Báo cáo y học: "eening the human exome: a comparison of whole genome and whole transcriptome sequencing" pot

... directly evaluate the sensitivity and specificity of RNA- Seq in identifying coding variants, and to evaluate how key parameters such as the degree of coverage and the expression levels of genes ... that at only one lane of RNA-Seq data, the specific- ity was 0.5 for SNVs with a read depth of 3, which was far better than the value of 0.28 found when using all ei...

Ngày tải lên: 09/08/2014, 20:22

... leukopenia by 20%, hypother- mia by 14%, and tachypnoea by 9% of physicians. Ability to diagnose sepsis and communicate about sepsis Four in five physicians (911 of 1058) agreed (strongly or somewhat) ... general awareness of the importance and impact of sepsis among the physicians interviewed. A vast majority of physicians consider sepsis a leading cause of mortali...

Ngày tải lên: 12/08/2014, 20:20

... Justin_Gaffney@health.qld.gov.au; Matthew Michael Eastburn - matt.eastburn@uq.edu.au; Joan Faoagali - Joan_Faoagali@health.qld.gov.au; Nancy C Cox - Nancy_Cox@health.qld.gov.au; Ian Brent Masters - Brent_masters@health.qld.gov.au * ... that the description of a cough as wet or dry cough as determined by clinicians and parents has good clinical validity as it has good agreement with,...

Ngày tải lên: 12/08/2014, 18:21

... cells and, alternatively, the capacity of apoptotic cells to induce anergy and a shift to a Th 2 -cell response. Furthermore, apoptosis of gastrointestinal epithelial cells may compromise the integrity ... survival but rather lead to alternative pathways of cell death. Indeed, apoptosis may even be protective, by obviating the potential of injured cells to necrosis and...

Ngày tải lên: 13/08/2014, 18:22

... was possible. The term galvanic labyrinth polarization (GaLa) was originally introduced after the discovery of animal electricity by Galvani [5] and is still employed, despite the fact that the ... administration of sedative ther- apy (see Table 2, demonstrating that sedative therapy was applied to all patients, regardless of whether they showed an OMR). In contrast, muscle re...

Ngày tải lên: 13/08/2014, 20:21

... duplications, the average half-life of a gene copy is of the order of a few million years, with only a small fraction of duplicates surviving beyond a few tens of millions of years (TH and DAL, ... 8:213 Minireview Evaluating dosage compensation as a cause of duplicate gene retention in Paramecium tetraurelia Timothy Hughes*, Diana Ekman † , Himanshu Ardawatia* ‡...

Ngày tải lên: 14/08/2014, 07:21

... pain scale from 0 (no pain) to 10 (unbearable pain) was used for this. Statistical analysis Data was collected using Microsoft Access, and the statis- tical analysis was carried out using STATISTICA ® . ... and 57 (76%) patients after 11-gauge biopsy. The mean persistence of the haematomas in the 8- gauge group was 13 (2–43) days and 10 (2–56 days) in the 11-gauge group. Sca...

Ngày tải lên: 09/08/2014, 07:21

... mirkka.janka@uta.fi; Eeva Moilanen - eeva.moilanen@uta.fi; Hannele Hasala - hannele.hasala@uta.fi; Xianzhi Zhang - Xianzhi.Zhang@uta.fi; Ian Adcock - ian.adcock@imperial.ac.uk; Hannu Kankaanranta* - hannu.kankaanranta@uta.fi * ... data on whether transactivation and/ or transrepression events play a role in the regulation of apoptosis in human eosi- nophils. Based on the hypothesi...

Ngày tải lên: 11/08/2014, 08:21

... muscle layers. The vasa recta, which supply the mucosa and submucosa of the colon, penetrate the circular muscle. The weakness of the vascular portals in the circular muscle possibly causes ... recovery was une- ventful, and the patient was discharged on postoper- ative day 4. Fig.1 Fluid collection and left ovary cyst was noted on computed tomography. The...

Ngày tải lên: 25/10/2012, 10:51

... [7]. Synthetic kaliotoxin (sKTX), P05 and BmTX3 (sBmTX3) were chemically synthesized as previously described [8–10]. IbTX and ChTX were from Bachem Laboratory. Apamin, BSA and a- cyano-4-hydroxycinnamic ... scorpions obtained by manual stimulation was generously provided by the Pasteur Institute at Casablanca, Morocco. Aa1 was obtained from Androctonus australis venom bought from Lat...

Ngày tải lên: 23/03/2014, 21:20