher frequency of the gene A27 in the parotid gland of the patient ... is inline with the assumption that plasma and memory B cells accumu- late in the parotid gland but cannot clarify the origin of these cells. Whatever the...

Ngày tải lên: 09/08/2014, 03:24

... preventing the for- mation of the C3 convertase by binding to C4b; accelerating the natural decay of the classical pathway C3 convertase; and as a cofactor for the serine proteinase factor I in the ... Regula- tion of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding protein. J Immunol 2006, 176:7612-7620. 22. Webb JH, B...

Ngày tải lên: 09/08/2014, 10:21

... participated in the analysis and interpretation of results. AG participated in the design of the study and in the coordination of acquisition of clinical data and collection of samples, and supervised ... role in RA by virtue of the anti-inflammatory effects of its encoded protein. It is involved in many regulatory feedback loops through the cooperative...

Ngày tải lên: 09/08/2014, 14:20

... pneumonectomy, lobectomy, segmentectomy) has no bearing on the prog- nosis of BC and PDSC patients [8]. Differences between the findings in this study and other research may be due to variations in the source of case ... treatment mode and clinical stage of the tumor. The post-operation mortality hazard of patients treat ed with a combination of chemotherapy and radio...

Ngày tải lên: 10/08/2014, 09:23

... Int. J. Med. Sci. 2011, 8 http://www.medsci.org 468 copy owing to incomplete bowel preparation. The bleeding was controlled by #3-0 Vycryl intracorporeal suture, and the invagination of ... longitudinal muscle layers. The vasa recta, which supply the mucosa and submucosa of the colon, penetrate the circular muscle. The weakness of the vascular portals in the...

Ngày tải lên: 25/10/2012, 10:51

... arachnoid cyst; syringomyelia. Introduction The commonest type of arachnoid cyst that causes compression of the spinal cord and develop- ment of syringomyelia is the Chiari malformation type I ... herniates into the foramen magnum and spinal canal to com- press the spinal cord, consequently causing blockage of the spinal canal and the stoppage of cerebral spinal f...

Ngày tải lên: 25/10/2012, 11:00

... meva- lonate pathway in patients with SCRC depending on the location of the tumour in the large intestine [31]. The use of LR for the observational studies continues to being authenticated by the bibliography, ... outliers; they were included in the final quality control because they could not be excluded based on the eligibility criteria. A normality study of...

Ngày tải lên: 03/11/2012, 11:34