Báo cáo y học: "RNA polymerase mapping during stress responses reveals widespread nonproductive transcription in yeast" docx

... 13 RESEA R C H Open Access RNA polymerase mapping during stress responses reveals widespread nonproductive transcription in yeast Tae Soo Kim 1 , Chih Long Liu 2,6 , Moran Yassour 3,4 , John Holik 2 , ... polymerases rather than the more evenly spaced polymerases seen at growth/housekeeping genes [24], and it has recently been shown that a trailing polymerase can aid the...

Ngày tải lên: 09/08/2014, 20:22

... different insulin secretagogues, but not glucose, increase intracellular Ca 2+ in fetal rat b cells [36]. H owever, the inability of fetal b cells to release insulin in response to glucose may be ... °C until the insulin assays. Insulin was measured by the radioimmun o- assay method of Herbert et al. [15], using rat insulin as a standa rd. RNA isolation and Northern-blot analysis Total ce...

Ngày tải lên: 31/03/2014, 15:20

... hyaluronidases in synovial fluids are not involved in the direct digestion of hyaluronan in joint fluids, because a neutral pH is maintained in synovial fluids, and so hyaluro- nidase-1 may function only ... approximately four times that in the control synovium. This finding sug- gests that in OA and RA, the protein expression of hyaluronidase-2 in the synovium is increased and...

Ngày tải lên: 09/08/2014, 01:24

... defects in humans [5,6]. However, to date, the delivery of MSCs into cartilaginous lesions has neither clin- ically nor experimentally resulted in sustained regeneration of hyaline cartilage in vivo ... GAG: glycosaminoglycan; GFP: green fluorescent protein; H&E: hematoxylin and eosin; Ig: immunoglobulin; IHH: indian hedgehog; Luc: luciferase; MSC: mesenchymal stem cell; OP: osteop...

Ngày tải lên: 09/08/2014, 14:22

... efficiency in AS silencing. Keywords: argininosuccinate synthetas e arginine deiminase , resistance, RNA interference Background Arginine deiminase depletes arginine by hydrolyzing it to ci trulline. ... Sensitivity of cancer cells to recombinant arginine deiminase (rADI) depends on expression of argininosuccinate synthetase (AS), a rate-limiting enzyme in synthesis of arginine from citru...

Ngày tải lên: 10/08/2014, 05:21

... worsening cardiopulmon- ary parameters, including increased work to breathe, and maintained on epinephrine 0.15 mcg/kg/min, nore- pinephrine 0.1 mcg/kg/min and dobutamine 3 mcg/kg/ min. He was transferr ... timing of emer- gency resternotomy, the number of attempts at defibril- lation before reopening, the administration of epinephrine, and emergency resternotomy sets [1]. How- ever, this gui...

Ngày tải lên: 10/08/2014, 09:21

... Polo-like kinase-1; RISC: RNA-induced silencing complex; RNAi: RNA interference; siRNA: small interfering RNA; TKI: Tyrosine kinase inhibitor Figure 2 Application o f PLK-1 RNAi therapy against liver metastatic ... spindle checkpoint and DNA damage checkpoint, resulting in increased tran- scription of PLK-2 and PLK-3. Consequently, these PLK family kinases cooperatively prevented G2/M trans...

Ngày tải lên: 10/08/2014, 09:22

... E REP O R T Open Access Pulmonary artery injury during mediastinoscopy controlled without gauze packing Muneo Minowa 1 , Masayuki Chida 2* , Syunsuke Eba 3 , Yuji Matsumura 1 Abstract The most ... tomogra- phy (CT) scanning demonstrated #4R and #7 lymphade- nopathy without tumors in the lung field (Figure 1). A gastrointestinal fiberscope examination found no malignancy in the upper gas...

Ngày tải lên: 10/08/2014, 09:23

... as indicative of increased mobility. In addition to providing information regarding foot mobility, the ArchHtWB value also appears to be predic- tive of foot posture during mid-stance in walking ... easily and quickly in the clinic. Another limitation of this study is that it was conducted entirely on asymptomatic individuals. As such, the nor- mal values reported in this study may...

Ngày tải lên: 10/08/2014, 21:23

... acceptance cited in PubMed and archived on PubMed Central yours — you keep the copyright Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp BioMedcentral Journal of Foot and ... the correct corre- sponding email address is kellykaydpt@yahoo.com. References 1. McPoil TG, Cornwall MW, Medoff L, Vicenzion B, Fosberg K, Hilz D: Arch height change during sit-to-...

Ngày tải lên: 10/08/2014, 21:23