Báo cáo y học: "MicroRNA processing without Dicer" docx

... from RNA poly merase II or, rarely, RNA polymerase III promoters, yielding primary transcripts (pri-miRNAs) that are processed by a micro- processor complex containing the RNase III enzyme Drosha. ... the evolutionary conservation of its catalytic activity. In agreement with this, the catalytic activity of Ago2 is also required for zebrafish development and cleavage of miR-451 by Ago2 i...

Ngày tải lên: 09/08/2014, 20:22

... psychiatry 3rd edition. Edited by: Sadavoy J, Jarvik LF, Grossberg GT, Meyers BS. New York: W. W. Norton; 2004:315-370. 33. Khot V, Wyatt RJ: Not all that moves is tardive dyskinesia. Am J Psychiatry ... from other similar syndromes – malig- nant hyperthermia, NMS, toxic serotonin syndrome, stiff- person syndrome, locked-in syndrome, hypocalcemia, tetanus, strychnine toxicity, rabies, and el...

Ngày tải lên: 08/08/2014, 21:20

... regulatory pathways, particularly the NF-κB pathway. Hypoxia, or hypoxia and reoxygenation? Studies of RA synovium in vivo have suggested that synovial perfusion is influenced directly by high ... MK, Kim JS, Park BH, Kim JR, Hwang BY, Lee HY, Song EK, Yoo WH: NF- κκ B-dependent lymphocyte hyperadhesiveness to synovial fibroblasts by hypoxia and reoxygenation: poten- tial role in rheumatoid ....

Ngày tải lên: 09/08/2014, 01:24

... suppressed slightly in AT2V (the OPR is approximately 6) compared with AT1V (the OPR is approximately 5). However, the standard strain of C. albicans increased similarly at any pH and both in ... and other yeasts. 6,9-11 They estimated that the acidic pH and/or the hyperosmolality might sup- press the bacterial growth. 9,10,12 The results of 3 bacte- rial species in this study demonstr...

Ngày tải lên: 26/10/2012, 09:39

... exercise LV dyssynchrony may play a more important role in the pathophysiology of left ven- tricular remodelling than baseline LV dyssynchrony (23). Probably for that reason additional hemodynamic ... mechanical dyssynchrony. These findings may further explain why patients with normal QRS duration may benefit from cardiac re- synchronization whether or not they have mechanical dyssynchro...

Ngày tải lên: 05/11/2012, 11:32

... were synthesized as C-ter- minal amides on a Gilson AMS422 Multiple Peptide Synthesizer using Fmoc chemistry with pentrafluorophenyl amino acid active esters and a polyethylene glycol polysty- rene ... 5-(4¢-Fmoc-aminomethyl-3¢-5¢-dimeth- oxyphenoxy)valeric acid linker. After synthesis, peptides were purified by reverse-phase HPLC and lyophilized. Homogeneity of synthesized peptides was assesse...

Ngày tải lên: 08/03/2014, 16:20

... Holliday junction binding and processing by the RuvA protein of Mycoplasma pneumoniae Stuart M. Ingleston 1 , Mark J. Dickman 2 , Jane A. Grasby 3 , David P. Hornby 2 , Gary J. Sharples 4 and ... sensitivity to UV light (Fig. 6C), presumably by blocking Holliday junction resolution by RusA [17]. The plasmid encoding MpRuvA also increases sensitivity t o UV, but the effect is considerably le...

Ngày tải lên: 17/03/2014, 17:20

... Denmark; 2 Department of Molecular Biotechnology, Institute of Medical Biology, University of Tromsø, Norway During starvation induced encystment, cells of the myxo- mycete Didymium iridis accumulate a 7.5-kb ... the intron by splicing. They constitute one class out of fewer than 10 classes of naturally occurring ribozymes [1]. Group I introns vary considerably in complexity. Most introns con...

Ngày tải lên: 23/03/2014, 21:20

... H., Ready, M.C., Ready, M.K., Sugi, H. & Amemiya, Y. (1990) X-ray diffraction and electron microscopy from Lethocerus flight muscle partially relaxed by adenylylimidodiphosphate and ethylene glycol. ... during ATP hydrolysis by myosin. The TCSL probe attached to the small SH1–SH2 helix may be a sensitive detector that reports the coupling between the motor and regulatory domains of myosin....

Ngày tải lên: 24/03/2014, 03:21

... rat pituitary. Biochem. Biophys. Res. Commun. 109, 500–506. 43. Tanaka,S.,Yora,T.,Nakayama,K.,Inoue,K.&Kurosumi,K. (1997) Proteolytic processing of pro-opiomelanocortin occurs in acidifying secretory ... vitelline envelope is synthesized by the oocytes [12] while a glyco- protein of fish chorion is produced in the liver and transported to the ovary by blood circulation [13]. Two major gl...

Ngày tải lên: 24/03/2014, 03:21